1.Clinical Analysis of the Selective Uterine Arterial Embolization in Treating Uterine Leiomyoma
Yi ZHANG ; Huaifang LI ; Yi LI
Journal of Chinese Physician 2001;0(02):-
Objective To analyze the clinical data of selective uterine arterial embolization in treating uterine leiomyoma retrospectively. Methods Super-selective arterial embolization were performed using Seldinger's technique. The degree of shrinkage of uterine and leiomyoma were measured, and the influence of the treatment on ovarian function was analysed as well. Results After embolization, uterine and leiomyoma significantly shrinked. Uterine leiomyoma artery embolization(UAE) had no influence on ovarian function. Conclusions UAE is an effective method in treating uterine leiomyoma.
2.Clinical analysis of 37 cases of pneumoconiosis treated with combination of Chinese and western medicine
Xiaojue SU ; Huaifang FAN ; Li WANG
Chinese Journal of Primary Medicine and Pharmacy 2017;24(19):2881-2884
Objective To explore the curative effect and prognosis of traditional Chinese medicine combined with western medicine in the treatment of silicosis patients.Methods 74 patients with silicosis were selected as the research subjects.According to the admission time,the patients were divided into the observation group and the control group,37 patients in each group.The control group was treated with conventional western medicine,the observation group was given the combined treatment of traditional Chinese medicine and western medicine.The clinical curative effect,pulmonary function index,symptoms improved time and the reduce of lung shadow were observed and compared.Results The reduction rate of lung shadow in the observation group was 75.67%,which in the control group was 62.16%,there was statistically significant difference between the two groups (u =2.419,P =0.015).The total effective rate of the observation group was 86.49%,which of the control group was 67.57%,there was statistically significant difference between the two groups (u =2.116,P =0.034).After treatment,the vital capacity (VC),forced vital capacity(FVC) and the first second forced expiratory volume (FEV1) in the observation group were (69.15 ± 18.34)%,(71.08 ± 16.93)%,(68.91 ± 18.75)%,respectively,which in the control group were (63.37 ± 20.53) %,(63.13 ± 18.69) % and (55.47 ± 17.58) %,respectively,which in the two groups were higher than those before treatment,which in the observation group increased significantly,there were statistically significant differences between the two groups (t =6.778,P =0.000,t =8.836,P =0.000,t =10.133,P =0.000).The wheezing,cough,pulmonary rales and other symptoms improved time in the observation group were shorter than those in the control group,the differences were statistically significant (t =8220,P =0.000,t =6.836,P =0.000,t =6.909,P =0.000).Conclusion Traditional Chinese medicine combined with western medicine in the treatment of silicosis has higher reduction rate of lung shadow,lung function improved significantly,shorter improved time of cough,wheezing and other symptoms,its curative effect is better than western medicine.
3.Impact of cryopreservation on CM-Dil labeled human umbilical cord mesenchymal stem cells
Yan CHEN ; Jianjun WANG ; Huaifang LI
International Journal of Biomedical Engineering 2014;37(4):-
Objective To observe the feasibility of labeling human umbilical cord mesenchymal stem cells (hUCMSCs) with chloromethyl-benzamidodialkylcarbocyanine (CM-Dil) and the influence of cryopreservation on the CM-Dil labeled hUCMSCs.Methods Using tissue explant to culture hUCMSCs,the morphology and growth situation of the cells were observed,and cell phenotype were identified by flow cytometry.The cells of the 3rd generation were labeled with CM-Dil.The cell morphology,growth situation and fluorescent markers were observed under fluorescent microscope.The labeled cells were cryopreserved and recovered,and the growth of cells and its fluorescent labeling conditions were observed after recovery.Results The morphology of hUCMSCs was similar to fibroblasts,spindleshaped and polygonal.The cells of the 3rd generation of hUCMSCs strongly expressed CD44,CD29,CD90 and CD73,but did not express CD34 and CD45.The mark rate of CM-Dil to label hUCMSCs reached as high as 90% and the dye was mainly in the cell membrane.The labeled cells are in good condition and the cells after cryopreservation and recovery still have strong fluorescence expression,also the cell growth is in good condition.Conclusions Using CM-Dil to label and track hUCMSCs is simpler than other methods.Cryopreservation does not have negative influence on CM-Dil-labeled hUCMSCs.
4.A comparative study on two surgical procedures in treatment of stress urinary incontinence in old women
Xinliang CHEN ; Min JIANG ; Li FENG ; Huaifang LI ; Xiaowen TONG
Chinese Journal of Geriatrics 2010;29(8):648-651
Objective To evaluate the safety and efficacy of two surgical procedures including retropubic space pathway and obturator foramen pathway in treatment of the old women with stress urinary incontinence (SUI). Methods Intravaginal Slingplasty (IVS) procedure by retropubic space pathway was performed in 52 cases with simple SUI from June 2003 to June 2005. And the modified Transobturator Vaginal Tape Inside-Out (TVT-O) procedure was carried out in 112 cases with simple SUI from October 2005 to October 2008, using self-tailed polypropylene mesh and helical needles. The comparative retrospective study was performed between these two groups. Results The cure rate was 80.8% (42/52) and the improvement rate was 13.5% (7/52) in IVS group. And the corresponding data were 84.8% (95/112) and 11.6% (13/112) in modified TVT-O group. The 3 (5.8%) cases failed in IVS procedure and 4 (3.6%) cases failed in modified TVT-O procedure at 1 month's follow-up. All of the 7 patients received the 'Tong's hammock procedure' and no cases failed at 6 and 12 month's follow-up. One case of vaginal erosion was found in each group although good effect of continence was observed. Meshes were removed in these two patients and then the 'Tong's hommock procedure' was performed which turned out to be good outcome. Bladder injuries were found in 3 cases when route cystoscopy was performed. No significant difference in efficacy was found between these two groups(P>0. 05). In modified TVT-O group, operative duration, blood loss and medical cost were significantly reduced as compared with IVS group (P<0. 01). Conclusions Both of the two surgical procedures of modified TVT-O versus IVS are simple, safe and mini-invasive procedures with high efficacy. However, the modified TVT-O procedure is more easy to be adopted by patients due to short operative time and lower medical cost.
5.Application of modified total pelvic reconstruction in the treatment of pelvic organ prolapse in elderly women
Xinliang CHEN ; Min JIANG ; Jun QIU ; Huaifang LI ; Xiaowen TONG
Chinese Journal of Geriatrics 2014;33(1):66-69
Objective To evaluate the efficacy and safety of modified total pelvic reconstruction for pelvic organ prolapse in elderly women.Methods 105 patients required operation for treatment of pelvic organ prolapse were enrolled in this study.Patients were divided into experimental group (n =68,treated with the modified total pelvic reconstruction) and control group (n=37,receiving prolift procedure).Objective indexes including bleeding volume,operative time,residual urine volume,postoperative complications,medical expenses,hospitalization time were recorded.Clinical efficacy and follow-up results were recorded and compared between the two groups at 6 months after operation.Results Bleeding volume and hospitalization costs were lower in experimental group than in control group (both P<0.05),while the operative time,residual urine volume,time out of bed,anal exhaust time,the maximum body temperature,mean postoperative hospital stay showed no significant differences between the two groups (all P>0.05).Vaginal perforation was observed in 7 cases,with 4 cases in experimental group and 3 cases in control group.No serious complications such as bladder and rectum perforation were observed.According to pelvic organ prolapse quantitation (POP-Q) score,64 cases (94.1%) were cured and 4 cases (5.9%) were invalid in experimental group,while 36 cases (97.3%) were cured and 1 case (2.7%) was invalid in control group.The noninferiority test showed that clinical efficacy in experimental group was non-inferior to that in control group (u=2.252,P<0.05).Conclusions Modified total pelvic reconstruction is an effective and safe minimally invasive surgery,which is similar to prolift surgical operation,but it is relatively inexpensive,which is easier to be accepted by Chinese patients,with a great perspective in clinical application.
6.An modified vaginal mesh procedure for the female persistent or recurrent stress urinary incontinence after initial synthetic mid-urethral slings operation
Hong XIA ; Huaifang LI ; Xiaowen TONG ; Bozhen FAN
Chinese Journal of Urology 2013;(7):533-537
Objective The aim of study is to evaluate the efficacy of a new complementary midurethral sling surgery in treating recurrent or persist female stress urinary incontinence (SUI) after primary Synthetic mid-urethral slings (MUSs).Methods The methods was used in 32 patients who had suffered recurrent or persist SUI patients after primary MUSs during June 2005 and July 2011.Their primary MUSs were:TVT 2 cases,IVS 4 cases,TVT-O 17 cases,TOT 3 cases,T-sling 1case,other MUSs 5 cases.9 cases complained SUI symptoms continued after primary surgery and had no improvement after 6 months following up.23 cases reported SUI symptoms recurrent and aggravated in 6 months after primary operation and had no improvement 1 year after operation.All these patients have been treated with surgery,a trans-vaginal mid-urethral sling on descending pubic ramus.In this study we followed up these patients for one year after this complementary operation and evaluated operating time,blood loss,efficacy and complications.Results In this study the operating time was 41.1±13.1 minutes,blood loss was 70.6±23.8 ml.30 patients kept urinary catheter 6 h after operation and 2 kept urinary catheter 48 h after operation.All patients could micturate after removed urinary catheter and average residual urine was 23.8 ± 21.4 ml (range 0-80 ml).The average in-patients duration was 4.8± 1.1days.SUI symptoms still persisted in two patients after second operation,subjective cure was achieved in 26 patients and the symptoms obviously improved in 4 patients when they left hospital.The efficient rate was 93.8% (30/32) left hospital and after 3 months,93.3% (28/30) after 6 months and 86.2% (25/29) after 1 year.There were 2 cases of recurrence and 1 case of mesh erosion after 1 year,no other operative complications were reported.Conclusions Our study found that it is a efficient operation to treat SUI recur or persist after primary.