0.05). But the Wuling Sang could obviously decrease serum TG content than Simvastatin(P0.05). The adverse drug reactions were stomach discomfort(4 patiens in SWS) group, 5.71%), abdominal discomfort(2 patiens in Simvastatin group, 4.55% ) and sleeplessness(5 patiens in Simvastatin group, 11.4%) . CONCLUSION: The results show the TCM drug SWS is effective and softy on treating the patients with primary hyperlipemia.

Gastroenterology ; Humans

Carried on the exploration testing of flow rate of infusion device about industry standard YY 0451-2010. Engaged in flow rate experiments adopting different method that are provided by new and old industry standard for samples of the same type. Compared with the result of the dangerous coefficient by calculating the test data, the old standard can be more sensitive to reflect the situation of product flow rate, so it can be applied to conventional control of the products. The method which provided by the new industry standard is suitable for evaluating periodicity the level of product contaminated.
Flowmeters ; Infusion Pumps

Cardiac Resynchronization Therapy ; China ; Chronic Disease ; Heart Failure ; therapy ; Humans ; Practice Guidelines as Topic

Objective To observe the effect of laser and intubation applied in recurrent nasolacrimal duct-blok.Methods 116 cases of recurrent nasolacrimal duct-blok patients were selected and divided into the observation group and control group by random number table.Only laser was given in the control group,and intubation added in the observation group.All the cases were followed up more than 1 year,and the effects in both group were compared. Results There were 63 effective cases in the observation group,and efficacy rate was 83.33%.And 17 effective cases in the control group,efficacy rate was 41.56%.The efficacy rate in the observation group was higher than that in the control group (χ2 =31.915,P <0.05).There was no false passage in both groups after laser given.Conclusion The effect of laser combined with intubation was better than that of laser alone in recurrent nasolacrimal duct-blok treatment.It was valuable to refractory and recurrent nasolacrimal duct-blok treating.

Objective:To discuss the curative effect of atorvastatin intensive treatment on lipid-lowering in the patients with type 2 diabetes and its influence on vascular endothelial function. Methods: Totally 74 cases of patients with type 2 diabetes were selected and divided into the intensive group ( n=37 cases) and the ordinary group ( n=37 cases) at random. The patients in the two groups were given routine medical treatment, such like diet adjustment, moderate exercise and drug control etc, and the patients in the inten-sive group were additionally given 40 mg atorvastatin orally, once a day, while the patients in the ordinary group were additionally given 20mg atorvastatin orally, once a day for 12 weeks. The changes of blood fat, von willebrand factor (VWF) of serum vascular endothe-lial function, plasma thrombomodulin ( PTM) and vascular endothelial cadherin ( VEC) levels of the patients before the treatment and in the 12th week after the medical treatment were observed and compared, and the adverse drug reactions ( ADR) were evaluated as well. Results:After the 12-week medical treatment, TC, TG and LDL-C levels of the patients in the two groups were obviously de-clined than those before the treatment, while HDL-C levels were obviously raised than those before the treatment ( P<0. 05 or P<0. 01), and the changes in the intensive group was more notable than those in the ordinary group (P<0. 05). Meanwhile, serum VWF, PTM and VEC levels were obviously declined than those before the treatment (P<0. 05 or P<0. 01), and the declining rate in the intensive group was much higher than that in the ordinary group (P<0. 05). Totally 2 and 4 cases of untoward effect appeared re-spectively in the ordinary group and the intensive group with light symptom, and the incidence of ADR showed no statistical difference between the two groups (P>0. 05). Conclusion:Compared with atorvastatin, atorvastatin intensive treatment in the patients with type 2 diabetes has more favorable lipid-lowering effect, which can effectively reduce serum vWF, PTM and VEC levels to improve and rem-edy vascular endothelial function with high security.

Objective To identify the researchers' productivity,the citation states and the grant patterns of the Chinese Journal of Hepatobiliary Surgery through citation analysis.Methods Articles published in the Chinese Journal of Hepatobiliary Surgery between 2009 to 2012 were collected from the Chinese Science Citation Database.These articles were analyzed with statistics and bibliometrics.The indicators included cooperation degree,core authors,distribution of grant,authors' origin and citation states.Results Of the 1321 papers which were published by the journal during the study period,505 papers were cited 923 times.Of the 1111 first authors,957 (86.14％) published one paper only.There were 154 core authors (13.86％ of first authors),and they published 364 papers (27.55％).There were 14 high-productivity institutes,which published 299 papers (22.63％).According to the geographical distribution,Beijing ranked first with 190 (14.38％) papers.The second was Shanghai with 156 (11.81％),the third was Jiangshu province with 134 (10.14％),the fourth was Zhejiang province with 132 (9.99％),and the fifth was Guangdong province with 101 (7.65 ％) papers.1262 papers were completed by collaborate teams of more than one author.The cooperative rate was 95.53％ and the cooperative degree was 4.67.361 papers were funded by 553 supporting foundations.Conclusions The authors of the Chinese Journal of Hepatobiliary Surgery were geographically widely distributed.Some were core authors with high-productivity.They were highly cited and with good cooperation degree.Beijing,Shanghai,Jiangshu,Zhejiang and Guangdong provinces play important roles in research on hepatobiliary surgery.

BACKGROUND:The clinical treatment of thoracolumbar fractures and dislocation of the patients can be treated with pedicle screw fixation through adjacent vertebral segments. With the increased incidence of disease, many problems were found such as fixator loosening and breakage. OBJECTIVE:To compare the effectiveness of vertebral pedicle screw fixation versus cross-segment pedicle screw fixation for thoracolumbar vertebral fracture and dislocation. METHODS:100 patients with thoracolumbar vertebral fracture and dislocation were chosen in the 474 Hospital of Chinese PLA from February 2013 to May 2014. The patients were randomly assigned to two groups (n=50). Patients in the control group were treated with cross-segment pedicle screw fixation, and those in the observation group were treated with the vertebral pedicle screw fixation. Parameters of imaging were compared and observed. RESULTS AND CONCLUSION: Significant differences in the spinal canal area improvement value and internal fixation failure rate were detected between the two groups (P < 0.05), and the observation group was better than the control group. The height ratio of anterior border of the vertebral body was higher at 12 months after treatment than that pretreatment, but Cobb angle was lower than pretreatment (P < 0.05). These data indicate that compared with cross-segment pedicle screw fixation, vertebral pedicle screw short-segment fixation for thoracolumbar vertebral fracture and dislocation obtains more ideal outcomes and higher safety. It is more in line with biomechanics at the same time ensuring the fixing strength.

Objective To explore the influence of early perinatal health care for the pregnancy outcome of gestational diabetes mellitus (GDM).Methods 86 cases of GDM patients who received obstetrical examination and parturition were randomly divided into the two groups by random number table.The control group (n =43) was given traditional health education,and the observation group (n =43) was given early perinatal health care including diet control,proper exercise,mental health and drug therapy.The blood sugar control situation and pregnancy outcome between the two groups were compared and analyzed.Results The fasting blood glucose and 2 hour post-meal blood sugar in the observation group were (5.07 ± 0.73) ％,(4.47 ± 0.29) mmol/L,(6.84 ± 1.31) mmol/L,(1.11 ±0.32) mg/L,which were significant lower than those of the control group [(5.07 ± 0.73) ％,(5.31 ± 0.64) mmol/L,(8.45 ± 1.37) mmol/L,(1.76 ± 0.44) mg/L] (t =5.38,6.91,7.81,3.45,all P ＜ 0.05).The incidence of preeclampsia,cesarean section,postpartum hemorrhage in the observation group were 5.0％,20.0％,7.5％,significant lower than those of the control group(22.5％,57.5％,30.0％) (x2 =5.16,11.85,6.65,all P ＜ 0.05).Compared with the control group,the complication of premature delivery,fetal macrosomia,neonatal hypoglycemia for perinatal infant in the observation group were significantly reduced (x2 =3.91,4.50,4.02,all P ＜ 0.05).Conclusion GDM is correlated with pregnancy outcome,strengthening early perinatal care can effectively reduce the mother infant complications and improve the perinatal prognosis.

Objective To understand the detection situation of Mycoplasma pneumoniae (MP)and Chtamydia trachomatis (CT) in children with respiratory tract infection.Methods MP and CT were simultaneously measured by fluorogenic quantitative PCR in 1393 children patients with respiratory tract infection.Results The total detection rates of MP and CT were 30.4%,in which MP was 21 .8%,CT was 9.3% and MP complicating CT was 0.65%.In the season distribution,the detection rates of MP and CT were highest in summer.In the age distribution,the detection rate of MP in the over 3-year-old group was higher than that in the other age groups,the differences had statistical significance(P <0.05).The detection rate of CT in the less than 1-month-old group was higher than that in other age groups with statistical difference(P <0.05).Conclusion MP and CT are easy to be detected out in summer;MP is easy to be detected out in children over 3 years old than other age groups;MP is easy to be detected out in neonates than other age groups.Fluorogenic quantitative PCR is rapid,sensitive and highly specific for the diagnosis of MP and CT infec-tions.