0.05).NSAIDs users were older than nonusers by a mean of 11 years, more likely to have a history of UGIG (P=0.002)and cardiac vessel disease(P=0.00 0).NSAIDs users have more number of ulcer or erosion(P=0.001)and fewer hospital stay(P=0.011). Conclusion Proper measures should be employed to decrease NSAIDs induced GI complications.