1.Radiographic evaluation of cone-beam computed tomography for oral implants: maxillary sinus.
West China Journal of Stomatology 2015;33(4):331-335
Cone-beam computed tomography (CBCT) has an important function in understanding implant operations. CBCT can be used to evaluate the basic condition of implant site before implant operation and decide whether it is suitable for implanting. CBCT also ensures whether the direction of implant and the operation method are satisfactory. CBCT can be used pre- or post-operation as long as the case involves the maxillary sinus. Clinical implant cases using CBCT were introduced to evaluate the maxillary sinus pre- or post-operation.
Cone-Beam Computed Tomography
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Humans
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Maxillary Sinus
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Postoperative Period
3.Research on Fbx4 protein
International Journal of Surgery 2008;35(12):820-823
Protein degradation mediated by ubiquitin-proteasome pathway is involved in many biological processes.SCF complex is a sort of important E3 ubiquitin-ligase enzyme.Fbx4 protein is one of F-box protein family members,an important component of substrate-specific ScF Fbx4/αβ-crystallin ligase,and a subunit of SCF complex.Inactivation of Fbx4 protein or alteration of its expression level will influence activity of SCF Fbx4/αβ-crystallin ligase,thus will influence expression level of Cyclin D1.And Fbx4 protein is also an important regulatory factor for telomere maintenance.
4.Spontaneous internal carotid artery dissection
International Journal of Cerebrovascular Diseases 2011;19(12):907-910
Spontaneous internal carotid artery dissection is a group of (c)linical uncommondiseases,but it is a potentially catastrophic non-traumatic acute critical illness.The improvement of knowledge and understanding of the disease by clinicians will help to take preventive measures and improve the levels of diagnosis and treatment.This article reviews the advances in clinical features,diagnosis and treatment of spontaneous internal carotid artery dissection.
5.Relationship between internet addiction and suicidal tendency in undergraduates
Chinese Journal of Health Management 2011;05(6):384-386
Objective To understand the prevalence of internet addiction disorder(IAD)and explore its relationship with suicidal tendency of undergraduates.Methods A total of 1517 undergraduates were investigated by using Internet Addiction Scale(IAS),Beck Hopelessness Scale(BHS)and self-made questionnaire.Results The prevalence of lAD was 14.8%.Males,single child,and those at the second grade,with poor performance or higher family income were at a higher risk of internet addiction(P < 0.01).There was significantly positive correlation between internet addiction and suicidal tendency in undergraduates(x2 =76.30,P < 0.01,r =0.40).The risk of suicidal tendency was significantly increased in the high internet addiction score group(OR =12.29,95 % CI 6.33 to 23.84).Conclusion Higher prevalence of IAD was found in the undergraduates,which could contribute to the increasing suicide.
6.Progress of asthma and Th17 cells
International Journal of Pediatrics 2011;38(6):579-582
Bronchial asthma is a chronic inflammation airway disease.The imbalance of T helper cell (Th) 1/Th2 immunity plays an important role in the pathogenesis of allergic asthma.Recent years a new T cell lineage has been recognized as Thl7 cells because they can produce cytokines interleukin-17.The new studies find that interleukin-17 is a negative regulator of asthma,and interleukin-17 or Th17 cells may represent an interesting therapeutic target in asthma.
7.JNK signal transduction pathway in anti-apoptotic effect of NGF on PC12 cells treated with 6-hydroxydopamine
Chinese Journal of Pathophysiology 2010;26(2):277-281
AIM: To investigate the anti-apoptotic effect of nerve growth factor (NGF) on PC12 cells and to observe the mechanism of signal transduction of JNK pathway. METHODS: PC12 cells were treated with 6-hydroxydopamine (6-OHDA) to induce cell apoptosis. NGF and SP600125, the c-Jun N-terminal kinase inhibitors, were added respectively in order to study the relationship between the activity of c-Jun N-terminal kinase and apoptosis of PC12 cells. The cells were divided into control group, 6- OHDA group, NGF group, 6-OHDA plus NGF group, NGF plus SP600125 group. The apoptotic rates of PC12 cells with different treatments were detected by flow cytometry and activities of JNK in PC12 cells were determined by Western blotting. RESULTS: 6-OHDA increased the apoptotic rate and activity of JNK1 in PC12 cells. Incubation with SP600125 or NGF for 15 min before adding 6-OHDA decreased the apoptotic rate of PC12 cells and activity of JNK1 in PC12 cells.CONCLUSION: Activity of JNK is involved in the pro-apoptotic effect of 6-OHDA on PC12 cells. Anti-apoptotic effect of NGF on PC12 cells affected by 6-OHDA is related to the decrease in the activity of JNK1.
8.Material features, biocompatibility of coronary artery stent and related complications following implantation
Chinese Journal of Tissue Engineering Research 2010;14(16):2999-3002
OBJECTIVE:To explore the material features and biocompatibility of coronary artery stent and related complications following implantation.METHODS:The databases of CNKI and Medline were searched by the first author using key words of "coronary artery stent,material,biocompatibility and complications" both in English and Chinese.Meta analysis or repetitive studies were excluded,and 16 papers were included in this analysis.RESULTS:Stent materials play an important role in reducing inflammatory reaction and restenosis following stent implantation.As a medical material for humans,the features of stent should be meet the requirements of reliable distensibility,mechanical persistence,good flexibilit and geometrical stability,possible small diameter,excellent blood compatibility,as well as good corrosion resistance.All of these depended on the mechanical and physical features of materials.CONCLUSION:The study of drug-coating stent and drug-eluting stent reduced the restenosis rates following implantation,and the biodegradable stent also attracted more attention.When treating coronary heart disease with cardiovascular stent,the complications should be avoided except consideration of the successful rate of reperfusion.
9.Effect of Ji Desheng Sheyao on coagulation, liver,kidney function in bee sting injury patients with severe toxic effect
Chinese Journal of Biochemical Pharmaceutics 2015;(12):105-107
Objective To analysis the the effect of Ji Desheng Sheyao on coagulation,liver, kidney function in bee sting injury patients with severe toxic effect.Methods 42 bee sting injury patients with severe toxic effect were collected.Corresponding treatment and nursing measures were given respectively, after the treatment, the coagulation function,liver, kidney function and nursing effect were detected in all patients.Results After treatment compared with control group,there was no significant difference in the coagulation function of the patients in the experimental group;the serum levels of ALT,AST and TBIL were lower in the experimental group (P<0.05); the serum levels of BUN and Scr were lower in the experimental group(P<0.05);the incidence of complications was lower, and the nursing satisfaction was higher in the experimental group(P<0.05).Conclusions Ji Desheng Sheyao and good nursing measures can significantly reduce oxidative stress in patients with severe toxic effect , improve liver and kidney function, reduce the incidence of complications, improve patient care satisfaction.
10.Clinical analysis of ketogenic diet for 25 children with infantile spasms
Chinese Journal of Applied Clinical Pediatrics 2015;30(7):532-534
Objective To assess the efficacy,compliance and safety of ketogenic diet (KD) for children with infantile spasms,thus to provide an effective basis for the treatment of infantile spasms.Methods Twenty-five patients with infantile spasms were treated with KD.The gas chromatography-mass spectrometry and high performance liquid chromatography-mass spectrometry (HPLC-MS/MS) were used,except for metabolic diseases,to detect the blood routine,urine,stool,blood Iipids,liver function,as well as electrocardiogram (ECG),electroencephalograph (EEG),ultrasound of the urinary system and other related checks of all patients.The KD antiepileptic drug therapy was given after all children were admitted to hospital,and KD started directly in all patients without fasting.The efficacy compliance and safety were followed up in this study.Results KD maintenance therapy for 1 month,3 mouths,6 months were given to 25 cases (100%,25/25 cases),to 22 cases (88%,22/25 cases),and to 10 cases (40%,10/25 cases),respectively.Among them 7 patients (28%,7/25 cases) were in complete control of seizures within 1 month.Up to Class Ⅱ,Ⅲ efficacy level accounted for 32% (8/25 cases),12% (3/25 cases),respectively.Thirteen cases of children had varying digestive symptoms,10 cases of them developed asymptomatic hypoglycemia,and 9 cases of children had sleep trouble during KD treatment,but after symptomatic treatment,children's adverse reactions almost subsided.Only 4 cases of children discontinued treatment due to adverse reactions.All children's seizures were fully controlled.Conclusions The effect of KD is sure in the treatment of infantile spasms.Although KD has some adverse reactions,but it can be tolerated;serious body organ dysfunction treated by KD + antiepileptic drugs combination therapy for 1 to 6 months is not found yet,so the therapy is worthy of promotion clinically.