1.Monitoring of oxygen metabolic variables in septic shock patients
Wenxiong LI ; Huide CHEN ; Li WAN
Chinese Journal of General Surgery 1993;0(03):-
0.05). Blood lactate levels in surviving group gradually went down to the normal, while it consistently deteriorated in fatal group.ConclusionsSeptic shock patients had defective oxygen consumption. Patients with higher initial DO 2 had a good outcome. Contineous elevation in blood lactate levels predicts a poor prognosis.
2.Correlation of bone mineral density changes with vertebral deformation and clinical manifestations in patients with cervical spondylotic myelopathy
Jinfa YANG ; Huide CHEN ; Yiwen WU ; Jian TANG
Chinese Journal of Tissue Engineering Research 2010;14(7):1307-1310
OBJECTIVE: To investigate the correlation of bone mineral density changes with vertebral deformation and clinical manifestations in patients with cervical spondylotic myelopathy.METHODS: A total of 42 cervical spondylotic myelopathy patients who received treatment at the Department of Sports Medicine,First Affiliated Hospital of Anhui Medical University from January to June 2009 were selected and randomly divided into the normal (n=20) and lower bone density (n=22) groups. The cervical lateral of the C_(3-8) spinal canal, sagittal diameter of vertebral body ratio, vertebral body deformation index in all cases was measured, and the clinical manifestations between two groups were compared.RESULTS: The cervical (C_3, C_4, C_5, C_6) sagittal diameter of vertebral body ratios of lower bone density group were significantly decreased than those of the normal group (P < 0.05, or P < 0.01), and the cervical (C_3, C_4, C_5, C_6)vertebral body deformation indexes of the two groups showed no significant difference (P > 0.05); While the clinical manifestations (symptoms and physical signs) was significantly greater in the lower bone density group than the normal group (P < 0.05).CONCLUSION: Cervical myelopathy can cause osteoporosis in patients with vertebral bone hyperplasia, spinal stenosis, in particular, the clinical manifestations are more obviously in lower bone density patients.
3.Clinical Characteristics and Diagnostic and Therapeutic Strategies of Severe Cytomegaloviral Pneumonia after Kidney Transplantation
Wenxiong LI ; Huide CHEN ; Xiaowen WANG ; Song ZHAO ; Yue ZHENG
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To summarize the clinical characteristics,diagnositic and therapeutic strategies of severe cytomegaloviral (CMV) pneumonia after kidney transplantation. METHODS To analyze retrospectively pertinent clinical information of 6 cases of severe cytomegaloviral pneumonia after kidney transplantation, including developing process of disease, clinical manifestation of pre-and post-hospitalization ,various assistant examination,therapeutic procedures and prognosis. RESULTS 6 cases had similar characters of episode as follows:CMV pneumonia occurred after 1~3 months after kidney transplantation. Major clinical symptoms included fever, coughing,few sputum without obvious manifestation of breathholding.Peripheral white blood cell was normal or less than normal range, serum CMVpp65 was finally positive during hospital stay. Radiological image of the lung presented inflammatory infiltration and obvious interstitial lesion after 7~10 days of fever, which went worse rapidly. Renal function descended with deterioration of pulmonary infection. All of patients had been treated with multiple antibiotics,glucocorticoid and mechanical ventilation, Etiological diagnosis of the 3th~6th cases were earlier than 1th~2th cases , the 3th~6th cases who finally survived were treated with longer and higher doses of antivirus and glucocorticoid, than 1th~2th cases who died of refractory hypoxemia and acute renal failure during hospital stay. CONCLUSIONS Severe cytomegaloviral pneumonia had similar clinical characteristics of episode. early diagnosis of etiology,continuous application of antivirus and glucocorticoid were crucial for Severe cytomegaloviral pneumonia after kidney transplantation.
4.A study on the relation between hyperglycemia in surgical critical patients and prognosis
Xiaoyan XING ; Huide CHEN ; Xiaowen WANG ; Wenxiong LI ; Son ZHAO
Parenteral & Enteral Nutrition 2004;0(06):-
Objective: To study the relation between hyperglycemia and mechanical ventilatory time, the days in the intensive care unit,infection rate,mortality . Methods: 572 patients' blood glucose levels in the morning were measured,and divided into two groups by the level of 7.78 mmol/L.The mechanical ventilatory time, days in the intensive care unit,infection rate and mortality were compared between two groups. Results: The mechanical time,stay in ICU and infection rate in the group with blood glucose level below 7.78 mmol/L were significantly less than in the group with blood glucose level above 7.78 mmol/L(P
5.The clinical significance of continuous monitoring of monocytes function in septic patients
Wenxiong LI ; Chengqing XIA ; Huide CHEN ; Man QI
Chinese Journal of Emergency Medicine 2006;0(01):-
0.05).Conclusions The patients with sepsis lasting more than 7 days had high mortality (50%). While percentage of CD14 and CD14MFI of peripheral blood are increased,the total scores of SOFA and numbers of MOF are decreased.The improvement of monocytes function indicates good prognosis. The changes of expression of ICAM-1,serum TNF-? and IL-10 can not reflect prognosis in septic patients.
6.The changes and clinical significance of serum TNF?、IL-10 and IL-10/TNF? ratio in septic patients
Wenxiong LI ; Huide CHEN ; Xiaowen WANG ; Xiaoyan XING ; Song ZHAO ; Li WAN ; Baosen PANG
Chinese Journal of General Surgery 1997;0(04):-
0.05). Serum IL-10 and IL-10/TNF? ratio in the dead were significantly higher than that in the survivors( P 0.05). Conclusions The septic patients with high serum IL-10 or IL-10/TNF? ratio fared with poor prognosis.
7.Epidemiological characteristics and related factors of crayfish associated rhabdomyolysis syndrome in Baiyun District, Guangzhou
Hong LIN ; Liangfa CHEN ; Weixuan TAN ; Guihe LUO ; Huide PENG ; Wenting CAO ; Zhuliangzi LU
Journal of Public Health and Preventive Medicine 2021;32(4):71-74
Objective To investigate the clinical and epidemiological characteristics of crayfish associated rhabdomyolysis syndrome in Baiyun District, Guangzhou, and explore the related factors, and to provide evidence for the prevention of crayfish rhabdomyolysis syndrome. Methods The cases of crawfish associated rhabdomyolysis syndrome were found through the foodborne disease surveillance and reporting system, and a field epidemiological investigation was carried out to analyze the clinical and epidemiological characteristics of the cases. Results A total of 25 cases of crayfish associated rhabdomyolysis syndrome occurred in 2020. The intake of crayfish of the cases ranged from 5 to 25, the incubation period was 1 to 9.5h, and the interval from onset to medical treatment was 0.17 to 9h. All the cases had muscle pain, and the content of creatine kinase (CK) in the cases increased to varying degrees (128-17851 U/L). Retrospective cohort analysis of 10 crayfish events found no correlation between the consumption of different parts of crayfish and the incidence of crayfish-related rhabdomyolysis syndrome. Conclusion The incidence of rhabdomyolysis syndrome reported in Baiyun District of Guangzhou is related to the consumption of crayfish, but the pathogenic factors need to be further studied. It is suggested to strengthen the supervision of crayfish breeding, transportation, sales, and processing to ensure the health of consumers.