1.Clinical study of diagnostic difference between preoperative diagnostic curettage and postoperative pathological diagnosis in endometrial carcinoma
Chinese Journal of Postgraduates of Medicine 2014;37(9):42-44
Objective To investigate the diagnostic difference between preoperative diagnostic curettage and postoperative pathological diagnosis in endometrial carcinoma,and provide guidance for the accuracy in preoperative diagnosis of endometrial carcinoma.Methods The data of 124 endometrial carcinoma patients were retrospectively analyzed,including clinical stage,pathological stage,pathological type,histologic grade,etc.Results In 124 endometrial carcinoma patients,102 cases of endometrial carcinoma were found by preoperative diagnostic curettage,the diagnostic accordance rate was 82.3% (102/124),misdiagnosis was in 22 cases,the misdiagnosis rate was 17.7%(22/124).The total accordance rate of preoperative clinical stage and postoperative pathological stage was 81.4% (83/102) in 102 patients who had the same preoperative and postoperative diagnosis,and the accordance rate of Ⅰ stage was 86.1% (62/72),the accordance rate of Ⅱ stage was 72.0%(18/25),the accordance rate of Ⅲ stage was 3/5.The total accordance rate of preoperative diagnostic curettage histologic grade and postoperative pathological histologic grade was 65.7%(67/102),and the accordance rate of G1 grade was 55.6% (25/45),the accordance rate of G2 grade was 69.2% (27/39),the accordance rate of G3 grade was 15/18.Conclusions The pathological type,pathological stage and histologic grade of preoperative diagnostic curettage and postoperative pathological diagnosis in endometrial carcinoma are not always consistent.A variety of diagnostic methods should be considered together in order to reduce the diagnosis difference preoperative and postoperative,and improve the accordance rate of preoperative diagnosis.
2.The visual magnocellular deficit in developmental dyslexia
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(8):763-768
To study the visual magnocellular deficit in alphabetic and Chinese developmental dyslex?ia from behavioral,neural mechanism and intervention studies,critical words in Chinese and English (de?velopmental dyslexia and magnocellular pathway or dorsal stream or contrast sensitivity or coherent mo?tion ) were searched in Chinese and English databases(CNKI,PubMed,ScienceDirect,etc.) from Septem?ber to December,2015. Forty?three relevant articles which aimed to investigate the visual magnocellular defi?cit in developmental dyslexia were selected among 75 articles according to the searching result and the objec?tive of the present study. The results showed that alphabetic studies consistently consistently manifested the magnocellular deficit in developmental dyslexia from the aspects of behavioral performance,neural activities and intervention effects. However,whether the deficit was the cause or the consequence of dyslexia remains controversial. In Chinese,most of studies on magnocellular deficit of developmental dyslexia were behavioral. There were few studies from aspects of neural mechanism and intervention. Alphabetic and Chinese studies consistently manifested magnocellular deficit in developmental dyslexia,suggesting the consistency across lan?guages. However,more comprehensive studies are required to further explore the causal relationship between magnocellular deficit and developmental dyslexia.
3.Rationality Analysis of Prophylactic Application of Antibiotics during Perioperative Period in Patients with Type Ⅱ Incision Operation in Gynecology and Obstetrics before and after Intervention
Yanping HU ; Yuan ZHANG ; Hongyan QIAN
China Pharmacist 2015;(2):258-259,260
Objective:To investigate the rationality of prophylactic antibiotics application during perioperative period in the pa-tients with type Ⅱ incision operation in gynecology and obstetrics in our hospital after the intervention. Methods:Totally 274 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2012 to March 2013 were collect-ed as the control group, another 321 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2013 to March 2014 were collected as the intervention group. The rationality of prophylactic antibiotics application before and after the intervention was compared. Results:Compared with those in the control group, the average administration time, the hos-pitalization time and the cost of antimicrobial agents were significantly decreased in the intervention group (P<0. 05). The incidence of adverse drug reactions and operation incision infection between the two groups was not significant difference (P>0. 05). Compared with those in the control group, the incidence of irrational choice of antibacterial drugs, the combined use without indication, irrational medication time,over-time use, inappropriate use and improper choice of solvents in the intervention group was significantly reduced ( P<0. 05). Conclusion:After the intervention, the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital is improved significantly.
4.Effect of Game Therapy on Childhood Autism:A Case Report
Yingmei MAO ; Qian XIE ; Hongyan LIU
Chinese Journal of Rehabilitation Theory and Practice 2007;13(9):826-828
Objective To investigate the effect of play therapy on childhood autism.Methods A child with autism treated with play therapy was reported.Results and Conclusion The play therapy is helpful to improve the social skill of the children with autism.
5.Stratified analysis on correlation between abnormal blood lipid in senile people and coronary atherosclerotic cardiopathy
Wen YANG ; Yu WANG ; Rong CHU ; Qian ZENG ; Hongyan YANG
Chinese Journal of Tissue Engineering Research 2005;9(19):240-242
BACKGROUND: Hyperlipemia is one of the important risk factors of coronary atherosclerotic cardiopathy. Great attention has been paid on how to explain the correlation between blood lipid and coronary heart disease and the correlation of characteristics and level of blood lipid with coronary heart disease.OBJECTIVE: To probe into the correlation among the characteristics, the level of blood lipid and coronary heart disease in senile people.DESIGN: Case-control observation and stratified analysis.SETTING: Second Cadre Ward of General Hospital of Shenyang Military Area Command of Chinese PLA.PARTICIPANTS: Totally 105 inpatients were selected in coronary heart disease group, diagnosed as coronary heart disease, tallied with WHO Diagnostic Standard on Coronary Heart Diseases, in Second Cadre Ward of General Hospital of Shenyang Military Area Command of Chinese PLA from January 2001 to January 2002. Totally 99 inpatients, by checked, without coronary heart disease and cerebral vascular disorder were selected in the control in the same period.METHODS: 2 mL venous blood was collected in fasting in the morning and the serum was collected after centrifuged at 3 000 r/minute, for 5 minutes. Auto-biochemical analyzer and enzyme kit were used to determine cholesterol, triglycerin, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Compared with the data in the control, the ranges of cholesterol, triglycerin and low density lipoprotein were calculated successively and divided by 10; at the class intervals of 0.53, 0. 39 and 0.29 mmonl/L, the frequency table was worked out. According to the frequency table, P25 (the 25th percentile), P50 (the 50th percentile), P75 (the 75th percentile) and P90 (the 90th percentile) of cholesterol, triglycerin and low density lipoprotein cholesterol were calculated successively. The stratified groups were divided based on P < 25, P25 to PS0, PS0 to P75, P75 to P90 and > P90, by which, the cases belonging to 5 groups were determined in coronary heart disease group and the control respectively. The exposure factor was determined by > P90, compared with other 4 groups, Menta-Haensecel method was used to calculate x2. If the exposure factor was related with coronary heart disease, the relevant coefficient and 95% confidence interval should be calculated. In accordance with the standards (Proposal on Prevention of Abnormal Blood Lipid and Targets of Abnormal Blood lipid on 2-grade Prevention of Coronary Heart Disease), the cases beyond the targets and morbidity were determined in two groups.MAIN OUTCOME MEASURES: Determination of blood lipid, abnormal cases and morbidity in two groups; cases beyond targets of blood lipid and morbidity; stratified comparisons of percentiles in two groups.RESULTS: According to intention measurement, 204 cases entered result and the control, there was no significant difference in cholesterol, triglycerin cases presented hypercholesterolemia, 34.3% cases hypertriglycerlipidemia and 11. 4% cases low density lipoprotein-hypercholesterolemia. It was indicated that the blood lipid was in the normal range among 64. 8% to 88.6% comparison between the cases with cholesterol ≥5.47 mmonl/L and the cases with cholesterol varied from 3.85 to 4.63 mmol/L, the morbidity of coronary heart disease in the former was 2.98 times as high as the latter (x2 = 6.29, 95% confidence interval was 1.27 -6.98) . In the comparison between the cases with cholesterol ≥ 5.47 mmol/L and the cases with cholesterol varied from 4.64 to 5.05 mmol/L, the correlation with coronary Lipid for 2nd Prevention of Coronary Heart Disease, among the patients with coronary heart disease, cholesterol ≥ 4.68 mmonl/L in 54. 2% cases,triglycerin ≥ 1.70 mmol/L in 34. 3% cases and low density lipoprotein ≥ 2.6 mmol/L in 52. 3% cases.CONCLUSION: For senile patients with coronary heart disease, the satisfactory level of cholesterol is 3.85- 4.63 mmol/L. For those with cholesterol ≥ 5.47 mmol/L, compared with those varied from 3.85 to 4.63 mmol/L, the morbidity of coronary heart disease in the former is possibly 2.98 times as same as the latter(x2 = 6.29, 95% confidence interval was 1.27 - 6.98).
6.Role of teaching resource database in blood disease testing technology teaching reform
Hongyan LI ; Zhenjiang HOU ; Qian XU ; Rongqin DAI
Chinese Journal of Medical Education Research 2013;(7):690-692
This paper introduced the necessity, background, principle, content, function of construction of teaching resource database of blood disease testing technology and its role played in teach-ing reform. Construction of teaching resource database made up for the insufficiency of blood disease test-ing technology in teaching time and resource, explored more scientific learning mode and teaching meth-ods and strengthened the cooperation between part-time teachers and professional teachers of blood dis-ease testing technology courses.
7.Investigation and analysis for requirement of hierarchical model of nurses
Ailing FAN ; Hongyan YU ; Qian YOU ; Yanhua ZHAO
Chinese Journal of Practical Nursing 2008;24(15):50-51
Objective To study the influence of hierarchical model on the professional attitude and quality improvement of nurses and supply references for the apphcation of hierarchical model.Methods 310 nurses were divided into the control group(158 cases)and the practice group(152 cgses).The practice group adopted hierarchical model while the control group did not.Investigation was carried out in 15 aspects such as training requirement,choosing of nursing posts and departure intention,etc.Results The nursing teaching pest and nursing management post in the aspect of post requirement between the two groups had no statistical difference(P>0.05),but statistical difference existed in other items(P<0.05).In the aspect of training requirement evident difference existed in two groups(P<0.05).Conclusion Application of hierarchical model proved to be a pivotal method to improve the professional passion and loyalty of nurses.
8.Clinical efficacy of otolith-repositioning maneuver combined with medical treatment on benign paroxysmal positional vertigo in the elderly patients
Qian HAN ; Shuxiang ZHANG ; Hongyan YUAN ; Ping LIU ; Yaping YAN
Chinese Journal of Geriatrics 2015;34(5):543-545
Objective To investigate the value of otolith-repositioning maneuver combined with medical treatment on benign paroxysmal positional vertigo in the elderly patients.Methods 176 elderly people who suffered from benign paroxysmal positional vertigo were randomly divided into observation group and control group (n=88,each).All patients were treated with basal medicine treatment and compulsive position for 21 days,and patients in the observation group were treated with otolith repositioning maneuver added on the basis.The clinical efficacy and adverse reactions were observed and compared between the two groups after treatment.Results The curative rate and effective rate were higher in observation group than in control group at 2,3 weeks after treatment [50.0% (44/88) vs.11.4% (10/88),70.5% (62/88) vs.47.7% (42/88),77.3% (68/88) vs.29.5% (26/88),93.2% (82/88) vs.86.4% (76/88),x2 =37.32,73.32,37.32,53.43,respectively,all P<0.05].Dizziness combined with nausea and vomiting,and walking instability were both found in the two groups,which had no statistical difference (x2 =3.25,P>0.05).Patients in observation group developed arrhythmia and Tumarkin otolith crisis after treatment.The transfer rate of surgery was lower in observation group than in control group (x2 =45.43,P<0.01).Conclusions Otolith-repositioning maneuver combined with medical treatment have good clinical effect and safety on benign paroxysmal positional vertigo in the elderly.
9.Evaluation of the chemiluminescence immunoassay for diagnosis of syphilis in the clinical screening test
Xiaohong ZHANG ; Qian ZHANG ; Xuehong ZHOU ; Hongyan GENG ; Xiangyi LIU
Chinese Journal of Laboratory Medicine 2014;(10):780-783
Objective To evaluate the specificity of Architect chemiluminescence immunoassay ( CLIA) for diagnosis of syphilis in the clinical screening test.Methods 65 774 syphilis specific antibody results in the Beijing Tongren Hospital were retrospectively analyzed.In this study, Architect CLIA for diagnosis of syphilis was used as a screening test for the pre-operative patients from August 2011 to July 2012.All the repeatedly reactive samples were tested by the tolulized red unheated serum test ( TRUST) and Treponema pallidum particle agglutination ( TPPA) assay.Samples with with discordant results were verified by western blot ( WB) Finally, all the results were statistically analyzed by software SPSS 17.0.Results Among 65 774 samples, 940 (1.43%) were found to be repeatedly reactive using the Architect CLIA.Of these sera, 330 ( 35.11%) were reactive and 610 ( 64.89%) were nonreactive by TRUST.Because a TRUST titer of 1:1was not always sufficient to confirm a TPPA reactive result, all the samples with CLIA reactive results were finally performed by TPPA assays.The results showed that 843 ( 89.68%) were positive and 97 (10.32%) were negative.After arbitrated by the WB, out of 97 TPPA negative sera, 18 (18.56%) were positive;7(7.22%) were indeterminate and 72(74.23%) were negative.Conclusions The specificity of Architect CLIA for diagnosis of syphilis was 99.89%.The results showed that confirmation by TPPA on sera with screening test for syphilis by Architect CLIA effectively decreased the false-positive results and could be suitable for a routine supplementary for syphilis.However, if necessary, the WB should be further utilized.
10.Survey of mental health of rural individuals with HIV/AIDS in a county of Henan Province
Guang CHEN ; Hongyan XIONG ; Qian ZHU ; Qingwei CHEN ; Shiqin WEI
Journal of Third Military Medical University 2003;0(11):-
Objective To investigate the psychological condition of the rural residents with HIV/AIDS.Methods Totally 192 subjects with HIV/AIDS residing in countryside of Henan Province(China)were investigated with questionaire and Symptom Check list 90(SCL-90).Results SCL-90 total score,the number of positive items and the score of each factor for the 192 subjects with HIV/AIDS were higher than those of Chinese normal(P