1.Measuring balance in stroke patients with tetra-ataxiametry and clinical balance scales
Huai HE ; Guiying DAI ; Chuandao LIU
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(2):134-136
Objective To compare balance assessment with static balance measuring equipment and clinical balance measuring scales. Methods Seventy hemiplegic stroke patients ( the patient group) and 36 healthy volunteers (the controls) were recruited. Each subject's equilibrium was measured using the Berg Balance Scale (BBS) ,the Fugl-Meyer Balance Scale (FM-B) and tetra-ataxiametry, all by the same therapist. Results The BBS and FM-B results both showed significant differences between the patient group and the control group. The data obtained through tetra-ataxiametric assessment showed that the average weight distribution index ( WDI ) and stability index (SI) were significantly lower in the patient group than among the controls. There was a strong correlation between the tetra-ataxiametric assessment results and the clinical balance test outcomes. The WDI and SI from tetra-ataxiametry were strongly correlated with Berg total static scores. Conclusions Tetra-ataxiametry and the BBS and FM-B tests can all effectively reflect the equilibrium of stroke patients. Tetra-ataxiametry can measure balance ability quantitatively, while the clinical balance tests ( BBS, FM-B) are easier to conduct.
2.Venous Thromboembolism in Rehabilitation: 7 Cases Report
Chuandao LIU ; Huai HE ; Weixin YANG
Chinese Journal of Rehabilitation Theory and Practice 2013;19(4):387-389
Objective To strengthen physiatrist's knowledge of diagnosis and treatment of venous thromboembolism by analysing 7 venous thromboembolic events in rehabilitation. Methods 7 cases with venous thromboembolism (VTE) in our department were involved in this study. Related data of these patients were collected, investigated and analyzed. Results 6 cases were deep venous thrombosis (DVT), 1 case was pulmonary embolism (PE). The patients with DVT were treated successfully by thrombolytic and/or anticoagulant therapy as well as later rehabilitation treatment, and the patient with PE was cured after intra-arterial mechanical thrombolysis therapy and later anticoagulant therapy. Conclusion Prevention and treatment of VTE is becoming a very important issue in development in our country. Active prevention, early recognition and treatment are very important for the prognosis of patients with VTE.
3.Effects of electromyographic biofeedback training on psychological and motor functioning in patients with spinal cord injury
Huai HE ; Guiying DAI ; Yue LIU ; Haibo WANG
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(10):762-765
Objective To investigate the therapeutic effects of electromyography biofeedback (EMGBF) on motor and psychological function in patients with spinal cord injury (SCI).Methods Seventy SCI patients were randomly divided into research and control groups with 35 patients in each.In addition to conventional rehabilitation,the patients in the research group received EMGBF training while those in the control group were treated with medium frequency electrotherapy.To evaluate the patients' self confidence and motor function of their paralyzed limbs,Rosenberg's self-esteem scale (RSES) and American Spinal Injury Association (ASIA) locomotor function scoring were performed before and six weeks after the interventions in both groups of patients.The changes of EMG of the quadriceps,hamstring and anterior tibial muscles of both groups in maximum contraction were also observed before and six weeks after the interventions.Results There were no significant differences in the RSES scores or ASIA locomotor function results between the groups before the interventions.ASIA locomotor function evaluation scores increased significantly in both groups after the interventions,with significantly better results in the research group.The RSES scores in the research group also improved significantly after the interventions,and RSES scoring and ASIA scoring were positively correlated in those patients.But no significant improvement in average RSES scores was found in the control group.The muscle contraction EMG amplitudes also increased significantly in patients of the research group after the interventions.Conclusions EMGBF training can enhance patients' self-confidence,which helps patients with SCI improve their motor functions.
4.Effects of motor imagery therapy combined with electromyographic biofeedback on upper limb function in hemiplegic stroke patients
Hongjun ZHU ; Huai HE ; Chuandao LIU ; Weixin YANG
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(6):443-446
Objective To study the effects of motor imagery therapy combined with electromyographic (EMG) biofeedback on upper limb function in hemiplegic patients.Methods Sixty hemiplegic stroke patients were recruited and divided into a control group (n=20),an electrical stimulation group (n=20) and a combination group (n=20).All groups received basic medication and routine rehabilitation training once daily for 4 weeks.The electrical stimulation group was also treated with EMG biofeedback,and the combination group with motor imagery therapy plus EMG biofeedback.The Fugl-Meyer assessment (FMA),the modified Barthel index (MBI) and EMG parameters were assessed before and after 2 courses of treatment.Results After 8 weeks of treatment all groups had significantly higher FMA scores and MBI scores,and better integrated EMG values,but the effects in the combination group were significantly better than those in the other two groups.Conclusions Motor imagery therapy combined with EMG biofeedback can more effectively promote recovery of upper limb function in hemiplegic stroke patients.
5.A clinical study on segmental instability of the lumbar spine
Weixin YANG ; Jia ZHANG ; Huai HE ; Yunqiang ZAN
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(12):-
Objective To explore factors related to the development of segmental instabilities in lumbar spine. Methods Fifty-seven patients with lumbar segment instabilities at L 4~5 were selected as illness group, 22 patients with facetectomy at L 4~5 as post-operation control group, and 19 healthy subjects as normal control. X-ray plain films were taken in sagittal,flexion and extension positions. Computed tomographic scans were taken to define the axial morphology of the facet joint. Magnetic resonance scans were taken to describe disc degeneration of 36 patients in illness group. Results The facet joint was oriented sagittally in the forward translation patients in flexion. The disc degeneration was slight in the rotational instability patients. The patients with total facetectomy exited forward translation in flexion. Conclusion A more sagittally oriented facet and disc degeneration are associated with forward translation in flexion and may be the cause of degenerative spondylolisthesis, whereas ligament failure is associated with rotational instability.
6.Effect of exercise on expression of p38 after cerebral infarction in rats
Zishan JIA ; Yaping HUAI ; Jinping ZHAI ; Chunnian HE
Chinese Journal of Rehabilitation Theory and Practice 2005;11(11):915-916
ObjectiveTo study the effect of exercise on expression of p38 after cerebral infarction in rats.MethodsThe right middle cerebral artery was occluded(MCAO) with electric coagulation in Wistar rats,and then were divided into three groups at random 48 hours later: training group which were given wheel-running exercise everyday(n=20);control group(n=20) and sham group(n=10).The expression of p38 in cortex of the three groups were detected on 7th,14th,21th and 28th day after the MCAO.ResultsIn the cortex around the infarcted focus,the expressions of p38 elevated much significantly after cerebral infarction(P<0.05).The expression of p38 in training group were higher than those in control group(P<0.05) on the 21th and 28th day.ConclusionThe cerebral infarction could induce the expression of p38.The exercise could enhance its expression.
7.STUDY ON PHYSIOLOGICAL AND BIOCHEMICAL PROPERTIES OFα-ACETOLACTATE DECAROBOXYLASES FROM DIFFERENT MICROBES
Xiuping HE ; Wenhui HUAI ; Wenjie GUO ; Borun ZHANG
Microbiology 2001;28(2):18-21
The enzyme activity of α-Acetolactate Decaroboxylases (ALDC)from different microbes was studied, the results demonstrated that it was quite different among them. There were diversities of their enzyme reaction velocities. It was clear that the enzyme activity was affected by the pH of the enzyme reaction system, for example, the optimum pH of ALDC from Lactococcus lactis was 6.6, while for Aerobacter Aerogenes it was 5.8. Addition leucine,valine and isoleucine into enzyme reaction system obviously affected the enzyme activity of ALDC from different microbes.
8.Online health information behaviors of community residents in Baiyun District, Guangzhou, China
Xuefang HE ; Yanan YU ; Pan HUAI ; Ping GU
Chinese Journal of Medical Library and Information Science 2016;25(3):59-63
Objective To investigate the access to online health information in community residents.Methods The online health information behaviors in residents of 10 communities in Baiyun District, Guangzhou, China, were in-vestigated with questionnaires and analyzed by SPSS 19 .0 .Results Of the community residents included in this in-vestigation, 25%were positive in access to online health information on general gate website and commercial health information service website, 74.34%showed their concern for food safety information, 52.30%focused their con-cern on disease symptom information, and 66.79%were unable to differentiate true information from false informa-tion.Conclusion The community residents have a low positivity and lack of awareness in access to online health in-formation.It is thus pressingly necessary to build the government-dominated online health information platform, and improve the commercial network model and the ability of community residents to differentiate true information from false information.
9.Effect of small direct-current electrical stimulation on migration and invasion related MMPs/TIMPs expression of trophoblast cells
Juan ZHANG ; Mingyong LI ; Yuan HE ; Huai BAI ; Ping FAN
Chongqing Medicine 2016;45(7):869-872
Objective To investigate the effect of small direct‐current electrical stimulation on migration and invasion related MMPs/TIMPs expression of trophoblast cells .Methods The trophoblast cells were exposed to the direct current electrical field at 150 mV/mm for 5 and 10 hours .Cell images were recorded with continuous photographing and analyzed by image analyzer .The ex‐pression levels of MMP2 ,MMP9 ,TIMP1 and TIMP2 were measured using quantitative RT‐PCR and Western blot .Results In non‐electrical field culture trophoblast cells migrated slowly with random directions .Trophoblast cells cultured in media containing 10% calf serum with the application of 150 mV/mm direct current electrical stimulation ,showed marked cathodal migration (P<0 .01) ,the cell body stretched ,perpendicular to the direction of the electric field .Compared with the non‐electrical field stimulation controls ,trophoblasts under the electrical field stimulation had the increased MMP2 mRNA and protein expression (P< 0 .05) , while MMP9 ,TIMP1 and TIMP2 had no obvious changes of mRNA or protein expressions .Conclusion Physiological direct‐cur‐rent electrical fields might induce directed migration and perpendicular orientation of trophoblast cells .The enhanced MMP2 expres‐sion may play an important role in the migration and invasive activity of trophoblast cells in small electrical field .