This paper Summarized Wu Jutong's academic thought and diagnosis and treatment characteristics. The contribution of Wu Jutong to the traditional Chinese medicine was his legislation and theory of innovation, especially for the treatment of febrile diseases. Many prescriptions and theories that he left has been further improved TCM in exogenous diseases and febrile diseases treatment. Besides he also made great achievements on the diagnosis and treatment of arthralgia syndrome and diarrhea diseases. The academic thought and clinical characteristics of Wu Jutong had important practical significance to the prevention and control of emerging infectious diseases and infectious diseases.

Objective To investigate the influence of Tanyu-Tongzhi (TYTZ)recipe on Rho/Rho kinase signal transduction pathway of myocardial ischemia-reperfusion injury in high fat-fed rats.Methods 60 SD rats were divided into 5 groups randomly,a sham-operated group,a model group,a western medicine control group,a high-dose group and a low-dose group of TYTZ recipe.The model of ischemia reperfusion of the myocardium was reproduced by ligation of left descending artery for 30 min followed by releasing the ligation for 2 hours in rats.The downstream substrates of ROCK myosin light chain (MLC) phosphorylation expression of myocardial tissues in rats were detected by Western blotting method.The levels of RhoA,ROCK Ⅱ mRNA were determined with RT-PCR.Results Compared with the model group,the expression of p-MLC and RhoA,ROCK Ⅱ mRNA were lower in low-dose group of TYTZ,there were significant differences between the two groups(P=0.004、0.003、0.018、0.004,P＜0.01).Conclusion The TYTZ Recipe can protect myocardium from MI/RI.The mechanism of action was related to its inhibiting the protein expression of RhoA,ROCK Ⅱ and p-MLC,restraining the activation of Rho/Rho kinase signal transduction pathway.

Objective To discusse the research status ofyanjing medical school experience method, and provide a reference for relative researchers.Methods Articles in TCM Database System, SinoMed and CNKI were retrieved refined and analyzed t from the year, author, journal, organization and so on after duplicate removing.Results There were 389 related articles published in journals from 1956 to 2012. With 41.90% articles published in 10 core journals, written by 14 main authors. There were 3 hot research areas including experience of famous doctor,syndrome differentiation and treatment and medical record.Conclusion There was lacking of combing on Yanjing medical school and inheritance system. The inheritance of Yanjing medical school was done far from good, and the study on how to inherit Yanjing medical school need strengthening.

In order to scientifically classify ancient TCM literature and promote the development and use of the literature, this paper combs the classification methods used in the bibliography literature, the modern databases and the libraries of TCM, analyzes the features of the classification methods, summarizes the existing problems in the classify of ancient TCM literature, and proposes the solutions.

With medical literature in local chronicles before 1949 as the research object,this paper introduces the existing research results and existing problems from two aspects of books and papers.Then it summarizes the compiling standard of all kinds of medical literature in local chronicles,and points out that the literature can be arranged by bibliography collection,database construction,information analysis,so as to support and complement the content of existing TCM classics,and provide new clues and basis for scientific research of traditional Chinese medicine.

It is urgent to establish a standard for the classification and management of ancient books for Traditional Chinese Medicine (TCM) industry. This paper formulated the compiling principles on classification of TCM ancient books through the investigation and research. The categories were set and adjusted by comparing with the classification of Zhongguo Zhongyi Guji Zongmu and Zhonghua Guji Zongmu. Based on the comparason, the standard on classification of TCM ancient books was established. According to the classification standard, 8 663 kinds of TCM ancient books were reclassified. This standard can provide a clear and reliable reference for all kinds of collection units, promote the unification of classification methods of TCM ancient books, and promote the sharing and utilization of TCM ancient books.

Objective To investigate the nutritional status of the pupils with cerebral palsy and the factors related with nutrition. Methods The height and weight of 139 cerebral palsy pupil (6~18 years old) were measured. The rate of stunting, wasting, overweight and obesity were calculated, and compared with the norm, and among the subjects with different cerebral palsy type, grade of Gross Motor Function Classification System (GMFCS), famiy background (urban or rural), age, etc. Results The rate of stunting and wasting was more than the norm, and the obesity was less. The rate of stunting negatively correlated with the grade of GMFCS. The rate of wasting negatively correlated with the age. Conclusion It is important to focus on the physical development delay and malnutrition of children with cerebral palsy.

Objective To observe the development of Traditional Chinese Medicine health maintenance books in the past. Method Based on the General Catalogue of Traditional Chinese Medicine Ancient Books, the author did a bibliometrics analysis from the year of the ancient literature of the TCM health preservation, the year and type of the version, the distribution of the second class of the health maintenance, the unique books of ancient books in health maintenance, the collection in the series and Collected Taoist Scriptures and other issues. Results Of the 551 kinds of works of health maintenance embodied in the General Catalogue of Traditional Chinese Medicine Ancient Books, 404 kinds were completed before 1911, including 3 in the Han Dynasty, 1 in the Three Kingdoms Period, 2 in the Eastern Jin Dynasty, 1 in the Northern and Southern Dynasties, and 23 in the Tang Dynasty, 16 in the Song Dynasty, 20 in the Yuan Dynasty, 155 in the Ming Dynasty,and 183 kinds in the Qing Dynasty. The distribution of edition year was 1 in the Yuan Dynasty, 155 in the Ming Dynasty, 182 in the Qing Dynasty, 155 in the Republic of China, and 47 unknown. The versions were mainly wood-block edition, lithograph, stereotype edition, manuscript, and copied manuscript. There were different types of second class, including 309 kinds of general theory of health-maintenance, 157 kinds of Daoyin and Qigong, and 85 kinds of alchemy. There were 224 kinds of unique books, accounting for 40.65％ of the total amount of 551 kinds of books of traditional Chinese medicine, among which 95 kinds were included in the series, and 109 kinds were included in Collected Taoist Scriptures, Quotes of Taoist Canon, Taoist Essence, and Taoist Collection. Conclusions The Health monographs reflect the development of TCM health maintenance level, the ideological culture, and social changes in different historical periods, which is of great value in the history of TCM health maintenance.

Objective:The data mining method was used to analyze the medication rules of the ancient prescriptions for yin deficiency syndrome, so as to provide reference for clinical treatment of yin deficiency syndrome.Methods:We searched the database of ancient prescriptions, selected the prescriptions for yin deficiency syndrome, used the Ancient and Modern Medical Case Cloud Platform V2.2.3 to count the frequency and attribute of drug use, and carried out hierarchical cluster analysis to find the core prescription. MATLAB was used to analyze the association rules, and the law of drug compatibility was found. The Pajek64 5.13 was used for complex network analysis to find out the core traditional Chinese medicine.Results:There were 467 prescriptions that meet the requirements, 302 kinds of drugs were used in total. The four properties of the drugs were mainly cold, the five flavors mainly sweet, the meridian of the drugs mainly kidney meridian. The core drugs were Rehmanniae Radix Praeparata, Ophiopogonis Radix, Rehmanniae Radix, and Poria. The most commonly used drug pair was Dioscoreae Rhizoma- Rehmanniae Radix Praeparata, the second was Corni Fructus- Rehmanniae Radix Praeparata, Poria-Rehmanniae Radix Praeparata. The commonly used drugs can be clustered into two categories. Conclusion:We can preliminarily reveal that the ancient medication law of yin deficiency syndrome is mainly nourishing Yin liquid and reducing fire, paying attention to nourishing kidney yin, using Yin nourishing medicine often combined with medicine of tonifying lung, liver, spleen yin and diverging to reduce fever. It can provide certain reference for clinical treatment of yin deficiency syndrome.

The standardization of classification methods of Traditional Chinese Medicine(TCM) ancient books can provide a clear and reliable reference for all kinds of TCM ancient books collection units, which can also promote the sharing and utilization of TCM ancient books. We studied and investigated the classification methods of TCM ancient books in past dynasties. The standard on classification of TCM ancient books was formulated by compared with the classification table of Zhongguo Zhongyi Guji Zongmu, and referred to the classification table of Zhonghua Guji Zongmu. This standard specified three-level categories and classification principles of TCM ancient books, and mainly composed of basic categories, three-level category table, classification principles and examples, and instructions for use.