Objective To understand the status quo of health education requirement of cervical cancer patients undergoing chemotherapy, in order to take individualized health education to improve the quality of life of patients, as well as provide basis for hospitals to conduct targeted health education. Methods 68 cases of cervical cancer patients with chemotherapy were investigated with health education questionnaire. Results Cervical cancer patients with chemotherapy were in general needs of health education, to understand the treatment protocol and effect came to the first place of strong demand. Patients with different times of hospitalization, different age had different emphasis point for health education needs. The most popular education style was oral education. Conclusions Cervical cancer patients with chemotherapy lack knowledge of health education, they hope to obtain health education about examination, treatment and rehabilitation. Nurses should give targeted, planned and individualized health education in order to meet the health needs of patients and improve their quality of life.

OBJECTIVE: To investigate the effect of Compound danshen dripping pills on cytochrome CYP1A2 activity for reference of clinical rational drug use. METHODS: The contents of four major metabolites of Caffeine, i.e. 5-acetylamino-6-formylamino-3-methyluracil(AFMU),1-methylxanthine(1X), 1-methyluric acid(1U) and 1, 7-dimethyluricacid (17U) in the urine before and after oral administration of Compound danshen dripping pills were determined by RP-HPLC. The activity of cytochrome CYP1A2 was derived from the ratio of (AFMU+1X+1U)/17U. RESULTS: The average activity of CYP1A2 was 4.20?1.54 before medication, which stood at 4.26?1.95 at 14 days and 4.35?1.26 at 28 days after medication, up 1.42% and 3.57%, respectively, yet there was no significant difference after medication as compared with before medication. CONCLUSION: No significant difference was noted on CYP1A2 activity after oral medication of Compound danshen dripping pills, nor does it modify the efficacy of the concurrent drugs that metabolized by CYP1A2.

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Panic Disorder ; psychology ; therapy ; Treatment Outcome

ObjectiveThis paper aims to make a research over clinical meaning of VMC with PVB and HRV.Methods22 kids who suffer from VMC with PVB and 28 kids who suffer from HRV and to compare and research their Heart Rate Variability within 24 hours.ResultsThe HRV of the VMC with PVB sufferers had decreased apparently within 24 hours( with discrepancy P ＜0.01 ).ConclusionThere exists apparent DIND in the VMC with PVB sufferers.HRV could be used to check the severness of the disease and prognosis.

Objective:To prepare and characterize chitosan/hyaluronic acid (CS/HA) nanoparticles for miRNA-148b (miR-148b)delivery.Methods:CS/HA/miR-148b nanoparticles were prepared.The particle size,zeta potential,morphology were investigated by nano laser granulometer and TEM respectively.The encapsulation efficiency of CS/HA nanoparticles was evaluated by gel retarding analysis.The cytotoxicity and transfection efficiency of CS/HA/miR-148b nanoparticles on rat bone marrow mesenchymal stem cells (MSCs) were evaluated by CCK-8 assay,transfection assay and FCM respectively.Results:The CS/HA/miR-148b nanoparticles were discrete spherical particles with the diameter of 160 to 370 nm and zeta potential of + 15 to +41 mV.N/P ratio at 20∶1 of the nanoparticles showed the optimum encapsulation efficiency for miR-148b.CS/HA/miR-148b nanoparticles exhibited no cytotoxicity to MSCs and could deliver miR-148b to the MSCs at high transfection efficiency.Conclusion:CS/HA/miR-148b nanoparticles are safe and effective for miR-148b delivery into MSCs.

Objective To compare the effects of hyperbaric oxygenation(HBO) and routine therapy on diabetic foot. Methods Thirty six subjects were randomized to HBO and routine groups. In HBO group,patients stayed in 0.25 MPa HBO chamber for 100 min,wearing masks and inhaling pure oxygen for 60 min,with 10 min interval.This treatment was performed once a day for 10 times as a course,altogether 2 courses for each patient.By means of hemorrheology and electromyograghy (EMG), and the color Doppler ultrasonograghy of lower extremities for detection of the microcirculation states of lower limbs, thirty six patients with diabetic foot were assessed. Results In HBO group all of patients showed that the abnormalities in hemorrheologic, EMG parameters, and the arteria lesions as revealed by Doppler ultrasonograghy were improved more or less compared with before the treatment( P

BACKGROUND:The incidence rate of cervical abnormalities of the patients with skeletal class Ⅱ and normal occlusion has been studied abroad, but the researches on the incidence of cervical abnormalities in different malocclusion patients is rare at home. OBJECTIVE:To observe the imaging of patients with cervical abnormalities and to statistics the incidence of cervical abnormalities in different malocclusion patients through analyzing the lateral cephalogram of different malocclusion patients. METHODS:Skeletal class Ⅱ group was consisted of 93 patients, 41 male (aged 18-40 years) and 52 female (aged 22-35 years), with the A point-nasion-B point angle>5°. Class Ⅰ group was consisted of 45 patients, 31 female (aged 20-36 years) and 14 male (aged 17-38 years), with the 1°

The role of bulletin in subject information service was analyzed, followed by a description of the con-tents, columns, topic selection standards and principles in Bulletin of Global Pharmaceutical Innovation, and a summary of the experiences in subject service through the bulletin.

Objective To study the effect of angelica polysaccharides (APS) on recoverable ability from cryopreservation damage of umbilical cord blood (UCB) hematopoietic cells and APS with hematopoietic growth factors (HGFs) on in vitro expansion of UCB mononuclear cells (MNC) after thawing. Methods Thawed UCB MNC were cultured 24 h or 14 d with various concentration of APS (0,50,100,200,and 400 ?g/mL) or with APS and HGFs. The MNC counting assay,typan blue exclusion assay,colorimetric MTT assay for cell proliferation,CFU-Mix colong-forming assay,and flow cytometry for CD34+ cell rate were detected. Results After adding certain concentration APS in thawed UCB cells,the number of MNC,the rate of trypan blue exclusion,the proliferation of MNC,and the colony production of CFU-Mix were significantly enhanced (P

Objective:To understand the situation of time limitation prescriptions of outpatients in our hospital. Methods:A ret-rospective study was conducted on 1 107 time limitation prescriptions from July 1st to 31th in 2015. Results: There were 1 107 time limitation prescriptions in 16 063 prescriptions (6. 89%), which included 902 patients, and among them, there were more than one time limitation prescription in one day for one patient. As the increase of age, the number of patients with time limitation prescriptions was increased. The number of time limitation prescriptions with the sum between 101 and 200 yuan was the most (34. 51%). The di-agnosis of top 10 of the drugs according to the doctor’ s advice and the actual top ten was substantially consistent, and among them, half were Chinese patent medicines. Conclusion:Time limitation prescriptions are the products of medical insurance policy. The man-agement of time limitation prescriptions can’ t be only defined as the quantity superposition of drugs, and it is necessary to generate in-dividualized strategy according to the properties of diseases, drugs and patients in order to obtain more reasonable management strate-gies, and the ultimate purposes are benefiting patients and obtaining more rational distribution of medical resource.