1.The research on humanities education of medical postgraduates
Chinese Journal of Medical Education Research 2011;10(6):690-692
This article found that the actual situation about humanities education of medical postgraduates is not optimistic through investigation of the situation on humanities education of the postgraduates in Zunyi Medical College. Some prominent problems existed. This article also proposed some practical suggestions to solve the problems based on the analysis of this phenomenon, so as to improve the humanities education of medical postgraduates and cultivate postgraduates to be medical workers with full humanistic care.
3.Thought on development of minimally invasive gastrointestinal surgery in China.
Chinese Journal of Gastrointestinal Surgery 2012;15(8):765-767
Laparoscopic surgery for gastrointestinal diseases had a remarkable progress in the past 20 years. Laparoscopic surgery for colon cancer is adopted worldwide by increasingly surgeons based on the evidence from randomized controlled studies. Minimally invasive surgery is also adopted as alternative procedure for early gastric cancer. The standardization and spreading of the minimally invasive technique for gastrointestinal surgery is also being implemented efficiently in China. However, how to innovate the new technique and improve the new instrumentation for minimally invasive surgery is still a problem which we have to confront in the current situation. But we believe that with the great efforts of gastrointestinal surgeons, the widespread adoption of minimally invasive gastrointestinal surgery would surely take place in the near future.
China
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Female
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Gastrointestinal Tract
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surgery
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Humans
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Laparoscopy
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methods
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Male
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Minimally Invasive Surgical Procedures
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methods
7.Research progress on the topical use of triamcinolone in the treatment of oral mucosal diseases
Journal of Practical Stomatology 2015;(2):278-281
A total of 21 papers about topical use of triamcinolone in the treatment of oral diseases were retrieved.1 7 of the 21 papers were about the treatment of oral lichen planus,3 were about recurrent aphthous ulcer and 1 was about Behcet's Syndrome.Topical use of triamcin-olone,either used alone or combined with other drugs,was effective in the treatment of oral lichen planus,recurrent aphthous ulcer and Beh-cet's Syndrome.No adverse drug reaction happened when triamcinolone was used in the patients after a short time application,while it hap-pened in the patients after prolonged-use.It may be also effective in the treatment of other allergy or immune dysfunction related oral mucosal diseases,of which more research should be carried out.
8.Changes of Th17 positive splenocytes and retinal interleukin-17 expression in rats with traumatic optic neuropathy
Chinese Journal of Experimental Ophthalmology 2015;33(10):876-880
Background Studies showed that traumatic optic neuropathy (TON) can activate and induce immuno-inflammatory response,while T helper cell 17 (Th17), a CD4+ T lymphocyte, is associated with immunoinflammatory response.However,the effects of Th17 on the development of TON are unclear.Objective This study was to observe the changes of Th17 lymphocytes in spleen and the expression of interleukin-17 (IL-7) in retina in TON rats.Methods Seventy male 4-week-old SD rats were randomly divided into normal control group, sham operation group and TON 1-, 3-,7-, 14-and 28-day group according to random number table.The optical nerves of the right eyes were exposed and impacted at a 25° angle by using fluid percussion injury (FPI) device with the average force (699.1±60.8) kPa to create the TON models in the TON groups,and only optical nerves were exposed in the sham operation group.Flash visual evoked potential (F-VEP) was recorded and the amplitude and latency were measured to evaluate the function of optical nerves of the rats.The rat splenocyte suspension in various groups was prepared for the detection of Th17 cells by flow cytometry, and the expression of IL-17 protein was detected by immunochemistry.Results No significant differences were found in the amplitudes and latencies of P2 wave, proportion of Th17 cells and the IL-17 positive cell numbers in retina between the normal control group and sham operation group (P =0.829,0.830,0.856,0.496).The amplitudes of P2 wave were significantly lower, and the latencies of P2 wave were significantly longer in the TON groups than those in the sham operation group (all at P< 0.05).The proportions of Th17 positive CD4+ T lymphocytes were (0.94±0.13)%,(1.80±0.18)%,(1.98± 0.20)% ,(2.34±0.20)% ,(2.11±0.13)% ,(1.92±0.18)% in the sham operation group,TON 1-day group,TON 3-day group,TON 7-day group,TON 14-day group and TON 28-day group, respectively, showing significant differences between the sham operation group and various TON groups (all at P<0.05).In addition, the IL-17 positive cell numbers in retina were 796.326 ± 100.028, 1 673.416 ± 188.021,1 892.431 ± 151.026,2 420.454 ± 256.024,1 996.429±177.022 and 1 629.410±127.023 in the sham operation group,TON 1-day group,TON 3-day group,TON 7-day group,TON 14-day group and TON 28-day group, respectively, showing significant differences between the sham operation group and various TON groups (all at P<0.05).Conclusions In rats of TON, the proportion of Th17 cell in splenocytes and the expressions of IL-17 in retina are increased,suggesting that Th17 and IL-17 participate in the progression of TON.
9.Relationship between meso-hippocampal dopaminergic projections and hippocampal P300-like potentials in rats
Chinese Journal of Pathophysiology 2000;0(10):-
AIM: To evaluate the role of the meso-hippocampal dopaminergic systems in the generation of hippocampal P300-like potentials. METHODS: Changes of ventral hippocampal P300-like potentials were examined after lesions of the meso-hippocampal dopaminergic systems.The extracellular DA and DOPAC were collected by the push-pull method in the ventral and dorsal hippocampus and their contents were measured by high-performance liquid chromatography with electrochemical detection(HPLC-EC). RESULTS: The contents of DA and DOPAC in the ventral hippocampus were higher than those in the dorsal hippocampus in the normal animals. The peak latencies of P300-like potentials were prolonged and the contents of DA and DOPAC decreased in the ventral hippocampi after lesions of the meso-hippocampal dopaminergic systems. CONCLUSIONS: There exist meso-hippocampal dopaminergic systems in rats;The meso-hippocampal dopaminergic terminals is mainly located in the ventral hippocampal area in rats; The meso-hippocampal dopaminergic projections take part in the generation of the hippocampal P300-like potentials in rats.
10.Preparation of Tretinoin Liposome by Calcium Acetate Gradient Method
China Pharmacy 2001;0(08):-
OBJECTIVE:To evaluate the feasibility of preparing tretinoin liposome by calcium acetate gradient method and to compare this method with the microfilm and the antiphase evaporation method.METHODS:Tretinoin liposome was pre-pared by microfilm method,antiphase evaporation method and calcium acetate gradient method,respectively.Sephadex G-50was used for isolation and ultraviolet spectrophotometry was utilized to determine the entrapped efficiency and grain size of liposomal tretinoin.Electronmicroscope was applied to observe the shape of tretinoin liposome.RESULTS:The calcium ac-etate gradient technology achieved the highest entrapped efficiency of90.48%.The liposomes had perfect shape with the mean diameter of35.8nm and kept stable in quality at4℃for3months.CONCLUSION:The liposome with high entrapped effi-ciency could be prepared by calcium acetate gradient method,and the method is feasible.