Assessment of minimal residual disease (MRD) in acute myeloid leukemia (AML) patients is now possible by using updated methods including real-time quantitative PCR (RQ-PCR) for abnormal fusion transcripts and multiparameter flow cytometry (MFC) for detecting leukemia-associated phenotypes.Using these techniques,MRD analysis has shown value in terms of risk assessment,continued patient monitoring,and therapeutic decision-making.

105 organisms/ml).Two weeks after the operation,all blind loop rats had no weight-gaining.Four weeks after the operation,all blind loop rats had greater mean corpuscular volume(77.9?5.7)fl vs(57.6?1.6)fl((P

Carbon-Carbon Ligases ; deficiency ; Child ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Prognosis

Cholesterol was originally identified as an element of biomembrane with a key role in the regulation of the stability of membrane. Recent researches had revealed that mortality was inversely related to cholesterol levels, and hypocholesterolemia correlated with a high risk of complication. Evidence is now accumulating that low serum cholesterol levels appear to be an independent predictor of short-term mortality.

Animals ; Biomarkers, Tumor ; analysis ; Electrophoresis, Gel, Two-Dimensional ; Humans ; Neoplasm Proteins ; secretion ; Neoplasms ; etiology ; pathology ; secretion ; Proteome ; secretion ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Acute Disease ; Adenoviridae Infections ; epidemiology ; Adolescent ; Child ; Child, Preschool ; China ; epidemiology ; Humans ; Infant ; Infant, Newborn ; Respiratory Tract Infections ; epidemiology ; virology

Child ; Child, Preschool ; Diarrhea ; virology ; Female ; Genotype ; Humans ; Infant ; Male ; Rotavirus ; classification ; genetics ; isolation & purification ; Seasons

Bacteria ; drug effects ; Communicable Diseases, Emerging ; epidemiology ; microbiology ; Drug Resistance, Bacterial

Medical molecular imaging not only promotes the development of medical imaging, but also pushes research progress of life science and benefits the amalgamation of multi-subjects in medical imaging. This editorial overviews the history and development trends of medical molecular imaging.
Humans ; Molecular Imaging ; trends

Objective To explore the effect of type 2 diabetes mellitus(T2DM) on vascular damage characteristics of acute cerebral infarction and the impact on the short term prognosis.Methods One hundred and fifty-six cases of acute cerebral infarction patients were selected and divided into the T2DM group with 64 cases and non-T2DM group with 92 examples.According to the whole cerebral angiogram,the results and the results of the treatment of acute cerebral infarction and prognosis were analyzed.Results The incidence of intracranial artery stenosis of the T2DM group was 79.69％ (51/64),of non-T2DM group was 58.70％ (54/92),the difference between two groups was significant(x2=12.856,P＜0.05).The incidence of before andafter intracranial artery stenosis coexist,circulation narrow coexist in T2DM group was 50.00％ (32/64),59.36％(38/64) respectively,in non-T2DM group was 21.74％(20/92),29.35％(27/92) respectively,the difference between groups was significant(x2 =9.652,8.659;P＜0.05).The incidence of multivessel lesions and diffuse lesions and without collateral compensatory in T2DM group was 71.88％ (46/64),65.63％ (42/64) and 71.88％(46/64) respsctively,in non-T2DM group was 54.35％(59/92),39.13％(36/92) and 31.52％(29/92) respectively,thedifference between groups was significant(x2=8.625,9.354,11.053;P＜0.05).The total effective rate after 2 weeks of treatment in T2DM group was 46.88％(30/64),in non-T2DM group was 90.22％(83/92),the difference between groups was significant(x2=8.061,P＜0.05).Conclusion The incidence of intracranial artery stenosis in patients with intracranial artery stenosis combined with T2DM is higher than the control group,and lesion range widely,diffuse damage,vascular damage moderately severe stenosis and occlusion are significantly higher than in non-T2DM group,especially without collateral compensatory rates is higher than non-T2DM group,while the neural function damage of T2DM group is heavier and poorer prognosis.