Penis is one of the most important components of male external genitalia.Congenital abnormalities and trauma may lead to genitourinary organ damage or default,which require reconstruction.With the development of tissue engineering(TE),penile corpora cavernosa tissue engineening has becoming the core of the penis reconstruction.Recent researches mainly focus on forming scaffolds and transplanting cells(including of endothelial cells and caveruosal smooth muscle cells). Recently, stem cell technology, gene therapy and nervous reconstructive techniques have been combined to promote the development of tissue engineering.Tissue engineering has been thought to be able to make possible the restoring and constructing of the structure and normal funetion of penile corpora cavernosa.This paper gives a review of the recent progress in associated researches on tissue engineering of the penile corpora cavernosa.

Objectives To investigate the specific site for measuring inferior alveolar nerve canal (IANC) by cone beam computed tomography (CBCT),and to provide reference data of the course of the IANC of the crowd.Methods This study was a retrospective data analysis.One hundred and thirty CBCT cases were measured and compared after classification by gender and age (65 men and 65 women,65 middle age and 65 youth).Since the proximal center of the mental foramen area,the cross-section at which the mental hole just completely breaks the buccal cortical bone was defined as S1,and S2,S3,S4 were defined as cross-sections with 1-cm apart from each other since S1.L1,L2,L3,and L4 were measured as the distance from specific sites on the outer wall of the IANC to the alveolar crest,the outer wall of lingual lateral cortical bone,the mandibular minimum margin,and the outer wall of buccal cortical bone.The results were analyzed using independent samples t test,with P＜0.05 being considered statistically significant.Results On the right IANC S2L1,S3L1,S4L1,S2L2,S3L2,S4L2,S1L3,S3L4,the 8 groups of L values measured on these 8 sites,all showed differences between genders (P＜0.05).So did the 10 groups of L values measured on the left IANC S1L1,S2L1,S3L1,S4L1,S1L2,S3L2,S4L2,S2L3,S3L3,S4L4 (P＜0.05).The middle age group and the youth group were statistically different for the data measured on the right IANC S2L4 (P＜0.05).This was the same case for the data measured on the left IANC S1L3.When classified according to gender,L1 in the S1 to S4 sections firstly increased and then decreased,and eventually decreased.The change pattern of L3 was opposite to that of L1.L2 in the S1 to S4 sections firstly decreased and then decreased,and eventually increased.The change pattern of L4 was opposite to that of L2.When the samples were classified according to age,the change pattern L value in the S1 to S4 sections was the same as that under gender classification.Conclusions The effect of gender on the L value of individuals is relatively great,while the effect of age on the L value of individuals value is very small.Setting the corresponding long axis of mandible as a reference,the change pattern of IANC in the mandible can be deduced based on the change of L value from S 1 to S4:from S1 to S4,the course of IANC on the vertical direction is firstly downward,tben turns to upward and goes upward;from S1 to S4,the trend of IANC on the horizontal direction is firstly toward the side of tongue,and eventually turns towards the buccal side.The current study provides reference data for IANC-related anatomy from the mandibular foramen to the mandibular second molars.

Objective To investigate the clinical efficacy of autologous cultured pure melanocytes for treatment of patients with acral vitiligo.Methods Sixty-two (including 96 skin lesions) patients with acral vitiligo were divided into two groups by treatment methods:narrow-spectrum midwave ultraviolet ray treatment group (group A) 50 skin lesions and autologous cultured pure melanocytes group (group B) 46skin lesions.The clinical efficacy between the two groups was compared.The melanocyte division time (MDT) was calculated.Results The effective rate in group B was significantly higher than that in group A [71.7％(33/46) vs.36.0％(18/50),P＜ 0.05].No significant relationship was found between clinical efficacy with age,position of skin lesions and course of disease in group B (P ＞0.05),however,the clinical efficacy was significantly related with MDT in group B (P＜ 0.05).Conclusion Autologous cultured pure melanocytes is an effective method for the treatment of acral vitiligo,and the MDT plays a major role in affecting its clinical efficacy.

Objective To investigate the application value of the plasma homocysteine (Hcy) ,folic acid (FA) and vitamin B12 (VB12 ) levels in the patients with coronary heart disease (CHD) and CHD complicating impaired glucose tolerance (IGT) .Methods 80 triers screened by the inclusion criteria were divided into the simple CHD group (36 cases) and the CHD complicating IGT group(44 cases);70 healthy cases were taken as the controls .Hcy ,FA and VB12 levels were measured and the detection results were performed the statistical analysis .Results The Hcy level in both experimental groups were higher than that in the control group , the difference was statistically significant (P<0 .05) ,the positive rates were 94 .4% in the simple CHD group and 88 .6% in the CHD complicating IGT group respectively ;The plasma FA level in both experimental groups were lower than that in the control group ,meanwhile ,plasma Hcy level and FA level showed a negative correlation (P<0 .05);The VB12 level had no statistical differ-ence among 3 groups (P>0 .05) ,and the correlation analysis between the Hcy level in the two experimental groups with VB 12 had no statistical significance (P>0 .05) .Conclusion Plasma Hcy level in CHD and CHD complicating IGT is very high and negatively correlated with the FA level ,dynamically detecting the Hcy level has an important significance for early warning and treatment of CHD and CHD complicating IGT .

Plastic bronchitis is a “multiple-system” involved syndrome that is characterized by the formarion of thick,arborizing mucofibrinous tracheobronchial casts,which can result in hard breathing or pulmonary failure.Plastic bronchitis in children occurs following correction of complex cardiac defects,or in children with inflammatory pulmonary conditions.It is a condition of unknown causes and has different clinical manifestations.Early diagnosis is very important and so far endoscopic removal of the casts is the most effective measure.

A scientific and rational questionnaire for emotional work was designed according to the 5 factors and 30 items screened by item analysis, confidence analysis and efficiency test based on the references and twice questionnaire investigations, in order to provide reference for the emotional work management in academic libraries.

Therapy methods of esophageal carcinoma have gradually becomecomprehensive treatment according to precise preoperative staging,Traditional preoperative examinations are difficult to meet the requirements of preoperative staging.The level of preoperative staging in esophageal carcinoma is improved by the progress of endoscopic esophageal ultrasound(EUS),EUS-FNA,three-dimensional re-construction,integrated PET-CT,endoscopic techniques and so on.

ObjectiveTo find the death predictors of acute Stanford type B aortic dissection patients by studying relationships between complications and prognosis. MethodsEighty-four patients with acute Stanford type B aortic dissection were included, the complications of pericardial fluid, pleural effussion,conscious disturbance ,oliguria, gastrointestinal tract bleeding and the level of creatine kinase were analyzed.There were 73 men and 11 women with age 30 - 81 (52.0±12.7) years old. ResultsThe overall mortality was 9.5％(8/84). There were 33.3％ (1/3) died with pericardial fluid, 35.7％ (5/14) died with pleural effussion, 50.0％ (2/4) died with gastrointestinal tract bleeding, all patients died with oliguria and conscious disturbance, 36.4％(4/11 ) patients died with elevated creatine kinase. The patients suffered from any of the complications had higher mortality than those free from complications. There was significant difference between patients suffering from pleural effussion, gastrointestinal tract bleeding,oliguria,conscious disturbance and high level of creatine kinase and who not suffering from the complications respectively in statistically (P ＜ 0.05 ). Logistic regression showed that pleural effussion was independent death predictor.ConclusionsThe mortality increases when acute Stanford type B aortic dissection patients combined with pleural effussion, gastrointestinal tract bleeding,oliguria, cons cious disturbance or high level of creatine kinase. Pleural effussion is independent death predictor.

Objective To understand the status quo of health education requirement of cervical cancer patients undergoing chemotherapy, in order to take individualized health education to improve the quality of life of patients, as well as provide basis for hospitals to conduct targeted health education. Methods 68 cases of cervical cancer patients with chemotherapy were investigated with health education questionnaire. Results Cervical cancer patients with chemotherapy were in general needs of health education, to understand the treatment protocol and effect came to the first place of strong demand. Patients with different times of hospitalization, different age had different emphasis point for health education needs. The most popular education style was oral education. Conclusions Cervical cancer patients with chemotherapy lack knowledge of health education, they hope to obtain health education about examination, treatment and rehabilitation. Nurses should give targeted, planned and individualized health education in order to meet the health needs of patients and improve their quality of life.