0.05). But the Wuling Sang could obviously decrease serum TG content than Simvastatin(P0.05). The adverse drug reactions were stomach discomfort(4 patiens in SWS) group, 5.71%), abdominal discomfort(2 patiens in Simvastatin group, 4.55% ) and sleeplessness(5 patiens in Simvastatin group, 11.4%) . CONCLUSION: The results show the TCM drug SWS is effective and softy on treating the patients with primary hyperlipemia.

Carried on the exploration testing of flow rate of infusion device about industry standard YY 0451-2010. Engaged in flow rate experiments adopting different method that are provided by new and old industry standard for samples of the same type. Compared with the result of the dangerous coefficient by calculating the test data, the old standard can be more sensitive to reflect the situation of product flow rate, so it can be applied to conventional control of the products. The method which provided by the new industry standard is suitable for evaluating periodicity the level of product contaminated.
Flowmeters ; Infusion Pumps

The paper introduces the anesthetic journals indexed by SCI-E, moreover a quantitative analysis is performed on the data, instructs anesthetic researchers to submit, search references and subscribe to international anesthetic journals. 22 anesthetic journals have own distinctive characteristics. Anesthetic researchers could choose appropriate journals for submitting based on the quality of their papers and regions.

The key mechanism of hypoxic-ischemic encephalopathy(HIE) is two-times energy exhaustion.Recently, electrophysiology, cell physiology and imageology are performed to figure out some new biomarkers for clinical diagnosis and prognosis. And now, there are different therapies for HIE. For Sub-low temperature therapy,selecting appropriate time of therapy window is more important, and the therapeutic effects of other therapies,hyperbaric oxygenation, neuroprotectants, neural stem cell transplantation etc, need to be validated clinically.

Objective To explore the effect of health education with integrated traditional Chinese and western medicine on patients with cardio-cerebrovascular disease, in order to reach the aim of preven-tion and treatment of cardio-cerebrovascular disease, promotion of early rehabilitation and maintenance of health in them. Methods 80 cases of patients with cardio-cerebrovascular disease were randomized into the control group and the intervention group with 40 cases in each group, Both groups received routine treatment, the intervention group received health education based upon routine treatment. Questionnaires were formulated to investigate change of bad habit and primary disease,return visit and incidence of compli-cation one year after intervention, X2 test was adopted. Results The change rate of bad habit was higher, the change rate of primary disease,rate of return visit and incidence rate of complication were lower in the intervention group compared with those in the control group. Conclusions Health education with inte-grated traditional Chinese and western medicine for patients with cardio-cerebrovascular disease can in-crease their cognition of self- care,life quality and health level which is worthy of wide application in clinic and community.

Objective To investigate the clinical effect of treating avascular necrosis of femoral head with comprehensive therapy dominated by medical ozone. Methods Joint cavity of femoral articulation was performed blockage and injected with fluids for eliminating inflammation and reliving pain. After 5 to 10 minutes interval, if the patients did not show any abnormal reaction, medical Ozone with the concentration of 30%, 8 to 10ml, was injected to the joint cavity. Meanwhile, needle-knife therapy was used to reduce pressure inside the cavity. Traditional Chinese medicine was also used for the treatment. Results of all 183 femoral articulations of 135 cases, the therapeutic result of 38 articulations perfect, occupying 20.8% (38/183), 88 were good, occupying 48.1% (88/183), 31 were normal, occupying 16.9% (31/183) and 26 were bad, occupying 14.2% (26/183).The total effective rate was 85.8% (157/183). Conclusion The treatment of avascular necrosis of femoral head with comprehensive therapy dominated by medical ozone had outstanding therapeutic effects.

Neonatal jaundice is one of the common diseases in preterm neonates. But there are still some problems to be determined,for example,the clinical diagnosis criteria for neonatal jaundice,the prediction,diagnosis and therapies for hyperbilirubinemia,and diagnosis for bilirubin encephalopathy in early-stage and prevention from bilirubin encephalopathy sequelae.

Insulin is one of the most important hormonal regulators of metabolism. Since the diabetes patients increase dramatically, the chemical properties, biological and physiological effects of insulin had been extensively studied. In last decade the development of NMR technique allowed us to determine the solution structures of insulin and its variety mutants in various conditions, so that the knowledge of folding, binding and stability of insulin in solution have been largely increased. The solution structure of insulin monomers is essentially identical to those of insulin monomers within the dimer and hexamer as determined by X-ray diffraction. The studies of insulin mutants at the putative residues for receptor binding explored the possible conformational change and fitting between insulin and its receptor. The systematical studies of disulfide paring coupled insulin folding intermediates revealed that in spite of the conformational variety of the intermediates, one structural feature is always remained: a "native-like B chain super-secondary structure", which consists of B9-B19 helix with adjoining B23-B26 segment folded back against the central segment of B chain, an internal cystine A20-B19 disulfide bridge and a short α-helix at C-terminal of A chain linked. The "super-secondary structure" might be the "folding nucleus" in insulin folding mechanism. Cystine A20-B19 is the most important one among three disulfides to stabilize the nascent polypeptide in early stage of the folding. The NMR structure of C.elegans insulin-like peptide resembles that of human insulin and the peptide interacts with human insulin receptor. Other members of insulin super-family adopt the "insulin fold" mostly. The structural study of insulin-insulin receptor complex, that of C.elegans and other invertebrate insulin-like peptide, insulin fibril study and protein disulfide isomerase (PDI) assistant proinsulin folding study will be new topics in future to get insight into folding, binding, stability, evolution and fibrillation of insulin in detail.

To investigate the cause,pathogenesis,monifestation and treatment of osteoporosis and bonic arthritis.Bonic arthristis was not the osteoposis.Osteoporosis and bonic arthristis may occured simultaneously.In order to treat the conditions correctly,differentiated diagrosis should be noticed clinically.

Neutrophil genatinase-association lipocalin(NGAL)is a kind of lipocalin of binding proteins that seems to be a popular topic studied much recently,which at first was considered as endogenous bacteriostatic agent.It is bound up with the occurrence,development and prognosis of many kidney diseases.Therefore,it can provide new idea and method on clinical diagnosis and treatment by further study on expression and significance of NGAL in kidney diseases.