1.Percutaneous radiofrequency ablation for treatment of liver tumor
Hongmei WANG ; Yide HU ; Guoqing LIAO ; Huchen LI
Journal of Third Military Medical University 1984;0(01):-
Objective To study the curative effect of percutaneous radiofrequency ablation (PRFA) on liver tumors. Methods A total of 66 patients underwent PRFA under ultrasound guidance for the total frequencies of 146. AFP, B-US, and CT examinations were conducted before and after the operation. A follow-up for 6 months was carried out. Results PRFA was successfully performed on all patients. Serious complications and death were found in 2 cases. The follow-up revealed complete disappearance of tumor masses in 6 cases. The diameter of tumor reduced by 1/2 were found in 24 cases, and
2.Predictors of local recurrence and survival in primary retroperitoneal leiomyosarcoma.
Guibing CHEN ; Yang YAN ; Chunhong XIAO ; Peiming SUN ; Huchen XUE ; Rong LI
Chinese Journal of Surgery 2014;52(2):105-108
OBJECTIVETo investigate the predictors of local recurrence and survival in primary retroperitoneal leiomyosarcoma (PRLS).
METHODSA retrospective analysis was conducted on 46 cases of PRLS between August 2006 and April 2012. There were 9 male and 37 female patients, and they were 30-79 year old (median 49 year old). Kaplan-Meier estimations and Cox regression analyses were performed.
RESULTSThe tumor size were 5-36 cm, and 29 cases (63.1%) of this group was more than 10 cm. Local 3- and 5-year control rates after complete resection were 47% and 30%. FNCLCC (Fédération Nationale des Centres de Lutte Contre le Cancer) grading (RR = 3.10, 95%CI: 1.59-6.04), gender (RR = 5.30, 95%CI: 1.64-17.13) and blood loss (RR = 3.12, 95%CI: 1.28-7.60) were independent prognostic factor of local recurrence in multivariable analysis (P < 0.05). The 5-year disease-free survival rates after complete resection of PRLS was 26%; and the 5-year disease-specific survival (DSS) rates after complete resection was 48%. The median DSS was 60 months in negative margin of resection and 50 months in positive margin. However, by multivariate analysis, only FNCLCC grading was significant independent predictors of DSS (RR = 2.01, 95%CI: 1.16-3.49, P = 0.013).
CONCLUSIONSGender, FNCLCC grading and blood loss were independent prognostic factor of local recurrence. The disease-specific survival in PRLS varied significantly according to FNCLCC grading.
Adult ; Aged ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Leiomyosarcoma ; pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; pathology ; Prognosis ; Retroperitoneal Neoplasms ; pathology ; Retrospective Studies ; Survival Rate
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