1.Roles of nitric oxide and K~+ channels in urocortin-induced relaxation on SHR thoracic aorta
Hongyi WANG ; Jie CHEN ; Huae XU ; Jin TAO ; Shengnan LI
Chinese Pharmacological Bulletin 2003;0(10):-
Aim To investigate the vasodilatory effect and the mechanisms of urocortin(Ucn) on the thoracic aorta of spontaneously hypertensive rats(SHR).Methods Rings cut from SHR thoracic aorta were used in vitro.The endothelium dependent and independent vasorelaxing effects of Ucn were measured.Furthermore,it was also explored whether the relaxing effects of Ucn were affected by N~((?)) nitro-L-arginine methyl ester(L-NAME), methylene blue(MB) and glybenclamide.Results Ucn(1 nmol?L~(-1)~1 ?mol?L~(-1)) caused concentration dependent relaxation in SHR thoracic aorta with endothelium and without endothelium(P
2.Construction and reflection of mixed evaluation system of physiology
Wenli MAI ; Ce XU ; Ying GAO ; Yuanyuan ZHOU ; Xinghai LIU ; Tuanxiao ZHANG ; Huae JING ; Jiewei LUO
Chinese Journal of Medical Education Research 2023;22(2):208-211
The mixed evaluation system uses the network platform as a carrier to construct a dynamic evaluation model that spans time and space between online and offline, between individuals and teams. Mixed evaluation system of physiology was performed for two years, and the process evaluation and the summative evaluation in the mixed evaluation system showed a good correlation, and the students' learning ability and learning effect showed consistency with the evaluation results. Practice has proved that the mixed evaluation system not only optimizes the traditional evaluation system, but also fully expands the five principles of formative evaluation; however, while reflecting the advantages of the network platform, it also exposes the defects of insufficient supervision of the network platform. Thus, we should further improve the mixed evaluation system of physiology.