Cone-beam computed tomography (CBCT) has an important function in understanding implant operations. CBCT can be used to evaluate the basic condition of implant site before implant operation and decide whether it is suitable for implanting. CBCT also ensures whether the direction of implant and the operation method are satisfactory. CBCT can be used pre- or post-operation as long as the case involves the maxillary sinus. Clinical implant cases using CBCT were introduced to evaluate the maxillary sinus pre- or post-operation.
Cone-Beam Computed Tomography ; Humans ; Maxillary Sinus ; Postoperative Period

Protein degradation mediated by ubiquitin-proteasome pathway is involved in many biological processes.SCF complex is a sort of important E3 ubiquitin-ligase enzyme.Fbx4 protein is one of F-box protein family members,an important component of substrate-specific ScF Fbx4/αβ-crystallin ligase,and a subunit of SCF complex.Inactivation of Fbx4 protein or alteration of its expression level will influence activity of SCF Fbx4/αβ-crystallin ligase,thus will influence expression level of Cyclin D1.And Fbx4 protein is also an important regulatory factor for telomere maintenance.

Spontaneous internal carotid artery dissection is a group of (c)linical uncommondiseases,but it is a potentially catastrophic non-traumatic acute critical illness.The improvement of knowledge and understanding of the disease by clinicians will help to take preventive measures and improve the levels of diagnosis and treatment.This article reviews the advances in clinical features,diagnosis and treatment of spontaneous internal carotid artery dissection.

Objective To understand the prevalence of internet addiction disorder(IAD)and explore its relationship with suicidal tendency of undergraduates.Methods A total of 1517 undergraduates were investigated by using Internet Addiction Scale(IAS),Beck Hopelessness Scale(BHS)and self-made questionnaire.Results The prevalence of lAD was 14.8％.Males,single child,and those at the second grade,with poor performance or higher family income were at a higher risk of internet addiction(P ＜ 0.01).There was significantly positive correlation between internet addiction and suicidal tendency in undergraduates(x2 =76.30,P ＜ 0.01,r =0.40).The risk of suicidal tendency was significantly increased in the high internet addiction score group(OR =12.29,95 ％ CI 6.33 to 23.84).Conclusion Higher prevalence of IAD was found in the undergraduates,which could contribute to the increasing suicide.

Bronchial asthma is a chronic inflammation airway disease.The imbalance of T helper cell (Th) 1/Th2 immunity plays an important role in the pathogenesis of allergic asthma.Recent years a new T cell lineage has been recognized as Thl7 cells because they can produce cytokines interleukin-17.The new studies find that interleukin-17 is a negative regulator of asthma,and interleukin-17 or Th17 cells may represent an interesting therapeutic target in asthma.

Macrolide antibiotics are broad-spectrum, with activity against a range of Gram-positive, Gram-negative organisms and some anaerobes. The components of macrolide antibiotics are generally complicated. Therefore, it is very important to establish impurity profiles of these antibiotics to ensure their safety and process control. Compared with classical methods, the liquid chromatography-mass spectrometry method is particularly advantageous to characterize minor components at trace levels in terms of sensitivity, efficiency and selectivity, thus more and more widely used in establishments of impurity profiles. In this study, the general approaches to characterize minor components in complex pharmaceutical matrix, fragmentation pathways of 14- and 16-membered macrolide antibiotics and the establishment of the impurity profile of acetylspiramycin were given to provide valuable enlightenments to establish the impurity profiles of pharmaceutical products.

Objective To investigate the efficacy and toxicity of thalidomide plus irinotecan and cisplatin treatment for recurrent small cell lung cancer.Methods 62 Patients with recurrent small cell lung cancer in the same period were randomly divided into observation group and control group according to the principle of minimum distribution imbalance index.The observation group patients were treated with thalidomide plus irinotecan and cisplatin chemotherapy,and the control group patients were treated with irinotecan and cisplatin chemotherapy.The efficacy and toxicity of the two groups were compared.Results The overall response rate in the group observation was 86.7％ compared with 63.3％ in the control group,and the difference had statistical significance (x2 =8.52,P ＜ 0.05).The major toxicities were hematologic toxicity and gastrointestinal symptoms,and the side effects differences were not statistically significant (x2 =0.18,P ＞ 0.05).Conclusion The treatment of recurrent small cell lung cancer with irinotecan and cisplatin in combination with thalidomide has high efficiency,and the toxicity can be tolerated.