1.Validity evaluation of dipstick dye immuno-assay(DDIA)for screening in low endemic areas of schistosomiasis
Shiwei ZHANG ; Bin CHENG ; Hongjie QU ; Zhongmin CHEN ; Qin ZOU ; Liping CHU ; Lin ZHANG ; Huanran HE ; Shenghua TANG ; Xiaoping HUANG ; Hengmei YANG
Chinese Journal of Schistosomiasis Control 2010;22(2):171-173
Objective To explore the application value of dipstick dye immuno-assay (DDIA) for screening the schistosomiasis chemotherapy targets in the low endemic areas of Xiaogan City.Methods The residents aged 6-65 years in a village in the low endemic areas of schistosomiasis of Xiaogan City were selected and tested by the methods of fecal examination,DDIA,indirect hemagghitination (IHA),enzyme linked immunosorbent assay (ELISA) and inquiry,and the results of fecal examination were determined as the gold standard.Results The Youden' s indices of IHA,DDIA,ELISA and inquiry were 0.74,0.72,0.62 and 0.30,respectively,and the consistency rates of them were 93.38%,91.99%,81.53% and 70.03%,respectively.It took 16.70,4.95,4.12,5.63 and 2.44 Yuan screening one patient with the fecal examination,IHA,DDIA,ELISA and inquiry,respectively.Conclusion The validity of DDIA with simple operation and low cost for screening the schistosomiasis chemotherapy targets is satisfying,and the method is suitable for large scale screening in low endemic areas.
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