1.REFRIGERATOR ODOUR FILTER
Chinese Medical Equipment Journal 1989;0(03):-
This refrigerator odour filter,mainly composed of filtering system and extracting system,is a device for positively and swiftly changing various poisonous and odourous air into non-poisonous and odourless one in the refrigerator.It can not only keep all kinds of foods fresh and prevent odour from cross-infiltrating,but also prolong the service life of the refrigerator.
2.Th1/Th2 Cell and Tumor Recurrence
Chinese Journal of Bases and Clinics in General Surgery 2003;0(04):-
Objective To review the relationship between T helper cell 1/T helper cell 2 (Th1/Th2) shift and tumor recurrence. Methods Literatures on Th1/Th2 shift and tumor recurrence were collected and reviewed. Results Th1/Th2 shift can be detected in the host after therapy of the tumor. Tumor cells escape from host immune surveillance by altering Th1/Th2, which could lead to tumor recurrence. Conclusion Th1/Th2 shift is related to tumor recurrence after therapy. Impelling the reverse of Th2 to Th1 and renewing the balance of T helper cells come out to be a new way for tumor therapy.
3.Epigenetics and nasopharyngeal carcinoma
Journal of International Oncology 2014;41(5):335-337
The etiology of nasopharyngeal carcinoma is still not very clear.Epigenetics is proved to play an important role in the occurrence and development of nasopharyngeal carcinoma (NPC).Detection of epigenetics can serve as molecular index of NPC,and it is advantageous to the prognosis and disease of NPC.Different intervention measures in the epigenetics can be used as a new treatment of NPC,as well as the development of new NPC radiotherapy sensitization agent and new drugs.Study of epigenetics changes in nasopharyngeal carcinoma provides a new idea for the diagnosis and treatment in NPC and so on.
4.Antibiotics Clinical Usage in General Hospital
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To investigate the usage of antibiotics for improving the management and proper clinical utilization. METHODS The data of 781 inpatients had been analyzed by field survey in our hospital in July 27,2005.The data were analyzed by computer. RESULTS The rate of antibiotic usage was 56.98%,and the rate of preventive antibiotic usage was 20.74%.Cephalosporins were the first,quinolones were the next and then penicillins in the antibiotics usage.Only 33.57% infectious patients were made bacteria culture and antibiotics drug sensitive test.Most antibiotics were used according to clinical experience. CONCLUSIONS Most of the doctors can use antibiotics properly.The strengthening control and rational antibiotics usage in prevention are the key means to decrease the numbers of irrational application.
5.Clinical Oservation on Transdermal Acupoint Electric Stimulatlion Treat Intractable Hiccups of Blood Diseases Patients
Hongyan HU ; Lina WANG ; Yiping SHEN
Journal of Zhejiang Chinese Medical University 2014;(7):916-917
Objective To observe the clinical effect of the transdermal acupoint stimulation treatment on intractable hiccups of patient with blood disease. [Methods]The 57 inpatients with intractable hiccups induced by chemotherapy or corticosteroids were randomly divided into two groups, percutaneous acupoint electric stimulation group and control group with Ritalin injecting in zusani, from January 2010 to December 2013. Clincal effect and adverse reaction were compared and analyzed after treatment. [Result]There was no significant difference on the clinical effect between two groups,while the adverse reaction in percutaneous acupoint electric stimulation therapy group was relatively mild.[Conclusion] Percutaneous acupoint electric stimulation is an effective method for the treatment of intractable hiccups, which should be popularized in clinical practice.
6.A Case-control Study on Risk Factors for Chronic Gastritis in Yuhang District,Hangzhou
Qifa YANG ; Haiying WANG ; Hongyan SHEN
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(01):-
Objective To explore the risk factors for chronic gastritis in Yuhang district,Hangzhou.Methods All cases came from the population involved in screening for upper gastrointestinal tract diseases in 2002 and were diagnosed by histopathology.The controls were chosen in residents of the same village who had no stomach disease history and dyspeptic symptoms.All subjects were investigated with a questionnaire by interviewers on their lifestyle and health condition.Results The odds ratios of smoking,the family history of chronic gastritis,drinking,sleep quality,oral debris,regular dining,drinking tea and the intake of beans & bean products were 3.012,2.343,1.438,1.384,1.283,0.418,0.603 and 0.809,respectively.Foods taste also took significant effect on chronic gastritis.The odds ratios of sour foods,spicy foods,salty foods and sweet foods were 2.72,2.33,2.22 and 2.06,respectively.Conclusions The risk factors for chronic gastritis were smoking,family history of chronic gastritis,heavy drinking,sleep quality,oral debris,foods flavor.While regularly dining,properly drinking tea and intake of beans and bean products were protective factors.
7.Regulation of saw palmetto extract on immune function in GL261 glioma
Jinglian SHEN ; Hongyan ZHANG ; Yuqin CHE ; Jie ZHU ; Shenjun PENG
Chinese Journal of Immunology 2016;32(9):1299-1302
Objective:To investigate the effect of saw palmetto extract ( SR ) on GL261 glioma in rats and immune system.Methods:The 40 rats were divided into 4 groups randomly,one was the control group without tumor( the blank group) ( n=10) ,the other 30 rats were given subcutaneous inoculation of tumor cells and then divided into 3 groups:the tumor-bearing group( n=10) ,low dose SR group( n=10) ,and high dose SR group( n=10).After 1 week fed,the rats of SR groups were given the saw palmetto extract,low dose group 50 mg/kg once a day every other day and 300 mg/kg of high dose group every other day.The tumor-bearing groups received the same dose of distilled water.After 4 weeks fed, we measured the tumor weight and the inhibition rate was calculated.The tumor cell apoptosis was detected by TUNEL staining.The activity of splenic macrophages was detected by macrophage phagocytosis of chicken erythrocytes and CD4+lymphocytes by flow cytometry.Results:①The SR groups compared with tumor group, the tumor weight was significantly reduced(F=62.678,P=0.000).The tumor inhibition rate was significantly higher in high dose group.②The apoptosis of tumor cells in tumor-bearing group was significantly less than SR groups and the apoptosis was significantly increased after treatment with SR ,especially in high dose SR group(F=1.287,P=0.000).③Compared with the blank group,the macrophage activity decreased remarkablely.SR enhanced the macrophage activity obviously, positively related to doses of SR ( F=141.205,P=0.000;F=126.903,P=0.000).④In the tumor-bearing group,the CD4+lymphocyte count decreased significantly.After SR treatment,the CD4+lymphocyte increased and were positively related to the dose of SR.Conclusion: Saw palmetto extract can strengthen the immune system.
8.Effect of ERK1/2/c-Fos signal pathway on angiotensin-(1-7) inhibiting proliferation of rat glomerular mesangial cell strain induced by angiotensin Ⅱ
Hongyan HE ; Ning SHEN ; Jian LIU ; Xiaoling SHI ; Mingyong WANG
Chinese Journal of Pathophysiology 1986;0(01):-
AIM:To investigate the effect of ERK1/2/c-Fos signal pathway during angiotensin-(1-7)inhibiting proliferation of rat glomerular mesangial cell strain(GMCS)induced by angiotensin Ⅱ.METHODS:Rat glomerular mesangial cells(GMC)were co-cultured with angiotensin Ⅱ and different doses of angiotensin-(1-7).The numbers of GMC were evaluated by crystal violet staining.The amounts of p-ERK1/2 and c-Fos expressions were detected by Western blotting.RESULTS:Angiotensin-(1-7)showed its inhibitory effects on GMC number increasing induced by angiotensin Ⅱ as well as the amounts of p-ERK1/2 and c-Fos expressions in a concentration dependent manner.CONCLUSION:ERK/c-Fos signal pathway is involved in the inhibitory effects of angiotensin-(1-7)on angiotensin Ⅱ-induced GMC proliferation.
9.Application of multi-adaptive filter based on radial basis function neural network for real-time somatosensory evoked potential monitoring
Hongyan CUI ; Xiaobo XIE ; Shengpu XU ; Chongfei SHEN ; Yong HU
International Journal of Biomedical Engineering 2012;35(3):137-141
ObjectiveTo design multi-adaptive filter based on radial basis function (MAF-RBF) for efficiently extracting somatosensory evoked potential (SEP) in real-time SEP monitoring.MethodsWith the optimization of important parameters that influence the performance of radial basis function neural network,the performance of extracting SEP was compared to that of a multi-adaptive filter (MAF),which developed from the combination of well-developed adaptive noise canceller and adaptive signal enhancer.ResultsIn this simulation study,the outputs of MAF-RBF showed a similar waveform with SEP template signals,and a smoother waveform than the.output of MAF.ConclusionWith appropriate parameter values,MAF-RBFNN is able to extract the latency and amplitude of SEP from the extremely noisy background rapidly and reliably without averaging.
10.The effects of Tong Xin-Luo on human umbilical vein endothelial cells impaired by lysophosphatidylcholine
Min YANG ; Jingfang LIU ; Ming SUN ; Huifang SHEN ; Hongyan ZHOU
Journal of Chinese Physician 2012;14(5):607-609
Objective To investigate the effects of Tong Xin-Luo on cultured human umbilical vein endothelial cells (HUVECs) impaired by Lysophosphatidylcholine.Methods The herbage-contained serum of TXL was prepared,HUVECs were cultured in vitro.The study was designated to 4 group:normal control,LPC group,TXL group,and TXL + LPC intervened group.The cell function was determined by cell morphology and MTT colorimetric assay.Results Compaired with normal control group (0.380 ±0.023 ),LPC ( 0.320 ± 0.024 ) could significantly decrease the cells activity,promote cells death ( P <0.05 ).After TXL intervened(0.424 ±0.034),cells activity was significantly increased,cells death was d significantly decreased( P <0.05 ).Conclusions Tong Xin-Luo could protect human umbilical vein endothelial cells function by against the LPC-induced damage.