Objective To explore effect of Medicinal carbon on serum calcium, phosphorus and parathyroid hormone on chronic renal failure dialysis patients.Methods 82 case with chronic renal failure dialysis were selected and divided into two groups.41in control group were treated with conventional therapy, 41 in experiment group were with medicinal carbon 0.3 g, 3 times per day.Serum calcium, phosphorus and parathyroid hormone were compared before and after the treatment.Results Compared with control group, serum creatinine, urea nitrogen and uric acid of the experiment group were lower(P<0.05).The total effective rate of clinical symptoms was higher than control group(P<0.05).Serum calcium, serum phosphorus and parathyroid hormone were lower(P<0.05),the incidence of adverse reactions was lower than the control group(P<0.05).Conclusion Medicinal charcoal can decrease levels of serum calcium, serum phosphorus and serum intact parathyroid hormone in chronic renal failure patients, has good clinical curative effect, with less adverse reaction.