AlM: To observe the clinical curative effect of calcium dobesilate capsule and yimaikang tablet for treating retinal vein occlusion ( RVO) .METHODS:A total of 120 patients (167 eyes) with RVO were divided into 2 groups at random. The control group of 60 cases ( 82 eyes ) were given calcium dobesilate capsule, and the treatment group of 60 cases ( 85 eyes ) received calcium dobesilate capsule and yimaikang tablet. Changes of visual acuity and clinical effects after 3 courses of treatment were compared and analyzed for all patients.RESULTS: Markedly effective 15 cases ( 23 eyes ) , effective 42 cases (57 eyes) and invalid 3 cases (5 eyes) in the 60 cases (85 eyes) of the treatment group, the total effective rate was 94. 1%. Eighty-two eyes of 60 cases in the control group, markedly effective in 8 cases ( 12 eyes), effective 38 cases (49 eyes), ineffective 14 cases (21 eyes), The total effective rate was 74. 4% in the control group. There were significant differences between the 2 groups of curative effect, and low incidence rate of adverse reaction. CONCLUSlON: Calcium dobesilate capsules and yimaikang tablet is effective and safe in the treatment of RVO.

Side population (SP) cells are highly enriched for stem cell activity and characterized by their ability to efflux the vital dye Hoechst 33342, because they express the ATP binding cassette (ABC)-dependent transporter ABCG2. SP cells can be selected from main population using flow cytometric analysis. Currently SP cells have been isolated from many tissues and organs. SP cells of different origins have some common characteristics. This article introduces the classifications, surface marker, and characteristics of SP cells.

China ; Foundations ; Integrative Medicine ; Natural Science Disciplines

Humans ; Integrative Medicine ; Medicine ; Medicine, Chinese Traditional

Objective To understand change and pathogenesis of microalbuminuria(MAU) in cases of adiposity.Method MAU were measured by immunoturbidmetric methods 300 cases of adiposity and 100 cases of nomal children in morning,meanwhile blood press,blood su-gar,blood fat,blood insulin were measured.Results MAU was higher in cases of middle and severe adiposity than normal controls.The diffe-rence was significant(Pa

Objective To investigate the effects of cobalt chloride(COCl2)induced rat alveolar epithelial cell apoptosis and the significance of related apoptosis protein hypoxia inducible factor-lalpha(HIF-1 a)expression. Methods Alveolar epithelial cells were cultured in vitro and divided into four groups with 6 samples in each.Hypoxia 4 h group:added 500μmol/L COCl2 for 4 hours inducing alveolar epithelial cell hypoxia;hypoxia 24 h group:co-cultured with COCl2 for 24 hours;hypoxia 48 h group:co-cultured with CoCl2 for 48 hours;control group:no CoCl2 added.The apoptosis rates were detected by fluorescent microscope and flow cytometry.The apoptosis morphological changes of the cell were observed by transmission electron microscopy.The protein expression of HIF-la was detected bv Western Blot. Results (1)Fluorescent microscope results showed that apoptosis rate in hypoxia 4 h、24 h、48 h group[(5.83±0.76)%,(15.00±3.28)%and(51.50±3.00)%],were higher than control group[(1.50±0.50)%](P＜0.05).(2)Flow cytometry analysis reached the same results as with fluorescent microscope.(3)Typical morphological changes of apoptosis were observed in hypoxia 24 h group.(4)HIF-1α expression in hypoxia 4 h、24 h and 48 h groups[0.69±0.035,1.02±0.044 and 0.71±0.046],were higher than control group(0.21±0.026)(P＜0.01).(5)Positive correlations were found between relative amount of HIF-1αprotein and apoptosis rate by fluorescent microscope and flow cytometry analysis(r=0.484,P=0.016;r=0.713,P=0.009).Conclusions Hypoxia could induce apoptosis of alveolar epithelial cells,which may participate in the pathogenesis of hypoxia-induced lung injury.

Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases ; diagnosis ; microbiology ; prevention & control ; Mycoses ; diagnosis ; prevention & control

Abscess ; pathology ; Adenoma ; metabolism ; pathology ; Adenoma, Sweat Gland ; metabolism ; pathology ; Biomarkers ; metabolism ; Breast Diseases ; pathology ; Breast Neoplasms ; metabolism ; pathology ; Female ; Fistula ; pathology ; Humans ; Keratin-7 ; metabolism ; Keratins ; metabolism ; Mucin-1 ; metabolism ; Nipples ; pathology ; Paget's Disease, Mammary ; metabolism ; pathology ; Receptor, ErbB-2 ; metabolism ; Sweat Gland Neoplasms ; metabolism ; pathology

Humans ; Noise, Occupational ; Occupational Exposure