Cone-beam computed tomography (CBCT) has an important function in understanding implant operations. CBCT can be used to evaluate the basic condition of implant site before implant operation and decide whether it is suitable for implanting. CBCT also ensures whether the direction of implant and the operation method are satisfactory. CBCT can be used pre- or post-operation as long as the case involves the maxillary sinus. Clinical implant cases using CBCT were introduced to evaluate the maxillary sinus pre- or post-operation.
Cone-Beam Computed Tomography ; Humans ; Maxillary Sinus ; Postoperative Period

Objective To investigate and compare the therapeutic effect of aripiprazole and risperidone in the treatment of psychiatric symptoms in Alzheimer’s disease dementia. Methods 64 patients of Alzheimer's disease dementia with psychiatric symptoms,were divided into risperidone donepezil group (A) and aripiprazole donepezil group (B ) . Before and 4, 8 weeks after treatment, the BEHAV-AD scale was used to assess the pathological behavior and the side effects scale (TESS) was used to assess adverse drug reactions.Results A group at 4 weeks after treatment BEHAV-AD score showed no significant difference with before treatment ( >0.05), 8 weeks after treatment decreased significantly (<0.05) . Group B 4 weeks and 8 weeks after treatment BEHAV-AD score was significantly decreased ( <0.05) . BEHAV-AD score in Group B 4 weeks and 8 weeks after treatment was significantly lower than group A ( <0.05) .The scores in behavioral disorders, depression, anxiety in Group B were significantly lower than group A ( <0.05), the scores in paranoia ,hallucinations,aggressive behavior, delirium showed no significant difference between two groups ( >0.05) . 4 weeks after treatment,the two groups had no significant difference in TESS score ( >0.05), 8 weeks after treatment the TESS scores in group B were significantly lower in group A ( <0.05) .Conclusion Aripiprazole + donepezil can effectively alleviate the symptoms of these patients with lower mental side effects, and has better effect in treatment of Alzheimer's disease dementia with psychiatric symptoms.

Objective To investigate the efficacy and toxicity of thalidomide plus irinotecan and cisplatin treatment for recurrent small cell lung cancer.Methods 62 Patients with recurrent small cell lung cancer in the same period were randomly divided into observation group and control group according to the principle of minimum distribution imbalance index.The observation group patients were treated with thalidomide plus irinotecan and cisplatin chemotherapy,and the control group patients were treated with irinotecan and cisplatin chemotherapy.The efficacy and toxicity of the two groups were compared.Results The overall response rate in the group observation was 86.7％ compared with 63.3％ in the control group,and the difference had statistical significance (x2 =8.52,P ＜ 0.05).The major toxicities were hematologic toxicity and gastrointestinal symptoms,and the side effects differences were not statistically significant (x2 =0.18,P ＞ 0.05).Conclusion The treatment of recurrent small cell lung cancer with irinotecan and cisplatin in combination with thalidomide has high efficiency,and the toxicity can be tolerated.

Spontaneous internal carotid artery dissection is a group of (c)linical uncommondiseases,but it is a potentially catastrophic non-traumatic acute critical illness.The improvement of knowledge and understanding of the disease by clinicians will help to take preventive measures and improve the levels of diagnosis and treatment.This article reviews the advances in clinical features,diagnosis and treatment of spontaneous internal carotid artery dissection.

Objective To understand the prevalence of internet addiction disorder(IAD)and explore its relationship with suicidal tendency of undergraduates.Methods A total of 1517 undergraduates were investigated by using Internet Addiction Scale(IAS),Beck Hopelessness Scale(BHS)and self-made questionnaire.Results The prevalence of lAD was 14.8％.Males,single child,and those at the second grade,with poor performance or higher family income were at a higher risk of internet addiction(P ＜ 0.01).There was significantly positive correlation between internet addiction and suicidal tendency in undergraduates(x2 =76.30,P ＜ 0.01,r =0.40).The risk of suicidal tendency was significantly increased in the high internet addiction score group(OR =12.29,95 ％ CI 6.33 to 23.84).Conclusion Higher prevalence of IAD was found in the undergraduates,which could contribute to the increasing suicide.

Bronchial asthma is a chronic inflammation airway disease.The imbalance of T helper cell (Th) 1/Th2 immunity plays an important role in the pathogenesis of allergic asthma.Recent years a new T cell lineage has been recognized as Thl7 cells because they can produce cytokines interleukin-17.The new studies find that interleukin-17 is a negative regulator of asthma,and interleukin-17 or Th17 cells may represent an interesting therapeutic target in asthma.

Objective To investigate uncertainty in illness of family members of patients with malignant tumor,to explore the factors that affect uncertainty in illness of family members of patients with malignant tumor,and to provide clinical basis for clinical doctors and nurses implementing effective interventions for their patients.Methods Questionnaires were conduted to investigate uncertainty in illness of family members of patients with malignant tumor and explore the related factors.The measurements included three parts,Chinese version of Mishel uncertainty in illness scale for family member,self-designed questionnaire about family general condition,patients disease information.Results The total score of uncertainty in illness was 82.71±9.93,more than 50 ％ (75 score) of the highest PPUS-FM score.There were statistical significances of uncertainty in illness in education (F =8.06,P ＜ 0.05),family income (F=3.14,P ＜ 0.05),residence place (F =3.99,P ＜ 0.05) and frequency of hospitalization (F =4.85,P ＜ 0.05).Conclusion Family members of patients with malignant tumor have a higher level of uncertainty in illness.Education,family income,residence place and frequency of hospitalization have a certain effect on uncertainty in illness of family members of patients with malignant tumor.

Cirrhotic portal hypertension can lead to changes in the cardiovascular system,including hyperdynamic circulation,increased cardiac output,increased splanchnic blood flow,increased heart rate,peripheral vasodilatation,decreased resistance,and a drop in blood pressure.This hemodynamic disorder not only plays an important role in the maintenance of portal hypertension,but also causes retention of sodium and water,ascites,hepatorenal syndrome,and hepatopulmonary syndrome.Recently,there is an increased interest in clinical research reports that suggest treatments for cirrhotic portal hypertension.Therapies involve internal medicine,interventional treatment,and surgery for preventing and controlling upper gastrointestinal hemorrhage,splenomegaly,hypersplenism,and other symptoms.Various treatments had some positive effects on the hyperdynamic circulatory state of the cardiovascular system.

Macrolide antibiotics are broad-spectrum, with activity against a range of Gram-positive, Gram-negative organisms and some anaerobes. The components of macrolide antibiotics are generally complicated. Therefore, it is very important to establish impurity profiles of these antibiotics to ensure their safety and process control. Compared with classical methods, the liquid chromatography-mass spectrometry method is particularly advantageous to characterize minor components at trace levels in terms of sensitivity, efficiency and selectivity, thus more and more widely used in establishments of impurity profiles. In this study, the general approaches to characterize minor components in complex pharmaceutical matrix, fragmentation pathways of 14- and 16-membered macrolide antibiotics and the establishment of the impurity profile of acetylspiramycin were given to provide valuable enlightenments to establish the impurity profiles of pharmaceutical products.