Objective To explore the difference of the results between pup smear and liquid-based cytology (TCT) in cervical lesions.MethodsA total of 150 patients undergoing routine cytology were enrolled in the department of obstetrics and gynecology in Hangzhou Wuyunshan sanatorium from May 2015 to December 2016.The patients were treated with liquid-based cytology (TCT) and Papanicolaou Smear examination;and liquid-based cytology method as the study group, and Pap smear the control group.The difference of the diagnostic results between the two groups were compared.ResultsThe positive rate of ASCUS detection, LSIL detection rate and HSIL detection rate were significantly higher in the study group than those in the control group (P<0.05).The difference between the two groups was statistically significant (P<0.05).Compared with the results of colposcopic biopsy, the diagnosis of LSIL coincidence rate in the study group was significantly higher than that in the control group, the difference between the groups was statistically significant (P<0.05).ConclusionCompared with pap smear examination, liquid-based cytology has a more obvious advantage in cervical lesions, which can significantly improve the positive rate of cervical lesions, reduce the false negative results, with a higher diagnostic compliance rate, and therefore worthy of clinical application.

Objective To study and observe the changes of pancreatic blood flow and blood miR indexes of patients with pancreatic cancer.Methods 70 patients with pancreatic cancer were selected as the observation group,70 health persons of the same age at the same period were selected as the control group, then the blood flow indexes and blood miR of observation group’s lesion and tumor adjacent tissue and control group’s healthy pancreas were detected,and the detection results of control group and observation group were compared,then the above indexes of observation group with different Hemrick stages were compared.Results The lesion blood flow indexes of observation group were all obviously worse than those of control group(P<0.05),blood miR indexes were all higher than those of control group(P <0.05),the lesion and tumor adjacent tissue blood flow indexes all had obvious differences(P<0.05),and the above indexes of observation group with different Hemrick stages all had significant differences(P<0.05).Conclusion The pancreatic blood flow and blood miR of patients with pancreatic cancer all show obvious abnormal state,and the differences of indexes of patients with different Hemrick stages are all prominent, so the pancreatic blood flow and blood miR indexes all have higher value for the patients with pancreatic cancer.

Epistaxis ; diagnosis ; etiology ; Hemophilia B ; complications ; diagnosis ; Humans ; Male ; Young Adult

ObjectiveTo investigate the mentation of the female in mammography examination. Methods292 female patients (over 35 years old) from the out-patient department accepted the psychological questionnaire survey.ResultsMost female patients showed some mental problems, include angst, discomposure, tension or funk for examination. They worried about examination result and the damage being exposed to the X-ray irradiation.ConclusionTechnicians should pay attention to the mentation of the female in mammography examination to win their trust and cooperation.

Drugs, Chinese Herbal ; therapeutic use ; Humans ; Renal Insufficiency, Chronic ; drug therapy

The examinations of blood and bone marrow in 125 patients with visceral leishmaniasis revealed that seven routine parameters of the blood samples were below the lower limit of normal in most cases and 64.8% of the cases showed complications with iron deficiency anemia(IDA) and cell maturation disorders.Therefore, iron deficiency anemia and significant reduction of blood components can be used as indicators on the severity of Leishmania infection.

Objective To compare the clinical efficacy of moxibustion Zhiyin with knee chest decubitus,ear acupoint magnetic bead press combined with knee chest decubitus and knee chest decubitus in correction of breech position,thus to provide more safe and effective correction method for the clinical treatment.Methods 150 pregnant women with breech were selected.They were randomly divided into observation group Ⅰ,observation group Ⅱ and control group according to the digital table,50 cases in each group.The control group was treated with knee chest decubitus to correct breech position,the observation group Ⅰ was given moxibustion Zhiyin combined with knee chest position,the observation group Ⅱ was given ear acupoint magnetic bead press combined with knee chest decubitus.Results The effective rates of the observation group Ⅰ and observation group Ⅱ were 96％,92％,respectively,which were higher than 76％ of the control group,the difference were statistically significant (χ2=5.09,4.18,all P＜0.05).The effective rate between the observation group Ⅰ and observation group Ⅱ showed no significant difference (P＞0.05).Conclusion Moxibustion Zhiyin combined with knee chest decubitus and ear acupoint magnetic bead press combined with knee chest decubitus in the correction of breech position have short course of treatment,high success rate,and are more economical and convenient,with high safety and good curative effect,which are worthy of promotion.

AIM:To investigate the effect of tanshinone IIA on the apoptosis of human umbilical vein endothe -lial cells (HUVECs) after high glucose treatment.METHODS:The cell viability was determined by MTT assay.The cell apoptotic rate was examined by flow cytometry with Annexin V-FITC/PI double staining .The expression of Bcl-2 and Bax, and the release of mitochondrial cytochrome C ( Cyt C) were analyzed by Western blotting .RESULTS: Tanshinone IIA significantly inhibited high glucose-induced decrease in cell viability and increased the cell apoptosis .Additionally, after tanshinone IIA treatment , Bax expression and the release of mitochondrial Cyt C were significantly inhibited , while Bcl-2 expression was increased .CONCLUSION: Tanshinone IIA prevents high glucose-induced endothelial cell apoptosis via mitochondria-dependent pathway .

Antitussive Agents ; poisoning ; Child, Preschool ; Dextromethorphan ; poisoning ; Humans ; Male

Objective To evaluate the clinical effects of autologous bone marrow transplantation(ABMT) in the treatment of patients with acute leukemia.Methods A retrospective study was accomplished on the ABMT in the treatment of 35 patients with acute leukemia from Oct 1999 to Oct 2004.The median age of the patients was 32.5(9～55) years.Of the 35 patients,26 cases were acute non-lymphocytic leukemia(ANLL) and 9 cases were acute lymphoblastic leukemia(ALL).The patients were pretreated with melphalan(140～180mg/m~2),cyclophosphamide(120mg/kg) and arabinosylcytosin(3g/m~2).Results All patients engrafted successfully.The median follow-up duration was 756(186～1950) days.The 3-year probabilities of disease-free-survival(DFS) for ANLL and ALL were(65.4%?8.9)% and(33.3?13.6)% respectively,and the probabilities of relapse were(30.6?9.2)% and(60.7?25.5)%,respectively.Conclusion To decrease relapse and increase DFS,patients with acute leukemia who have no chance for allogene haemopoietic stem cell transplantation are recommended for ABMT.