On the grounds of multicultural coexistence system of Chinese University, this paper propose the basic elements management culture, namely integrity management, innovation management, intelligence management, fine management, system management, which referred to as primitive management culture. This paper also describes the meaning, and explores the function, values and application of primitive management culture. This paper advocates the development of the primitive management culture, and learns primitive management at the same time. We aim to cultivate talent with primitive management cultural qualities, and to achieve the dream of culture encouraged strong school, strong and prosperity nation with the production activities, social and natural science learning and practice.

Objective To analyze the characteristic influence and deviations caused by the face effect to the survey outcomes of the patient perceived value (PPV) of medical treatment.Methods Based on the theoretical research,a PPV test & evaluation plan is designed for two groups of patients.Comparative study of outcomes of the two groups aims at identifying patterns in this regard.Results Findings of the patients evaluation showed that the face effect poses strong interference for the survey outcomes,as it significantly raises the evaluation outcomes.Among the factors causing face effect,characteristics of the investigator in the survey are found to be the most important stimulating,which include the power distance and the strength of relationship between patients and the hospital.Such factor will push higher the subjective PPV of the patient,while the general satisfaction of the medical workers in the survey can be 0.24 higher than that of third-party survey.In addition,friends and patients in the same wards are also an important factor to cause the face effect of the patient,while such factor works at a wide range to push higher both objective and subjective estimation value of the patient.For joint actions of the investigator and the reference group,the general satisfaction between the two-high scenario and the two-low one can be up to 39.43％.Conclusion The PPV surveys should minimize interference of the face effect by means of evaluating environment redesign,avoidance of the friends and relatives,and selection of optimal investigators,for the purpose of eliminating interference of the face effect.

Objective To investigate the effects of meglumine adenosine cyclophosphate administrated before percutaneous coronary intervention (PCI) on curative efficacy, cardiac function and oxidative stress in patients with acute myocardial infarction (AMI).Methods118 patients of AMI meeting the inclusion criteria were selected as research objects.According to therapeutic schemes, those patients were divided into the control group (n=52) and the observation group (n=66).Before PCI, the control group was given conventional treatments.Besides that, the observation group was given meglumine adenosine cyclophosphate.Then, the curative efficacy, indices of cardiac function and oxidative stress were compared.ResultsAfter the treatments, the observation group had higher rates of ST decrease (>50%), thrombolysis in myocardial infarction(TIMI)3 grade (90.9% vs76.9%,84.8% vs 69.2%, P<0.05) and lower peak concentration of creatine kinase isoenzyme(CK-MB), cardiac troponin(cTn)I[(140.6±26.5) U/L比(193.7±30.8) U/L,(1.92±0.24)μg/L 比(2.71±0.32) μg/L,P<0.05].After the treatment, indices of stroke volume (SV), cardiac output (CO) and left ventricular ejection function (LVEF) which reflect cardiac function in the observation group were statistically higher than those in the control group [(57.26±9.37)mL vs.(52.16±9.15)mL,(5.23±1.17) L/min vs(4.49±1.12)L/min,(0.62±0.12) % vs.(0.51±0.15)%,P<0.05].24 hours after PCI, as to oxidative stress, the observation group had a statistically lower level of malondialdehyde(MDA) and higher level of superoxide dismutase[(4.39±0.43)nmol/L vs.(6.45±0.46) nmol/L, [(87.12±10.34)U/mL vs.(68.29±9.48)U/mL), P<0.05].ConclusionMeglumine adenosine cyclophosphate administrated before PCI is effective for patients with AMI.And it can significantly improve cardiac function and alleviate oxidative stress.

Objective To investigate the effect of rosuvastatin on vascular endothelial function and inflammatory factors in patients with acute myocardial infarction ( AMI) after PCI.Methods A total of 217 patients from May 2014 to May 2016 in The Second Hospital of Baoding were randomly divided into the observation group 109 cases and the control group 108 cases.Two groups were treated with conventional basic therapy,and the control group was treated with atorvastatin,while the observation group was treated with rosuvastatin.The clinical efficacy,the levels of FMD and NMD,vascular endothelial function and inflammatory factors were compared between the two groups,and adverse reactions were recorded.Results The effective rate of the observation group was 95.41%,significantly higher than that of 86.11% in the control group (P<0.05);the levels of FMD and NMD in the two groups were significantly higher than before treatment,and the observation group was higher than the control group(P <0.05);the level of ET-1 was significantly decreased,and the levels of NO and NOS were significantly higher in the two groups,and the changes in the observation group were more significant(P<0.05);the levels of hs-CRP,TNF-α,IL-8,IL-6 was significantly decreased,the observation group was significantly lower than the control group( P <0.05 );and no serious adverse reactions were observed.Conclusion Rosuvastatin can improve the vascular endothelial function and inflammatory factor level of AMI patients after PCI,improve the curative effect and improve the quality of life of patients.

0.05);Compared with the control group, the time of first stage(403?135) min and the total time of labor(455?148) min were shorter ( P

Recent research results suggest the existence of cancer stem cell (CSC), a subpopulation of cells with tumorigenic potential that is present in tumor. It has been reported that the occurrence of some tumors is closely related to mesenchymal stem cell as origin of stroma cell. This review discuss the relationship among mesenchymal stem cell, cancer stem cell and cancer.

Objective To investigate the possible association between vascular endothelial growth factor (VEGF), endostatin (ES) and type 2 diabetic nephropathy. Methods The level of serum VEGF and ES were measured by ELISA in eighty type 2 diabetic patients including thirty subjects without diabetic nephropathy , twenty with microalbuminuria and thirty with macroalbuminuria, and the correlation was analyzed. Results The level of serum VEGF and ES in patients with macroalbuminuria were both significantly higher than that of patients with and without microalbuminuria (P < 0.05). The level of serum VEGF and ES in patients with microalbuminuria were significantly higher than that of patients without diabetic nephropathy (P<0.05). Both VEGF and ES level were positively correlated with the level of microalbuminuria (mAlb) (r=0.226, P<0.01; r=0.491, P<0.01), and negatively correlated with the level of estimated glomerular filtration rate (eGFR) (r=-0.237, P<0.05;r=-0.620, P<0.01). There was a significantly positive correlation between VEGF and ES in patients with microalbuminuria and macroalbuminuria (r1=0.633, P1<0.01; r2=0.532, P2<0.05). However, there was no correlation between VEGF and ES in patients without diabetic nephropathy (r3=0.175, P3>0.05). Conclusion The levels of VEGF and ES in type 2 diabetic nephropathy had varying degree of increasing in different diabetic nephropathy stage , and closely related to mAlb and eGFR. Disequilibrium of VEGF and ES may speed up the progression of diabetic nephropathy.

Objective: To investigate the difference in behavioral characteristics among different phenotypes of attention deficit hyperactivity disorder (ADHD) using amplitude of low-frequency fluctuation (ALFF), so as to provide insights into clinical differentiation of behavioral characteristics among different phenotypes of ADHD. Methods: The children with ADHD admitted to The Affiliated Hospital of Hangzhou Normal University were enrolled and classified into the inattentive type (ADHD-I), hyperactive/impulsive type (ADHD-HI) and combined type (ADHD-C). The reaction time (RT) was measured using integrated visual and auditory continuous performance test, and the mean (RT-mean) and standard deviation of RT (RT-SD) were estimated. In addition, the ALFF was calculated at 0.010 to 0.027, 0.027 to 0.073, 0.073 to 0.167 Hz, and the difference of ALFF was compared among children with different types of ADHD. Results: A total of 107 children with ADHD were enrolled, including 95 boys and 12 girls, with a mean age of (8.89±1.93) years. There were 69 children with ADHD-I, 8 children with ADHD-HI and 30 children with ADHD-C. The RT-SD was significantly higher among children with ADHD-C than among children with ADHD-I [(126.003±51.619) ms vs. (97.720±45.302) ms; P=0.007]; however, there was no significant difference in RT-mean among children with various ADHD phenotypes (F=1.386, P=0.255). There was an interaction between frequency and ADHD phenotypes (F=2.754, P=0.032), and the ALFF was significantly higher among children with ADHD-C than among children with ADHD-I at 0.010 to 0.027 [(5 590.567±231.595) ms vs. (4 694.001±154.397) ms; P=0.002] and 0.073 to 0.167 Hz [(4 312.609±174.709) ms vs. (3 690.805±116.473) ms; P=0.005]. Conclusions The ALFF varies in ADHD phenotypes, and there is a frequency-specific difference.