1.Analysis of the risk factors for post-operative respiratory failure in elderly cardiac carcinoma patients
Lifan ZHANG ; Huaihong XU ; Minjie YANG ; Huibiao ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2010;17(11):1496-1498
Objective To analyze the risk factors of post-operative respiratory failure in elderly cardiac carcinoma patients.Methods 28 elderly patients with respiratory failure (respiratory failure group) after the resection of cardiac carcinoma and 56 controls (control group) were studied.Preoperative respiratory function,the other complications,the site of incision,intravenous infusion,age of patients and smoking between two groups were compared by Logistic regression.Results Univariate risk factors included MVV<50% ,RV/TLC>50% ,FEV1<1.5L,PEF<70% ,DLCO<80% ,V75<70% ,the venous input,incision at chest.Multivariate logistic regression analysis identified that MVV<50% ,RV/TLC>50% ,FEV,<1.5 L,DLCO<80% were risk factors.Conclusion These results suggested that the patients with risk factors described above need more careful pre and post operative surveillance and management.
2.Changes of matrix metalloproteinase-3 and urokinase-type plasminogen activator receptor in type 2 diabetes mellitus with macroangiopathy
Lei XU ; Xingguo LU ; Huaihong CHEN ; Haiya FU ; Xiaoli LIN ; Qihui JIN
Chinese Journal of Pathophysiology 1989;0(05):-
AIM: To investigate the function of matrix metalloproteinase-3 (MMP-3) and urokinase-type plasminogen activator receptor (uPAR) to macroangiopathy in type 2 diabetes mellitus. METHODS: The levels of MMP-3 and uPAR in plasma were determined by ELISA sandwich method in 26 healthy controls and 39 patients with type 2 diabetes mellitus including 15 complication-free cases and 24 with macroangiopathy. RESULTS: The plasma level of uPAR but not MMP-3 was higher in patients without macroangiopathy than that in normal controls (P
3.An 11-site cross-section survey on the prevalence of nutritional risk, malnutrition (undernutrition) and nutrition support among the diagnosis-related group of elderly inpatients younger than 90 years old with coronary heart disease in North and Central China
Jingyong XU ; Yan WANG ; Puxian TANG ; Mingwei ZHU ; Junmin WEI ; Wei CHEN ; Huahong WANG ; Yongdong WU ; Xinying WANG ; Li ZHANG ; Suming ZHOU ; Jianqin SUN ; Birong DONG ; Yanjin CHEN ; Huaihong CHEN ; Huiling LOU
Chinese Journal of Clinical Nutrition 2018;26(3):149-155
Objective To investigate the prevalence of nutritional risk,undernutrition and nutritional support among elderly inpatients with coronary heart disease in 11 tertiary A hospitals in China.Methods Records of elderly patients under the age of 90 with coronary heart disease were collected between March 2012 and May 2012 from 11 tertiary A hospitals in China following the direction of diagnosis related group of Beijing government.Results A total of 1 279 consecutive cases were recruited with the average age 74 years old (65-89).The total nutritional risk prevalence was 28.14% (360/1 279).The prevalence of nutritional risk and nutritional risk score ≥ 5 increased with age.The prevalence of nutritional risk (12.88% vs.30.08% vs.42.28%) and nutritional risk scored ≥5 (10.86% vs.18.61% vs.27.78%)increased with age.Judging from BMI,most patients were overweight or obese (BMI ≥ 24 kg/m2),accounting for 53.0% of the total,and prevalence of nutritional risk in this subgroup was 15.12% (96/635).The prevalence of nutritional risk in patients with normal BMI was 34.24%.The prevalence of undernutrition defined as BMI< 18.5 kg/m2 was 4.25% (51/1 279),among which patients with score ≥ 5 account for 64.7% (33/51).The prevalence of undernutrition defined as nutritional impairment score =3 was 7.58% (97/1 279).In patients with nutritional risk,57 were administrated nutrition support (16.6%);in patients without nutritional risk,21 received nutrition support,mostly parenteral nutrition (16 cases,76.2%).In patients with nutritional risk [(79.46± 7.19) years vs.(76.40± 6.16) years],there were statistically significant difference between those who received nutrition support and those who did not in terms of age and the ratio of patients with nutritional risk scored≥5 (35.1% vs.17.1%) (P =0.001,P=0.002).Conclusions The prevalence of nutritional risk in patients with coronary heart disease was high.The prevalence of undernutrition was low.Prevalence of overweight and obese was high,but there was still nutritional risk in this group of patients.The patients who received nutrition support were older and had high nutritional impairment score,but the indication is not rationale.