1.Wang Hui's Smart Experience in Applying Canker-root Wendan Decoction
Journal of Zhejiang Chinese Medical University 2006;0(02):-
Mr. Wang Hui respects but is not stubborn to ancient,paying attention to combination of differentiation of signs and diseases; in smartly applying Canker-root Wendan Decoction,he often adds Chendanxing to reinforce removing heat and sputum,emphasizing that signs of red tongue,yellow and greasy or white moss,bitter mouth,slippery and quick pulse show sputum heat bothering internal,can apply the formula,which embodying the treatment principle of "treat different diseases with same method".
2.Issues related to vascular access in pediatric blood purification
Hui WANG ; Ying SHEN ; Ying LIANG
Chinese Journal of Applied Clinical Pediatrics 2014;29(5):330-332
This article makes a summary on the vascular access issues related to pediatric blood purification and progress,especially in view of the characteristics,principles of selection,maintenance and development direction of various vascular access in application of children patients.
3.DbcAMP inhibitted the proliferation of FTC-133 cell
Yulin WANG ; Hui WANG ; Ying BA
Chongqing Medicine 2015;(24):3325-3327
Objective To study the effect of dualdi butyryl cyclic AMP (dbcAMP)on the proliferation of FTC-133 cell line. Methods FTC-133 cells were normally cultured and divided into control group,dbcAMP treatment group (0.5,1.0,2.0 mmol/L). After FTC-133 cells were treated with dbcAMP (0.5,1.0,2.0 mmol/L)for 24 h or 48 h,the growth activity and growth curve was detected by MTT.Changes of the cell cycle were detected by flow cytometry.The mRNA and protein expression of Raf1 were measured by RT-qPCR and Western blotting.Results Compared with control group,the growth activity of FTC-133 cells was re-duced by different levels of dbcAMP in a dose-time dependence manner.The number of FTC-133 cells was decreased in the S phase and increased in the G2/M phase.The mRNA and protein expression of Raf1 of treatment group were both reduced compared with control group.Conclusion dbcAMP significantly reduced FTC-133 cells proliferation and promoted apoptosis,and which might be involoved by ERK MAPK signalling.
4.Progress of the regulation effect of ginsenosides on HPA axis.
Hui LI ; Shu-Ying LIU ; Bing WANG
Acta Pharmaceutica Sinica 2014;49(5):569-575
Ginseng is a typical adaptogen which has resistance to various stresses. This effect is related to the hypothalamic-pituitary-adrenal (HPA) axis. As the main active ingredients, saponin has the similar structure to steroids. The regulation characteristics of ginseng saponin on the HPA axis are narrated from the aspects of total saponin and saponin monomers in this paper after the introduction of adaptation definition and HPA axis regulation mechanisms. Pharmacological effects of ginseng saponin and the regulation effect of HPA axis are summarized finally.
Adaptation, Physiological
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Adrenocorticotropic Hormone
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secretion
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Animals
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Corticosterone
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secretion
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Ginsenosides
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isolation & purification
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pharmacology
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Humans
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Hypothalamo-Hypophyseal System
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drug effects
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secretion
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Panax
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chemistry
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Pituitary-Adrenal System
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drug effects
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secretion
5.Three-dimensional finite element analysis of stress in the bending root of maxillary first molar
Hui PENG ; Ying ZHANG ; Hongyan WANG
Chinese Journal of Tissue Engineering Research 2013;(33):5949-5956
BACKGROUND:The stress distribution in the periodontal ligament of bending root can provide reference for the size and manner of force in orthodontic treatment. On this account, it can optimize the design of orthodontic force. OBJECTIVE:To analyze the stress distribution of root and periodontal ligament in the bending roots of the
maxil ary first molar under different orthodontic forces.
METHODS:The maxil ary first molars with normal roots and bending roots were selected, and then the finite element models of maxil ary first molars and periodontal ligaments were established through CT scan and
Workbench 11.0 finite element analysis software. The models were loaded with six different methods to analyze the stress distribution.
RESULTS AND CONCLUSION:The stress distribution of bending root was mainly concentrated in the tooth
neck, fol owed by the apex. During the overal tooth movement, the stress was smal est on the root, periodontal ligament and alveolar bone. Correction of bending roots needs more accurate positioning and traction.
6.Poly-peptide immunogenicity of human thyroid-stimulating hormone receptor that may cause Graves' disease
Shuwen QIN ; Ying SHI ; Hui WANG
Basic & Clinical Medicine 2006;0(12):-
DQA1*0501.TSHR peptides of 183~198、195~210、248~263、301~320、343~362 and 357~376 could bind with high affinity to both HLA-DR3 and HLA-DQA1*0501,all of their IC50 values less than(1 ?mol/L),but they could bind to neither HLA-DR7 nor HLA-DQA1*0201 with high affinity.Conclusion Epitopes of TSHR 183~198,195~210,248~263,301~320,343~362 and 357~376 on the TSHR extracellular domain might be the auto-antigens to cause GD.
7.Ultrasonographic Diagnosis of Fetal Craniocerebrum in Second-trimester
Hui LUO ; Ying WU ; Huifang WANG
Journal of Chinese Physician 2001;0(07):-
Objective To explore the ultrasonic imaging features of fetal craniocerebrum, and improve the recognizition on the normal structure and deformity of fetal craniocerebrum. Methods Fetal cranium was measured during 12~40 weeks of gestation, including biaparietal diameter(BPD),lateral ventricular width(LVW),cerebellomedullary cistern(CM), and nuchal translucency(NT) or nuchal fold thickness(NF). Results 18 cases of abnormal craniocerebrum were identified,nine cases of which were accompanied with other abnormalities, and fourteen of which were found during 16~28 weeks of gestation. All cases were proved by subsequent labor or induced labor. Conclusion Second-trimester is the best period of prenatal ultrasound diagnosis of fetal craniocerebrum.
8.Characteristics of research achievement and its transfer strategy in hospital system
Xiaomei NING ; Qing LI ; Ying CUI ; Hui LI ; Ying WANG
Chinese Journal of Medical Science Research Management 2017;30(3):203-205,208
Objective To propose new policies and strategies that will optimize the transformation of medical research achievements at hospital level.Methods In this paper,we systematically analyzed the characteristics and influencing factors of the transformation of medical research achievements based on the status quo in our hospital.Results In our hospital as an example,major problems in the transformation of medical research achievements identified as low investment,low conversion rate,complex procedures,multi-links existed and more multi disciplinary cooperation needed.Conclusions The hospital can take some measurements to optimize the transformation of medical research achievements,such as more stream lined management of scientific research project,establishing and improve the platform for scientific research transfer,increasing the funding,strengthening cooperation among different disciplinaries,building a professional team to promote the transfer and so on.
9.Effects of Tongxinluo capsule on sciatic nerve apoptosis in spontaneous type II diabetic KK/Upj-Ay mice and mechanism research.
Chao WANG ; Hui-xin ZHANG ; Han-ying XING ; Xing WANG
China Journal of Chinese Materia Medica 2015;40(7):1396-1399
To investigate the effects of Tongxinluo capsule on sciatic nerve apoptosis in spontaneous type II diabetic KK/Upj-Ay mice, in order to explore its mechanism for improving diabetic peripheral neuropathy (DPN). KK/Upj-Ay mice were selected as the DPN animal model and randomly divided into the model, Tongxinluo low, middle and high group (1, 2, 4 g x kg(-1)). C57BL/6 mice were selected as the control group. Mice were given intragastrically for 12 weeks. Paw withdrawal latency, motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV) were detected. Apoptotic rate were detected by FCM. Bcl-2, Bax, Caspase-3 mRNA and protein expression in sciatic nerve were examined by Real-time PCR and Western blot. p38MAPK, p-p38MAPK expression were examined by Western blot. In this study,the authors found that Tongxinluo capsule could increase paw withdrawal latency, MNCV and SNCV. Apoptotic rate of sciatic, the expression of Bax and caspase-3 were lower, while Bcl-2 expression was higher in Tongxinluo group than those in model mice. The expression of p-p38MAPK significantly decreased in Tongxinluo group. The results showed that Tongxinluo capsule has protective effects on diabetic peripheral neuropathy of mice via inhibiting cell apoptosis and suppressing the expression of p-p38MAPK.
Animals
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Apoptosis
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drug effects
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Capsules
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administration & dosage
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Diabetic Neuropathies
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drug therapy
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physiopathology
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Disease Models, Animal
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Drugs, Chinese Herbal
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administration & dosage
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Humans
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Male
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Mice
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Mice, Inbred C57BL
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Mice, Transgenic
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Sciatic Nerve
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cytology
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drug effects
10.Evaluation of Antagonism of Penicillium TS67 Against Soy-bean Root Rot Disease and Corn Southern Leaf Blight
Xia WANG ; Su-Ying WANG ; Peng-Hui GAO ;
Microbiology 2008;0(08):-
Through pot experiments, the disease index and control efficiency of TS67 cell, the fermentation liquid of TS67 and the supernatant of TS67 separately act on Fusarium oxysporum and Bipolaris maydis was detected. Experiment results analysis with SPSS statistical analysis software indicated all treatments of TS67 could inhibit both of soybean root rot disease and corn southern leaf blight (P