AIM: To study mouse's skin ulcer pharmacodynamics of Allantoin Compound Ointment. METHODS: The wounded and scalded skin ulcer models of mice were est ablished. The skin ulcer area of mice was treated with Allantoin Compound Ointme nt and the control group was also ser, and the inflammatory infiltration of the ulcer was observed under the microscope. RESULTS: Compared with the self-control group, the skin ulcer area o f mice treated with Allantoin Compound Ointment reduced obviously (P

Adult ; Anti-Inflammatory Agents ; therapeutic use ; Arthritis, Reactive ; diagnosis ; drug therapy ; etiology ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Male ; Methylprednisolone ; therapeutic use ; Phytotherapy ; Treatment Outcome ; Urethritis ; complications

Child ; Humans ; Inflammation ; Neoplasms, Muscle Tissue ; Ureteral Neoplasms

0.05).No partial side-effect of the medicine were discorvered in the observation process.Conclusion Long-term inspiration of low-dose GCS to treating the babies and infants with asthma has reliable security.

Objective: To explore the ecological adaptability of Angelic sinensis in altitude of 2300-2800 m in Chabu countryside, Min County, Gansu province. Methods: Using the field experiment and correlation analysis, the effect of altitude on the yield formation was explored, and the key factors affecting yield were investgated. Results: The yield of A. sinensis increased with the elevation rising, the yields in the mid-and high-altitudes were higher than that of low-altitude by 30.3% and 22.0%, with significant difference (P < 0.05); The correlation analysis showed that temperature (R2 = -0.7453) and rainfall (R2 = 0.7417) were the key ecological factors, the malonaldehyde (MDA, R2 = -0.9118) and soluble sugar (SS, R2 = -0.8831) were the key physiological and biochemical factors, and the intercellular CO2 (Ci, R2 = -0.7393) and photosynthetic rate (Pn, R2 = -0.7332) were the key photosynthetic characteristic factors influencing the yield of A. sinensis. Conclusion: That is the benefit of the yield formation of A. sinensis by rising altitudes, reducing environmental temperature, increasing rainfall and photosynthetically active radiation, and reducing the contents of MDA, SS, and Ci.

Objective To establish a rat model of pulmonary hypertension induced by left-to-right shunt and explore the influence of high pulmonary blood flow on pulmonary vascular collagen remodeling.Methods Abdominal aorta and inferior vena cava shunting was produced in rats. Pulmonary artery meanpressure (PAMP) of each rat was measured by using a right cardiac catheterization.Pulmonary artery collagen Ⅰ and Ⅲ were detected using immunohistochemisty.Results After 11 weeks of shunting the Qp/Qs was 3.3∶1.0,indicating a large shunt. Pulmonary artery mean pressure was increased as compared with controls[(23.0?0.9) mm Hg vs (15.7? 1.1) mm Hg,P

Child ; Female ; Hemoptysis ; etiology ; Humans ; Lupus Erythematosus, Systemic ; complications ; diagnosis

Animals ; Arthritis ; diagnosis ; pathology ; Arthritis, Rheumatoid ; diagnosis ; pathology ; Humans

OBJECTIVETo observe the efficacy of the treatment of refractory wound by VSD combined with platelet-rich plasma.

METHODSFrom April 2010 to June 2012,15 patients with refractory wound were treated including 11 males and 4 females with an average age of 35.2 years old ranging from 18 to 45 years old. The formation time of wound was from 6 to 24 months, which was unhealed after long-term medication or repeated treatment. The VSD combined with autologous platelet-rich plasma was applied to treat the wound. The wound healing was an indicator and treatment and clinical features were summarized.

RESULTSAll the patients were followed up for 3 to 8 months (means 5 months). The wound of all patients were healed without recurrence.

CONCLUSIONThe curative effect of VSD combined with platelet rich plasma for treatment of refractory wounds is obvious. It could reduce the treatment course and the treatment cost.

Adolescent ; Adult ; Drainage ; methods ; Female ; Humans ; Male ; Middle Aged ; Negative-Pressure Wound Therapy ; methods ; Platelet-Rich Plasma ; metabolism ; Wound Healing ; Wounds and Injuries ; metabolism ; physiopathology ; therapy ; Young Adult

Calcium Pyrophosphate ; metabolism ; Cartilage, Articular ; metabolism ; pathology ; Chondrocalcinosis ; diagnostic imaging ; metabolism ; pathology ; surgery ; Diagnosis, Differential ; Female ; Gout ; pathology ; Humans ; Knee Joint ; diagnostic imaging ; metabolism ; pathology ; Male ; Menisci, Tibial ; metabolism ; pathology ; Middle Aged ; Osteoarthritis ; etiology ; pathology ; Radiography