ObjectiveTo investigate different personality traits and psychological interventions'effect on the patients' anxiety in fiberbronchoscope examination.MethodsThe eysenck personality questionnaire(EPQ)scale and Zung self-rating anxiety scale(SAS) were used to assess the patients.The patients were randomly divided into experimental and control groups,the experimental group,respectively,the implementation of cognitive therapy and relaxation treatment of psychological intervention,psychological evaluation was investigated again before fiber bronchoscopy.ResultsThe scale showed that it had significant difference(P＜0.05 ) between before and after the psychological intervention( before intervention:55.8 ± 1.50,54.9 ± 1.62,57.84 ± 2.13 ; after intervention:46.2 ± 1.38,45.3 ± 1.47,59.26 ± 2.41 ).The patients'personality trait was correlated with their anxiety(P＜0.01 ).ConclusionsThe psychological intervention can be effective in reducing patients'anxiety,and it can help patients take the initiative to meet the inspection,improve the success rate of inspection.And different personality traits can effect on patients' anxiety level.

In this study,we presented data that K562,YAC-1 and LAC-1 cells or tumor-membrane-associated protein could stimulate BCG-treated macrophages from BALB/c mice to produce cy-totoxic factor (M?-CF). CF-inducing activity of K562 membrane or tumor cells remainde afterheat-treated at 100℃ for 20 min, but decreased by trypsin digestion or NaIO_4 oxidixa-tion. Thisactivity was also hibited by ConA or D-Man, but not by Gal. and Giu. The results suggested thatgiycoprotein containing D-Man on tumor cell surface was responsible for traggering M?s toproduce CF.

Objective To assess the efficacy of nebulized budesonide and salbutamol in the treatment of asthma by Meta‐analy‐sis .Methods According to the requirements of Cochrane systematic review ,a through literature search was performed among Wan‐fang database ,CNKI database ,VIP database of Chinese Periodicals and Pubmed database .Meta‐analysis was conducted on a total of 4 649 patients involved in 51 papers that met the inclusion criteria by RevMan4 .3 software .Results Compared with control group (RR=1 .27 ,95% CI=1 .23-1 .32) ,budesonide group which was treated by atomization inhales of nebulized budesonide based on routine treatment(RR=1 .31 ,95% CI=1 .16-1 .49) and salbutamol group which was treated by atomization inhales of salbutamol based on routine treatment(RR=1 .23 ,95% CI= 1 .17 -1 .28) ,the combined group which was treated by atomization inhales of nebulized budesonide and salbutamol based on routine treatment exhibited higher rates of total effectiveness with significant inter‐group difference when taking rates of total effectiveness as index(P<0 .01) .When taking hospitalization rate as index ,the result of the combined group was lower ,compared with the salbutamol group (RR=0 .34 ,95% CI=0 .13-0 .90) ,and the intergroup differ‐ence was significant(P<0 .05) .Conclusion The effect of nebulized budesonide and salbutamol in the treatment of asthma is cer‐tain .

Objective To explore the effects of collaboration intervention on self-efficacy and self-perceived burden in stroke patients. Methods 92 stroke patients hospitalized in the neurology department from January to June, 2014 were divided into control group (n=46) and intervention group (n=46). The control group received routine nursing and the intervention group received collaboration intervention in addi-tion. They were assessed with Self-Efficacy for Managing Chronic Diseases and Self-perceived Burden Scale before and after intervention. Results There was no difference in the scores of self-efficacy and self-perceived burden between groups before intervention (t<0.585, P>0.05). The score of self-efficacy was more in the intervention group than in the control group (t=3.483, P<0.001) after intervention, and was less of self-perceived burden (t=-5.698, P<0.001). Conclusion The collaboration intervention can improve self-efficacy and relieve self-per-ceived burden in stroke patients.

Objective To evaluate the cause and treatment of complication of percutaneous intra-arterial femoral port-catherter system(PCS) implatation. Methods Two hundreds and two patients with malignant tumors in the thorax, abdomen, pelvis and limbs were treated by using chemotherapy and lipiodol embolization via PCS. The related complications rate was 17.3%(35/202). Results The complication included incision infection delayed healing, and wound dehiscence 17.1%(6/35); local hemorrhage 5.7%(2/35); falling down and detachment of catheter of PCS 5.71%(2/35) and 2.86%(1/35) respectively loosening 2.86%(1/35) and changing direction 2.86%(1/35). The indwelling catheter blockage was 31.4%(11/35) and migrating of catheter tip was 28.6%(10/35). Most of these cases were recovered after appropriate management without any fatal and serious outcomes. Conclusions The Technique of percutaneous intra-arterial femoral port-catheter system implantation is safe and reliable. The related complication is slight and easy for management.

OBJECTIVE:To develop a capillary electrophoresis method for determing the enantiomer of ceftriaxone Na.METHODS:A chiral resolving agent,?-cyclodextrin,was employed as chiral additive for ceftriaxone Na enantiomeric separation by capillary electrophoresis.In different electrophoresis polarity mode,the effect of pH of background electrolyte and the concentration of ?-cyclodextrin were investigated.RESULTS:The optimal conditions for enantiomeric separation were as follows:separation voltage:28kV,buffer solution:NaH2 PO4 50mmol/L,?-CD 0.04mmol/L,Tirs 3.0mmol/L,pH7.15.CONC_LUSION:The method is simple,sensitive,rapid and accurate,and can be used for the quality control of ceftriaxone Na enantiomers.There was significant difference in contents of enantiomers of ceftriaxone Na between products of two factories.We suggest that a quality control method for ceftriaxone Na enantiomer should be established,which will provide scientific basis for quality control of drug and clinical choice of effective antibioties.

Fat Emulsions, Intravenous ; administration & dosage ; chemistry ; metabolism ; Humans ; Lipid Peroxidation ; Nutritional Support ; methods

Objective To study the surgical treatment of left colon cancer complicated with acute abdo-men.Methods From January 2000 to Dcember 2008,the clinic data of 36 patients with left colon cancer complicated by acute abdomen were analyzed retrospectively.All cases have been chosen emergency opera-tion.One-stage colectomy and annstomosis were performed in 28 cases,Hartmann in 5 cases and palliative colostomy in 3 cases.Results Anastomic leakage was found in one case after operation,infection of inci-sion happended in 4 cases,infection of lung happened in 2 cases,the times of defecation rised in one case,one patient died.Conclusion More attention shoud be paid to left colon cancer complicated by acute abdo-men.According to the patients'status,different operative manners were chosen.One-stage operation should be chosen firstly to improve quality of life and avoid staged operation.

BACKGROUND: The small change of the membrane potential (Em) of vascular smooth muscle cells (VSMC) could result in significant alteration in tension, and the membrane depolarization was closely associated with the development of hypertension.OBJECTIVE: To study the resting Em of VSMC from the middle cerebral artery (MCA) of stroke-prone spontaneously hypertensive rats (SHRSP) and the reactivity of Em to KCl and norepinephrine (NE).DESIGN: An animal experiment of comparative analysis.SETTING: Institute of Materia Medica, Shandong Academy of Medical Sciences.MATERIALS: Eighteen male SHRSP and 26 male Wistar rats were used.METHODS: ① Rats in both groups were anesthetized with intraperitoneal injection of ethyl carbamate (1 g/kg), the brains were removed quickly, and the Em of VSMC was recorded by intracellular microelectrodes. ② The effects of different concentrations of KC1 (10, 20, 50 mmol/L) and NE (10-7,10-6, 10-5 mol/L) on the Em of VSMC were observed.MAIN OUTCOME MEASURES: ① Em of VSMC in both groups; ②Effects of different concentrations of KC1 and NE on the Em of VSMC.RESULTS: ① The Em was obviously lower in SHRSP than in the Wistar rats [(-48.2±3.1), (-64.4±4.3) mV]. ② Both KC1 (10, 20, 50 mmol/L)and NE (10-7, 10-6, 10-5 mol/L) could cause the depolarization of Em of MCA in a concentration-dependent manner. The reactivity to MCA of SHRSP was obviously increased as compared with the Wistar rats.CONCLUSION: The resting Em of VSMC from the MCA of SHRSP was lower, and the reactivity of VSMC to KCl and NE was significantly stronger than that of Wistar rats.

Objective To evaluate the clinical diagnostic value of coronary artery calcification score(CACS)of multi-slice spiral computed tomography(MSCT)combined with carotid intima-media thickness(IMT)measure in elderly patients with coronary artery disease(CAD). Methods　CACS of MSCT,carotid IMT measure,and coronary angiography were performed in 68 patients,including 36 cases with CAD(CAD group)diagnosed by coronary angiography and 32 cases(control group)with coronary arterial stenosis(＜50% stenosis).CACS and carotid IMT were compared between two groups. Results　The coronary artery calcification score was significantly increased in CAD group compared with the control group[(349.5±86.3)vs.(74.7±25.2),t=13.670,P＜0.01],and it was increased with the severity of coronary arterial stenosis.The carotid intima-media thickness in CAD group showed significant difference with that in control group[(1.11±0.05)mm vs(0.69±0.13)mm,t=13.587,P＜0.01].In CAD group,CACS exhibited a significant positive correlation with carotid IMT(r=0.950,P＜0.01).The positive rates of CACS and carotid IMT were both 77.8% (28 cases)in CAD group and both 12.5%(4 cases)in control group,which showed significant difference between two groups(X2=28.976,P＜0.01). Conclusions　CACS of MSCT combined with carotid IMT have high sensitivity and specificity in evaluating coronary arteriaI stenosis.It can be used as a non-invasive examination to diagnose CAD in the elderly.