1.Design and Realization of Decompression Escape Timer Control Program
Kan LIU ; Xi DENG ; Huasheng DING
Chinese Medical Equipment Journal 1993;0(06):-
Objective To develop a control program running on the magnetic induction escape decompression control timer. Methods The software was developed by VHDL in a modular style under the environment of Quartus II. Results The control software stores decompression profile and accurately controls the commitment of the decompression process. Conclusion The program can work accurately according to the profile selected and meet our needs perfectly.
2.Correlation of serum total bile acid levels with liver tissue inflammation grade in chronic liver diseases
Xianjun DING ; Shibo LI ; Yuncheng LI ; Zhejuan YANG ; Shaozuo LI ; Huasheng LIU ; Zhiyi LIN ; Jianrong HUANG
Chinese Journal of Clinical Infectious Diseases 2011;04(6):352-354
Objective To investigate the correlation of serum total bile acid (TBA) levels with the inflammation grades of liver tissue in chronic liver diseases.Methods Cyclophorase assay was used to detect the serum TBA levels in 172 patients with various chronic liver diseases,and the inflammation grades of liver tissue were determined by liver biopsy.The correlation between serum TBA levels and the inflammation grades of liver tissue was evaluated using SPSS 12.0 software.Results Serum TBA level was positively correlated with the inflammation grade of liver tissue ( r =0.275,P < 0.01 ).The inflammation grade reached G2 when serum TBA was 20 μmol/L.Conclusion Serum TBA level may be useful for evaluating the inflammation grade of liver tissue in chronic liver diseases.
3.Effect of paeonol on expression of HMGB1,IL-1βand apoptosis of cardiomyocytes in rats after myocardial I/R injury
Chinese Journal of Geriatric Heart Brain and Vessel Diseases 2019;21(5):522-524
Objective To study the effect of paeonol onexpression of HMGB1and IL-1βand apoptosis of cardiomyocytes in rats after myocardial I/R injury.Methods Fifty-two adult SPF male SD rats were randomly divided into sham operation group,low-dose paeonol group,high dose paeonol group,and I/R injury group(13in each group).The rats in low-dose paeonol group and high dose paeonol group received intraperitoneal paeonol injection before operation(15.30mg/kg,once a day).Serum samples were taken at 2hafter reperfusion.Serum IL-1βlevel was measured by ELISA,myocardial infarction size was measured with TTC staining,expressions of HMGB1,Bcl-2and Bax proteins in myocardial tissue were detected with immunohistochemical staining.Results The myocardial infarction size was significantly smaller in low-dose paeonol group and high dose paeonol group than in I/R injury group(31.04%±2.93%,27.97%±2.84 vs37.23%±3.62%,P<0.01).The expression levels of IL-1βand HMGB1were significantly higher in I/R injury group,low-dose paeonol group and high-dose paeonol group than in sham operation group and were significantly lower in low-dose paeonol group and high-dose paeonol group than in I/R injury group(P<0.01).The expression level of IL-1βwas significantly higher while that of Bax protein was significantly lower in low-dose paeonol group and high-dose paeonol group than in in I/R injury group(P<0.05).Conclusion Paeonol preconditioning can reduce apoptosis of cardiomyocytes,and can thus prevent myocardial I/R injury.