Congenital heart disease and airway anomalies are correlated,and some special cardiovascular anomalies accompanying with airway anomalies like vascular tings,have a high morbidity.Congenital heart disease with airway anomalies is usually ignored in clinic.It should be considered that congenital heart disease with airway anomalies exists in children with the symptoms,such as repeated stridor,respiratory failure,difficult intubation or failure of postoperative ventilator weaning.Multidetector helical CT and bronchoscopy are important for making early diagnosis and guiding management for congenital heart disease with airway anomalies.The choice of therapeutic approaches depends on the type of airway anomalies,location and degree of the lesion.

Acute cerebral infarction needs a fast and effective imaging examination to help determine the diagnosis,analyze the causes,guide the treatment,and determine the prognosis.Multimodal CT examination obtains a wide range of reformation in a single scan,including anatomy,hemodynamics and etiology,and provides objective imaging evidence for comprehensive evaluation and appropriate treatment of cerebral infarction.This article reviews the application of this technology in acute cerebral infarction.

Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Common Cold ; prevention & control ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged

OBJECTIVE: To establish the quality standard of Guanxinjing capsule. METHODS:Ligusticum chuanxiong, Borneolum Syntheticum, Radix Paeoniae Rubra, Panax ginseng and Panax notogiseng were identified qualititively by TLC. The content of Protocatechuic aldehyde in salvia miltiorrhiza was determined by HPLC. RESULTS: The TLC spots were distinct and well-separated. The average recovery of the added sample was 99.91% and RSD was 1.56%. CONCLUSION: The established standard is suitable for the quality control of Guanxinjing capsule.

OBJECTIVE:To optimize the coating technology of modified release film of budesonide colonic localization tablet. METHODS: The effect of the coating parameters such as spray gun position, spraying rate, spraying atomization pressure, intake air temperature and flow, temperature of tablet bed on the microporous semipermeable film and the enteric film of localization tablet were investigated, respectively. RESULTS: The distance between spray gun muzzle and tablet bed was established as 10～20 cm; the spraying rates of the microporous semipermeable film and the enteric film of localization tablet were 3 and 1 mL?min-1, respectively, with their spraying atomization pressure at 2 and 1.5 bar(1 bar=105 Pa), intake air temperature at 50～55 ℃ and 40～45 ℃, temperature of tablet bed at (40?1) ℃ and (30?1) ℃, flow rate of intake air at 5 and 7 m3?min-1 respectively. The weight of the optimized localization tablet after being coated with semipermeable film and enteric film increased by 10% and 5%, respectively. The cumulative drug release within 24 h reached (77.5?8.6)% and the lag time was (6.0?0.5) h. CONCLUSIONS: The optimized coating technology is suitable for the preparation of modified film of budesonide colonic localization tablet.

PBL and CTM integration method is a kind of heuristic education mode of regarding student as the center of education.In order to explore the application result of this teaching method in the curriculum of nursing ethics laws and regulations,we put this mode into practice and regard nursing students as research objects.Questionnaire investigation and paper test are applied to evaluate the teaching effect.The study result shows that PBL and CTM integration method is certainly a well-established method to enhance teaching quality in the curriculum of nursing ethics laws and regulations.

Objective To analyze clinical features of papillary thyroid microcarcinoma(PTMC) and to evaluate the diagnosis and treatment for PTMC.Methods The clinical data of 447 cases of PTMC receiving surgical treatment and confirmed by pathology were reviewed.Color Doppler ultrasonography was used to identify thyroid nodules and cervical lymph nodes,and frozen section was used to confirm the pathological diagnosis during operation.104 cases received unilateral lobectomy,22 cases received unilateral lobectomy plus isthmectomy,321 cases received total thyroidectomy,257 cases underwent central neck dissection,and 54 cases underwent lateral neck dissection(level Ⅵ included).All cases took levothyroxine to maintain low TSH level after operation,and were followed up through telephone or in out-patient clinic.Results Central compartment node metastasis was found in 144 patients,and lateral neck metastasis was found in 41 cN1 cases.The age,extra-capsular invasion and multifocal carcinoma were independent risk factors of PTMC.The number of positive nodes in level Ⅵ was positively correlated with the risk of lateral node metastasis.395 cases were followed-up successfully for 20 to 42 months,with the media follow-up of 32 months.During the follow-up,recurrence or metastasis was found in 15 cases,and no death happened.Conclusions PTMC has no specific symptoms,and was difficult to be diagnosed before operation.Physical examination and color Doppler ultrasonography should be used as routine examination.Thyroid lobectomy and total thyroidectomy plus central node dissection should be major surgical treatment for PTMC patients.Lateral neck dissection should be considered in all cN1 patients.

Objective To estimate the clinical effect of cutting titanium inlay crown in the restoration of short cracked molar. Methods Sixty-four short coronal cracked teeth were randomly divided into group A and group B. Group A were treated by crown. Group B were treated by titanium inlay crown. The curative effect was evaluated every year and lasted 2 years. Results One year after the repair, there was no significant difference in the achievement ratio between two groups (93.8%vs 100%,χ2=2.064, P>0.05). Two years after the repair, the success rate was significantly higher in group B (96.9%) than that of group A (68.8%,χ2=8.892, P<0.01). The failed cases of group A were treated by cutting titanium inlay crown, showing good retention. Conclusion The retention of a short cracked molar can be improved by means of cutting titanium inlay crowns.

Positron emission tomography-computed tomography (PET-CT) is widely used in the diagnosis and grading of FDG-uptake lymphoma,particularly in the extranodal lesions.Baseline PET-CT improves the accuracy of subsequent response assessment.Focal FDG uptake within the bone or bone marrow is highly sensitive for involvement in Hodgkin' s lymphoma (HL) and diffuse large B-cell lymphoma (DLBCL) and is better than bone marrow biopsy.Many international trials suggest that interim scan is prognostic,but not proven as a method to guide therapy.A negative PET-CT scan at the end of therapy is the best predictor of a good outcome.However,surveillance PET-CT scan should not be done routinely.

Objective To evaluate the application value of serum endotoxin combined with integrated model for end-stage liver disease (iMELD) in evaluating the short and medium term prognosis of patients with decompensated liver cirrhosis.Methods The clinical data of 68 patients with decompensated liver cirrhosis were retrospectively analyzed.The patients were divided into survival group and death group according to the result of follow-up at the 3,6 and 12 months.The iMELD score and Child-Turcotte-Pugh (CTP) score were calculated according to relevant indicators,and the serum endotoxin level was detected.The correlation between serum endotoxin and iMELD score was analyzed in the short and medium term prognosis in patients with decompensated liver cirrhosis.Results After 3 months' follow-up,5 patients died.The iMELD scores in survival group and death group were (39.26 ± 7.29) and (49.29 ± 8.63) scores,CTP scores were (9.32 ± 2.12) and (12.03 ± 2.75) scores,serum endotoxin levels were (9.21 ± 2.24) and (15.39 ± 5.12) ng/L,and there were statistical differences (P ＜ 0.05).After 6 months'follow-up,12 patients died.The iMELD scores in survival group and death group were (41.35 ± 8.03) and (52.18 ± 10.37) scores,CTP scores were (9.78 ± 2.05) and (12.93 ± 1.99) scores,serum endotoxin levels were (8.96 ± 2.41) and (16.43 ±6.03) ng/L,and there were statistical differences (P ＜0.05).After 12 months' follow-up,19 patients died.The iMELD scores in survival group and death group were (40.74 ± 6.38) and (52.29 ± 8.53) scores,CTP scores were (10.01 ± 2.23) and (13.27 ± 1.69) scores,serum endotoxin levels were (8.53 ± 2.34) and (16.52 ± 6.08) ng/L,and there were statistical differences (P ＜ 0.05).The area under curve of receiver operating characteristic (ROC) was 0.952,standard error was 0.048,and 95％ confidence interval was 0.790-1.022.The best critical value of iMELD score to predict death was ≥48.00 scores,and the risk of death would rise if iMELD score was increased.The best critical value of serum endotoxin to predict death was ≥ 11.00 ng/L.Conclusion iMELD score and serum endotoxin have important value in predicting prognosis in patients with decompensated liver cirrhosis.