0.05). But the Wuling Sang could obviously decrease serum TG content than Simvastatin(P0.05). The adverse drug reactions were stomach discomfort(4 patiens in SWS) group, 5.71%), abdominal discomfort(2 patiens in Simvastatin group, 4.55% ) and sleeplessness(5 patiens in Simvastatin group, 11.4%) . CONCLUSION: The results show the TCM drug SWS is effective and softy on treating the patients with primary hyperlipemia.

Objective To observe the effect of laser and intubation applied in recurrent nasolacrimal duct-blok.Methods 116 cases of recurrent nasolacrimal duct-blok patients were selected and divided into the observation group and control group by random number table.Only laser was given in the control group,and intubation added in the observation group.All the cases were followed up more than 1 year,and the effects in both group were compared. Results There were 63 effective cases in the observation group,and efficacy rate was 83.33%.And 17 effective cases in the control group,efficacy rate was 41.56%.The efficacy rate in the observation group was higher than that in the control group (χ2 =31.915,P <0.05).There was no false passage in both groups after laser given.Conclusion The effect of laser combined with intubation was better than that of laser alone in recurrent nasolacrimal duct-blok treatment.It was valuable to refractory and recurrent nasolacrimal duct-blok treating.

Objective:To discuss the curative effect of atorvastatin intensive treatment on lipid-lowering in the patients with type 2 diabetes and its influence on vascular endothelial function. Methods: Totally 74 cases of patients with type 2 diabetes were selected and divided into the intensive group ( n=37 cases) and the ordinary group ( n=37 cases) at random. The patients in the two groups were given routine medical treatment, such like diet adjustment, moderate exercise and drug control etc, and the patients in the inten-sive group were additionally given 40 mg atorvastatin orally, once a day, while the patients in the ordinary group were additionally given 20mg atorvastatin orally, once a day for 12 weeks. The changes of blood fat, von willebrand factor (VWF) of serum vascular endothe-lial function, plasma thrombomodulin ( PTM) and vascular endothelial cadherin ( VEC) levels of the patients before the treatment and in the 12th week after the medical treatment were observed and compared, and the adverse drug reactions ( ADR) were evaluated as well. Results:After the 12-week medical treatment, TC, TG and LDL-C levels of the patients in the two groups were obviously de-clined than those before the treatment, while HDL-C levels were obviously raised than those before the treatment ( P<0. 05 or P<0. 01), and the changes in the intensive group was more notable than those in the ordinary group (P<0. 05). Meanwhile, serum VWF, PTM and VEC levels were obviously declined than those before the treatment (P<0. 05 or P<0. 01), and the declining rate in the intensive group was much higher than that in the ordinary group (P<0. 05). Totally 2 and 4 cases of untoward effect appeared re-spectively in the ordinary group and the intensive group with light symptom, and the incidence of ADR showed no statistical difference between the two groups (P>0. 05). Conclusion:Compared with atorvastatin, atorvastatin intensive treatment in the patients with type 2 diabetes has more favorable lipid-lowering effect, which can effectively reduce serum vWF, PTM and VEC levels to improve and rem-edy vascular endothelial function with high security.

Assessment of minimal residual disease (MRD) in acute myeloid leukemia (AML) patients is now possible by using updated methods including real-time quantitative PCR (RQ-PCR) for abnormal fusion transcripts and multiparameter flow cytometry (MFC) for detecting leukemia-associated phenotypes.Using these techniques,MRD analysis has shown value in terms of risk assessment,continued patient monitoring,and therapeutic decision-making.

Objective To understand the detection situation of Mycoplasma pneumoniae (MP)and Chtamydia trachomatis (CT) in children with respiratory tract infection.Methods MP and CT were simultaneously measured by fluorogenic quantitative PCR in 1393 children patients with respiratory tract infection.Results The total detection rates of MP and CT were 30.4%,in which MP was 21 .8%,CT was 9.3% and MP complicating CT was 0.65%.In the season distribution,the detection rates of MP and CT were highest in summer.In the age distribution,the detection rate of MP in the over 3-year-old group was higher than that in the other age groups,the differences had statistical significance(P <0.05).The detection rate of CT in the less than 1-month-old group was higher than that in other age groups with statistical difference(P <0.05).Conclusion MP and CT are easy to be detected out in summer;MP is easy to be detected out in children over 3 years old than other age groups;MP is easy to be detected out in neonates than other age groups.Fluorogenic quantitative PCR is rapid,sensitive and highly specific for the diagnosis of MP and CT infec-tions.

Objective] To observe the six taste of Yuping wind powder combined with eye wash method in the treatment of al ergic conjunctivitis AC and the clinical curative effect. [Methods] From 2008 January to 2014 June in our hospital, diagnosed with al ergic conjunctivitis in 60 patients(120 eyes), were randomly divided into three groups of 20 cases(40 eyes), had the local application of 2% Sodium Cromoglicate Eye Drops three times a day, treatment group with six kinds of Yuping Feng powder taken oral y combined with traditional Chinese medicine topical eye wash method, the control group 1 of six kinds of Yuping Feng powder taken oral y, two times a day, the control group 2 only topical eye, were treated and fol owed up for 4~6 weeks, the clinical efficacy of the three groups were compared, also the use of statistical methods for the two sets of data analysis and comparison. [Results] The treatment group and the 2 control groups total efficiency compared had a significant difference( P<0.01); the treatment group and the control group 1 of total efficiency had significant difference(P<0.05). [Conclusion] The six taste of Yuping Feng powder combined with traditional Chinese medicine eye wash method must be effective in treatment of al ergic conjunctivitis, worthy of promotion.

BACKGROUND:The clinical treatment of thoracolumbar fractures and dislocation of the patients can be treated with pedicle screw fixation through adjacent vertebral segments. With the increased incidence of disease, many problems were found such as fixator loosening and breakage. OBJECTIVE:To compare the effectiveness of vertebral pedicle screw fixation versus cross-segment pedicle screw fixation for thoracolumbar vertebral fracture and dislocation. METHODS:100 patients with thoracolumbar vertebral fracture and dislocation were chosen in the 474 Hospital of Chinese PLA from February 2013 to May 2014. The patients were randomly assigned to two groups (n=50). Patients in the control group were treated with cross-segment pedicle screw fixation, and those in the observation group were treated with the vertebral pedicle screw fixation. Parameters of imaging were compared and observed. RESULTS AND CONCLUSION: Significant differences in the spinal canal area improvement value and internal fixation failure rate were detected between the two groups (P < 0.05), and the observation group was better than the control group. The height ratio of anterior border of the vertebral body was higher at 12 months after treatment than that pretreatment, but Cobb angle was lower than pretreatment (P < 0.05). These data indicate that compared with cross-segment pedicle screw fixation, vertebral pedicle screw short-segment fixation for thoracolumbar vertebral fracture and dislocation obtains more ideal outcomes and higher safety. It is more in line with biomechanics at the same time ensuring the fixing strength.

Objective To explore the influence of early perinatal health care for the pregnancy outcome of gestational diabetes mellitus (GDM).Methods 86 cases of GDM patients who received obstetrical examination and parturition were randomly divided into the two groups by random number table.The control group (n =43) was given traditional health education,and the observation group (n =43) was given early perinatal health care including diet control,proper exercise,mental health and drug therapy.The blood sugar control situation and pregnancy outcome between the two groups were compared and analyzed.Results The fasting blood glucose and 2 hour post-meal blood sugar in the observation group were (5.07 ± 0.73) ％,(4.47 ± 0.29) mmol/L,(6.84 ± 1.31) mmol/L,(1.11 ±0.32) mg/L,which were significant lower than those of the control group [(5.07 ± 0.73) ％,(5.31 ± 0.64) mmol/L,(8.45 ± 1.37) mmol/L,(1.76 ± 0.44) mg/L] (t =5.38,6.91,7.81,3.45,all P ＜ 0.05).The incidence of preeclampsia,cesarean section,postpartum hemorrhage in the observation group were 5.0％,20.0％,7.5％,significant lower than those of the control group(22.5％,57.5％,30.0％) (x2 =5.16,11.85,6.65,all P ＜ 0.05).Compared with the control group,the complication of premature delivery,fetal macrosomia,neonatal hypoglycemia for perinatal infant in the observation group were significantly reduced (x2 =3.91,4.50,4.02,all P ＜ 0.05).Conclusion GDM is correlated with pregnancy outcome,strengthening early perinatal care can effectively reduce the mother infant complications and improve the perinatal prognosis.

In recent years,nutritional support therapy has been increasingly paid attention to scientific and reasonable using for patients.Based on the recent researches,the hot topics on the nutritional risk screening,nutritional status assessment and preoperative and postoperative nutritional support therapy were analyzed,and the strategies and progresses of nutritional support therapy for the postoperative critically ill patients,obese patients and short bowel syndromes or bowel failure patients were summarized,meanwhile,hot issues on the standardized nutritional support therapy in the perioperative period were explored in this article.

[Objective] To explore the levels of folic acid(FA), vitamin(Vit) Bl2 and homocysteine(Hcy) of gestational diabetes mel itus(GDM) patients and the relation among them. [Method] Select 40 GDM cases from our hospital diagnosed with oral glucose tolerance test(0GTT) and 40 healthy pregnant women in the same period, take circulation enzymic method to test Hcy concentration, and take chemiluminescence to measure FA and VitBl2. [Result] GDM patients’Hcy level is in negative relation with VitBl2 and FA levels. Comparing GDM patients’serum Hcy,VitBl2 and FA with normal pregnant group,Hcy level is raised much(P<0.01), FA and VitBl2 are reduced markedly(P<0.01). In later period of GDM pregnancy, they have high Hcy, lack of FA and Vit-Bl2; the pregnancy hypertension shal strengthen the intake of VitBl2 and FA, as wel as have periodical supervision, to reduce Hcy level and decrease the side effects on fetus and injury to pregnant women’s great vessels and micro-vessels.