Objective To explore the effect of straddling chair on paraplegic patients complicated with pressure sore. Methods Nineteen paraplegic patients complicated with pressure sore were set as the control group where they were managed with routine rehabilitation training and adapted negative pressure drainage at the sore.Another twenty-three paraplegic patients complicated with pressure sore were set as the experiment group where conventional rehabilitation trainings was taken and besides the patients were managed with rehabilitation training by riding on the straddling chairs.The curative effect of pressure sore and the activities of daily living(ADL)at discharge were compared between the two groups.Result The experiment group was significantly better than the control group in terms the curative effect,time for discharge and ADL(all P<0.05).Conclusion Rehabilitation training of paraplegic patients’riding on the straddling chair may be helpful for the improvement of the activities of ADL and effective prevention and curative treatment of the pressure sore.

Objective To investigate the relationship between diffusion time and diffusion tensor-derived parameters. Method Diffusion tensor data sets were obtained from 11 healthy volunteers using 8 different levels of diffusion time while keeping the diffusion sensitive gradient magnetic field strength fixed. Diffusion tensor-derived parameters with variant diffusion time for six regions of interest were calculated and compared. Result There was statistically significant difference in mean diffusivity (MD) of variant diffusion time (P0.05). Conclusion There is no diffusion time dependent in FA, but MD are diffusion time dependent. The reason may be attributed to the difference of the diffusion properties between the intra- and extra-cellular water molecules.

Seven new 4-hydroxybenzyl-substituted amino acid derivatives (1-7), together with 11 known compounds, were isolated from an aqueous extract of the rhizomes of Gastrodia elata Blume. Their structures were determined by spectroscopic and chemical methods. Compounds 1-3 are pyroglutamate derivatives containing 4-hydroxybenzyl units at the N atom and 4-7 are the first examples of natural products with the 4-hydroxybenzyl unit linked via a thioether bond to 2-hydroxy-3-mercaptopropanoic acid (4-6) and 2-hydroxy-4-mercaptobutanoic acid (7), which would be biogenetically derived from cysteine and homocysteine, respectively. The structures of 1 and 2 were verified by synthesis, while the absolute configurations of 4, 5 and 7 were assigned using Mosher's method based on the MPA determination rule of Δδ RS values. The known compound 4-(hydroxymethyl)-5-nitrobenzene-1,2-diol (8) exhibited activity against Fe(2+)-cysteine induced rat liver microsomal lipid peroxidation with IC50 values of 9.99×10(-6) mol/L.