1.Changes of Serum Thyroid Hormone and Lp(a) in Elder Patients With Congestive Heart Failure
Huazhu LI ; Xianghua LIU ; Boxi ZHOU
Journal of Chinese Physician 2000;0(12):-
Objective To investigate the relationship between thyroid hormones and Lp(a) the pituitary-thyroid axis in elder patients with congestive heart failure(CHF). Methods 50 normal controls and 158 elder patients with CHF who had not thyroid gland illness were involved in this study. Levels of FT 3, FT 4, TSH and Lp(a) in serum were measured. Patients were divided into two groups according to the course of chronic heart failure: patients with the course of CHF
2.The experimental research of R-Salbutamol on inhibiting the contraction of isolated tracheal smooth muscle in guinea-pig
Yun SUN ; Wen TAN ; Huazhu ZHOU ; Qing LIU
Chinese Pharmacological Bulletin 1987;0(02):-
Aim To evaluate the effects of R-Salbutamol(R-Sal)on the contraction of isolated tracheal strips and lung parenchyma strips in guinea-pig,induced by Histamine(His).Methods Tracheal strips and lung parenchyma strips of guinea-pig in vitro were prepared,and the dilatory effect on shrinkage reaction of isolating specimens induced by His were measured before or after the administration of R-Sal in doses of 10-8,10-7,10-6 mol?L-1,with fix-doses pharmacology methods.The inhibitory effect was compared with that of Sal(10-6 mol?L-1).Results His could induce the contraction of isolated strips in guinea-pig in a dose-dependent manner,and R-Sal could significantly inhibit this shrinkage of lung parenchyma induced by His.in a dose-dependent manner.R-Sal was much more efficient than Sal(P
3.EFFECTS OF ANISODAMINE ON HEMOD-YNAMICS & CARDIAC PUMP FUNCTION IN ANESTHETIZED DOGS
Zuoping REN ; Minghua LIANG ; Huazhu ZHOU ; Al ET ;
Chinese Pharmacological Bulletin 1987;0(01):-
Experiments were carried out in 14 closed-chest dogs anesthetized with urethane and chloralose. The tracings of FAP, the 1 st derivatives of cardiac impedance variations ( dZ/dt) , PCG and ECG were recorded synchronously on a SJ-42 Polygraph. CO and STI were determined according to Kubicek and Weissler, respectively.5-10 min after injection of 5 mg/kg wt of anisodamine intravenously, MAP and TPR reduced drastically, accompanied by a slight slowing in HR and a moderate decrease in CO; increased PEP/LVET associated with lengthening of Q-Z interval and reduction of Heather's index. There were significant differences (P