1.Clinical Thinking Training Based on a Medical Record from Treatise on Febrile Diseases, Synopsis of Golden Chamber and Warm Diseases Theory Comprehensive Practical Training Course
Chinese Journal of Information on Traditional Chinese Medicine 2015;22(8):121-123
Based on a typical medical record from Treatise on Febrile Diseases, Synopsis of Golden Chamber and Warm Diseases Theory Comprehensive Practical Training Course, this article set group discussion as clues, and analyzed the connection and differences of etiology and pathogenesis by combining febrile diseases, golden chamber, and warm diseases. It emphasized the establishment of clinical thinking in medical records and divergent thinking extended from clinical thinking. Through the analysis of the typical medical record, this article hoped to provide references for the comprehensive study and application of febrile diseases, golden chamber, and warm diseases.
2.Observation on the effect of endoscopic sinus low-temperature plasma-assisted sinus surgery combined with antifungal drug in treatment of fungal nasal-sinusitis
Chinese Journal of Primary Medicine and Pharmacy 2013;20(14):2117-2118
Objective To study the clinical effect of surgery combined with antifungal drug in treatment of fungal nose-sinusitis.Methods The clinical data of 108 cases with fungal nose-sinusitis were retrospectively analyzed.All patients were treated with nasal endoscopic sinus surgery.According to whether the patients received antifungal drugs after low-temperature plasma-assisted surgery,the patients were divided into the treatment group and the control group.The treatment group(56 cases) was given antifungal fluconazole after low-temperature plasma-assisted endoscopic sinus surgery.52 cases in the control group were washed by 0.9% sodium chloride solution after conventional endoscopic sinus surgery.The patients were followed up for 6 months to 2 years,the therapeutic effect and recurrence were compared between the two groups.Results 56 patients of the treatment group,49 cases were cured,7 cases improved,no recurrence.52 cases in the control group,47 cases were cured,improved in 4 cases,ineffective in 1 case,3 cases of recurrence.The recurrence rate of the treatment group was significantly lower than the control group (x2 =4.82,P < 0.05).Conclusion The low-temperature plasma-assisted surgery combined with antifungal drug.in the treatment of fungal nose-sinusitis has exact efficacy,and has significant effect on the prevention and reduce the relapse rate,which worthy of clinical promotion.
3.Selection of the treatment strategies of myelodysplastic syndromes based on clone category
Journal of Leukemia & Lymphoma 2011;20(12):759-762
Myelodysplastic syndromes(MDS) are heterogeneous clonal stem cell disorders.There are about 40 %-60 % MDS patients with abnormal karyotype.To analyze the clone category is not only useful for diagnosis and evaluating prognosis,but also helpful for the selection of optimal therapy strategies to improve the treatment efficacy.
4.Treatment focused on myelodysplastic syndromes based on cytogenetic categories
Journal of Leukemia & Lymphoma 2010;19(5):262-264
Myelodysplastic syndromes (MDS) are heterogeneous clonal stem cell disorders characterised not only by peripheral cytopenia and bone marrow hyperplasia but also by karyotype. The course of disease, clinical outcome and response to treatment. Cytogenetic categories is a pattern typing the intrinsical features of MDS. It is suggested here that investigating biological characters and group treatment in MDS based on cytogenetic categories may enhance the therapeutic effect and bring benefit to MDS patients.
5.microRNAs and recurrent hepatocellular carcinoma
Journal of International Oncology 2015;(10):783-785
microRNAs (miRNAs)play important roles in recurrent hepatocellular carcinoma by regula-ting translation of target gene expression.Researches show that the abnormal expressions of miRNAs are closely related to the recurrent hepatocellular carcinoma,and the mechanisms include regulation of tumor angiogenesis and proliferation of tumor cells.miRNAs may be the most potential therapeutic targets for recurrent hepatocellu-lar carcinoma and have special advantages in prediction.
6.Research Progress on Clinical Application and Pharmacological Mechanism ofAn-Gong Niu-HuangPill in Treatment of Acute Cerebrovascular Diseases
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(7):1510-1513
An-Gong Niu-Huang (AGNH) Pill is an emergency medication in traditional Chinese medicine (TCM). It has been widely used in the treatment of cerebrovascular diseases, meningitis, toxic encephalopathy, hematosepsis, and various types of fever and coma. Pharmacological studies on AGNH Pill revealed that it had the effects of anti-inflammation, cerebral circulation improvement, brain cell protection, brain injury-reducing, and post-injury brain edema improvement. All these effects became the research hotspots in its therapeutic mechanism study. This article summarized the Chinese medicine and modern medicine understanding of AGNH Pill, its clinical application and pharmacological mechanism in the treatment of acute cerebrovascular diseases in recent years, in order to provide references for clinical practice as well as new thinking and prospect for further research.
7.Therapeutic effect of modified S-P approach without disconnecting the rectus femoris in patients with Pipkin typeⅠandⅡfractures
Chinese Journal of Postgraduates of Medicine 2017;40(9):803-806
Objective To investigate the therapeutic effect of modified S-P approach without disconnecting the rectus femoris in patients with Pipkin typeⅠandⅡfractures. Methods The clinical data of 58 patients with Pipkin type Ⅰ and Ⅱfractures were retrospectively analyzed. Among the patients, 29 patients were treated with conventional S-P approach (conventional group), and 29 patients were treated with modified S-P approach (modified group). The incision length, operation time, bleeding, visual analogue score (VAS), postoperative complications and hip joint function at the final follow-up were compared between 2 groups. Results The patients of 2 groups had not incision infection, and showed primary. X-ray of 3 months after surgery showed fracture healing. There was no statistical difference in the time of follow-up between conventional group and modified group:(16.1 ± 5.2) months vs. (15.8 ± 5.6) months, P>0.05. The incision length, bleeding, VAS 3 d and 4 weeks after surgery in modified group were significantly lower than that in conventional group:(8.1 ± 0.8) cm vs. (12.3 ± 1.2) cm, (144.3 ± 16.5) ml vs. (172.4 ± 21.6) ml, (4.5 ± 1.1) scores vs. (5.9 ± 1.5) scores and (1.6 ± 0.7) scores vs. (2.4 ± 0.8) scores, and there were statistical differences (P<0.05). There were no statistical differences in operation time, VAS 3 months after surgery, incidence of postoperative complications and excellent and good rate of hip joint function at the final follow-up between 2 groups (P>0.05). Conclusions The modified S-P approach without disconnecting the rectus femoris is a better method in patients with Pipkin type ⅠandⅡ fractures, and it has the advantages of revealing more clearly, minimal invasion, lower bleeding and slight postoperative pain.
8.Comparison between laparoscopic cholecystectomy and open cholecystectomy for elderly patients with ;acute cholecystitis
The Journal of Practical Medicine 2015;(6):931-932,933
Objective To compare the effects of different surgical methods for the recovery of elderly patients with acute cholecystitis and provide reference for its clinical treatment. Methods 60 Patients aged 65 years or older undergoing laparoscopic cholecystectomy for acute cholecystitis between January 2010 and December 2013 were selected from the database. The comparison group comprised 76 patients from the same age-group who underwent open cholecystectomy for acute cholecystitis. Then the curative effects of two groups were compared and analyzed. Results 76 patients underwent laparoscopic surgery and 60 had open surgery. The demographic data and co-morbidities were compared between the two groups. The postoperative hospital stay was significantly shorter for patients undergoing laparoscopy (P < 0.05). The overall complication rate was significantly lower for patients undergoing laparoscopy (P < 0.05). There was no statistical significant difference in the operating time and the bleeding among the operation. Conclusions Laparoscopic cholecystectomy is a safe procedure for acute cholecystitis in elderly patients , resulting in fewer complications and shorter hospital stay than open cholecystectomy. Laparoscopic cholecystectomy is worth in the clinical application.
10.Comparative study on the intraocular pressure measurement with three tonometer
Chinese Journal of Practical Nursing 2015;31(16):1230-1232
Objective To investigate the clinical efficacy of ICARE rebounder tonometer (RBT) by comparing the measurement results of ICARE RBT,applanation tonometer (AT) and non-contact tonometer (NCT).Methods This study included 100 glaucoma suspect cases (100 eyes) with their day and night intraocular pressure (IOP) measurement in Beijing Tongren Hospital from May to November,2014.IOP of each eye was measured by two experienced examiners using RBT,AT and NCT for three times respectively and the mean values were recorded as the final result.Results IOP was measured by RBT,AT,NCT,the values were (19.1s5.7),(18.9±5.0),(15.2±5.0) mmHg (1 mmHg=0.133 kPa),respectively.The difference between RBT and AT was (0.2±1.8) mmHg,and the difference between NCT and AT was-(3.8±2.6) mmHg.There was no significant difference in the values between RBT and AT,t=-1.136,P>0.05.There was significant difference in the values between NCT and AT,t=14.714,P<0.01.The results measured by RBT,NCT and AT had correlation,r=0.948,0.822;P<0.01.The relevant value was 0.973 in two examiners with RBT,which consisted with the result with AT.Conclusion RBT meets the clinical needs and can be widely used in clinical work.