Objective To study the clinical effect of surgery combined with antifungal drug in treatment of fungal nose-sinusitis.Methods The clinical data of 108 cases with fungal nose-sinusitis were retrospectively analyzed.All patients were treated with nasal endoscopic sinus surgery.According to whether the patients received antifungal drugs after low-temperature plasma-assisted surgery,the patients were divided into the treatment group and the control group.The treatment group(56 cases) was given antifungal fluconazole after low-temperature plasma-assisted endoscopic sinus surgery.52 cases in the control group were washed by 0.9％ sodium chloride solution after conventional endoscopic sinus surgery.The patients were followed up for 6 months to 2 years,the therapeutic effect and recurrence were compared between the two groups.Results 56 patients of the treatment group,49 cases were cured,7 cases improved,no recurrence.52 cases in the control group,47 cases were cured,improved in 4 cases,ineffective in 1 case,3 cases of recurrence.The recurrence rate of the treatment group was significantly lower than the control group (x2 =4.82,P ＜ 0.05).Conclusion The low-temperature plasma-assisted surgery combined with antifungal drug.in the treatment of fungal nose-sinusitis has exact efficacy,and has significant effect on the prevention and reduce the relapse rate,which worthy of clinical promotion.

Objective Analyze the influence of applying background music on heart rate,blood pressure and dysphoric state of patients during gynecologial examination.Methods A total of 564 patients were randomly divided into music and control group 282 cases each.In control group,the 282 patients were just actualized the routine psychological care.And the other 282 patients of music group were actualized music therapy based on the routine psychological care.After these patients of music group entered examination room,the doctor broadcasted some good background music for them.After 30 minutes,the doctor recorded their heart rate and blood pressure changes and evaluated the anxiety level by using S-AI.Results After the patients of music group had listened to background music for 30 minutes,their systolic pressure and heart rate reduced evidently and the level of anxiety mitigated obviously.Conclusions Applying background music during gynecological examination can relieve anxiety emotion,stabilize heart rate and blood pressure and improve comfort of gynecological examination.It's an effective,simple and convenient nursing care method.

Objective To investigate the therapeutic effect of modified S-P approach without disconnecting the rectus femoris in patients with Pipkin typeⅠandⅡfractures. Methods The clinical data of 58 patients with Pipkin type Ⅰ and Ⅱfractures were retrospectively analyzed. Among the patients, 29 patients were treated with conventional S-P approach (conventional group), and 29 patients were treated with modified S-P approach (modified group). The incision length, operation time, bleeding, visual analogue score (VAS), postoperative complications and hip joint function at the final follow-up were compared between 2 groups. Results The patients of 2 groups had not incision infection, and showed primary. X-ray of 3 months after surgery showed fracture healing. There was no statistical difference in the time of follow-up between conventional group and modified group:(16.1 ± 5.2) months vs. (15.8 ± 5.6) months, P>0.05. The incision length, bleeding, VAS 3 d and 4 weeks after surgery in modified group were significantly lower than that in conventional group:(8.1 ± 0.8) cm vs. (12.3 ± 1.2) cm, (144.3 ± 16.5) ml vs. (172.4 ± 21.6) ml, (4.5 ± 1.1) scores vs. (5.9 ± 1.5) scores and (1.6 ± 0.7) scores vs. (2.4 ± 0.8) scores, and there were statistical differences (P<0.05). There were no statistical differences in operation time, VAS 3 months after surgery, incidence of postoperative complications and excellent and good rate of hip joint function at the final follow-up between 2 groups (P>0.05). Conclusions The modified S-P approach without disconnecting the rectus femoris is a better method in patients with Pipkin type ⅠandⅡ fractures, and it has the advantages of revealing more clearly, minimal invasion, lower bleeding and slight postoperative pain.

Objective To investigate the clinical efficacy of ICARE rebounder tonometer (RBT) by comparing the measurement results of ICARE RBT,applanation tonometer (AT) and non-contact tonometer (NCT).Methods This study included 100 glaucoma suspect cases (100 eyes) with their day and night intraocular pressure (IOP) measurement in Beijing Tongren Hospital from May to November,2014.IOP of each eye was measured by two experienced examiners using RBT,AT and NCT for three times respectively and the mean values were recorded as the final result.Results IOP was measured by RBT,AT,NCT,the values were (19.1s5.7),(18.9±5.0),(15.2±5.0) mmHg (1 mmHg=0.133 kPa),respectively.The difference between RBT and AT was (0.2±1.8) mmHg,and the difference between NCT and AT was-(3.8±2.6) mmHg.There was no significant difference in the values between RBT and AT,t=-1.136,P＞0.05.There was significant difference in the values between NCT and AT,t=14.714,P＜0.01.The results measured by RBT,NCT and AT had correlation,r=0.948,0.822;P＜0.01.The relevant value was 0.973 in two examiners with RBT,which consisted with the result with AT.Conclusion RBT meets the clinical needs and can be widely used in clinical work.

microRNAs (miRNAs)play important roles in recurrent hepatocellular carcinoma by regula-ting translation of target gene expression.Researches show that the abnormal expressions of miRNAs are closely related to the recurrent hepatocellular carcinoma,and the mechanisms include regulation of tumor angiogenesis and proliferation of tumor cells.miRNAs may be the most potential therapeutic targets for recurrent hepatocellu-lar carcinoma and have special advantages in prediction.

Objective To compare the effects of different surgical methods for the recovery of elderly patients with acute cholecystitis and provide reference for its clinical treatment. Methods 60 Patients aged 65 years or older undergoing laparoscopic cholecystectomy for acute cholecystitis between January 2010 and December 2013 were selected from the database. The comparison group comprised 76 patients from the same age-group who underwent open cholecystectomy for acute cholecystitis. Then the curative effects of two groups were compared and analyzed. Results 76 patients underwent laparoscopic surgery and 60 had open surgery. The demographic data and co-morbidities were compared between the two groups. The postoperative hospital stay was significantly shorter for patients undergoing laparoscopy (P < 0.05). The overall complication rate was significantly lower for patients undergoing laparoscopy (P < 0.05). There was no statistical significant difference in the operating time and the bleeding among the operation. Conclusions Laparoscopic cholecystectomy is a safe procedure for acute cholecystitis in elderly patients , resulting in fewer complications and shorter hospital stay than open cholecystectomy. Laparoscopic cholecystectomy is worth in the clinical application.

0.05) . Operation time and bleeding in group A were significantly less than those in group B( P

Objective To analyze the epidemic characteristics of natural foci of plague in Qinghai province in the past twenty years and to provide references for prevention and control of the disease. Methods Excel software was used to analyze the database of human plague cases and the surveillance and survey data of natural foci of plague in Qinghai province from 1999 to 2009. Results Animal plague occurred in Qaidam Basin, Qinghai Plateau and central and southern Plateau year after year, which became key areas of animal plague in Qinghai province. There were many human plague cases every year except 1999, 2000, 2002, 2007, 2008 from 1990 to 2009. Cumulative incidence of human plague was 27 cases, with incidence of 73 cases, 29 cases of death, and death rate 39.73%. Epidemic areas mainly distributed in the 4 states of Yushu, Hainan, Hercynian, Haibei.Prevalent season was from May to October. The most prevalent was pneumonic type among clinical types [60.27%(44/73)]. Conclusions Animal plague has occurred actively in key areas of Qinghai province in recent years,and an outbreak of human plague in some areas is found. Monitoring and early warning should be strengthened in the key areas, and comprehensive prevention and control measures should be implemented to reduce the incidence and prevalence of the plague.

Objective To explore the impact of authentic leadership on silence behavior of nurses and test the mediating effect of organizational support. Methods The 354 valid questionnaires were collected using the a cross-sectional survey with Authentic Leadership Questionnaire, Perceived Organizational Support Scale and Silence Behavior Scale between September to November in 2015, using the multiple line hierarchical regression analysis to test the relationship between variables. Results Authentic leadership could significantly promote the perceived organizational support of subordinate nurses (β= 0.543, P<0.01), which in turn, significantly restrain silence behavior of subordinate nurses (β=-0.323, P<0.01), the perceived organizational support completely mediate the relationship between authentic leadership and silence behavior (β=0.175, P<0.01). Conclusions By constructing the supporting work environment, authentic leadership can eliminates nurses′ voice worry, motivates the voice motivation and efficiency, in turn to break the silence. This article propose the action mechanisms from three perspectives.