1.Effects of Acer truncatum oil on oxidative stress and inflammatory reaction in rats undergoing one-time exhaustive exercise
Chongqing Medicine 2017;46(22):3043-3045
Objective To explore the effects of Acer truncatum oil on oxidative stress and inflammatory reaction in rats after exhaustive exercise to provide a scientific basis for the prevention of sports injury by Acer truncatum oil.Methods Thirty healthy male SD rats were randomly divided into control group (A,normal diet + saline every day),exhaustive group (B,normal diet + saline daily) and exhaustive with Acer truncatum oil group (C,0.21 mL/kg daily Acer truncatum oil gavage),6 weeks later,the rats performed once exhaustive swimming exercise,then the creatine kinase (CK),lactate dehydrogenase (LDH),cytokine interleukin (IL-1β,IL-10) and tumor necrosis factor alpha (TNF-α) in the serum;malondialdehyde (MDA) homogenate reduction glutathione (GSH),superoxide dismutase (SOD),catalase (CAT) and glutathione peroxidase (GSH-Px) in muscle were measured.Results After exhaustive exercise,when compared with the group A,the serum levels of CK,LDH,IL-1,TNF-α and IL-10 were significantly higher than in the group B(P<0.05,P<0.01,P<0.05,P<0.01,P<0.05),IL-10/ TNF-α ratio had no statistically significant difference(P>0.05),the level of MDA in gastrocnemius muscle increased significantly (P<0.05),GSH level and GSH-PX activity decreased significantly (P<0.05,P<0.01),SOD and CAT activity were not statistically significant (P>0.05).when compared with the group B,serum CK,LDH level and IL-1 β,TNF-α were significantly decreased (P<0.05,P<0.01,P<0.01,P<0.05),IL-10 had no statistical significance (P>0.05),a significant increase in IL-10/TNF-α(P<0.05),the level of MDA of gastrocnemius muscle decreased significantly (P<0.05),the level of GSH and SOD,CAT and GSH-PX were significantly increased (P<0,01,P<0.01,P<0.05,P<0.01).Conclusion Acer truncatum oil can significantly reduce oxidative stress and inflammatory reaction caused by the exhaustive exercise,which has a protective effect on skeletal muscle.
2.Clinical Study in Elderly Hypothyroidism with Coronary Heart Disease
Journal of Medical Research 2006;0(06):-
0.05,there were not significant differences in two groups.In the hypothyroidism group,the characteristics had been improved,such as myxedema、feeling of cold,lowing-sweat、alopeda,The function of thyroid and heart rate had been improved。To compare with matched control,there were significant difference P
3.The research about the relationship between emotional labor and personality of health care workers
Qing HU ; Jian SUN ; Hongwei SUN
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(1):75-77
Objective To explore the relationship between the emotional labor and personality of the health care workers. Methods 168 health care workers in 6 hospitals of Shandong province were surveyed to complete the Emotional Labor Scale and the revised NEO personality inventory(NEO-PI-R). Results The first strategy of emotional labor that workers usually used was natural acting (5.17±1.15),the next one was deep act-ing (4.74±0.78) and the last was surface acting(3.88±1.21). The correlation analysis showed that the extro-version had a negative correlation (r=-0.20, P < 0.05) with the surface acting and a positive correlation (r=0. 31, P<0.01) with the deep acting. The agreeableness had a positive correlation (r=0.22, P < 0.05) with the nat-ural acting. The conscientiousness had a positive correlation (r=0.25, P<0.05) with the deep acting. The extro-version had significant negative influence on surface acting and significant positive influence on deep acting. The a-greeableness had positive significant effect on natural acting and the conscientiousness had positive significant effect on deep acting. Conclusion Personality influenced the emotional labor and gender,age,work tenure and ed-ucational had significant effect on emotional labor.
4.Experimental Study of Kidney Aquaporin-2 Expression in Lung-Qi Deficiency Model Rats
Zhe WANG ; Hongwei SUN ; Hao WANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
Objective To observe the effects of kidney aquaporin-2 (AQP2) expression in Lung-Qi deficiency model rats and provide experimental evidence for the traditional Chinese medical theory that the kidney is related with the lung in charge of regulating the water passage. Method Twenty healthy rats were divided into the model group and the control group. The method of immunohistochemistry and Western blot was used to determine the expression of AQP2 in kidney. RT-PCR was applied to analyze the expression of AQP2 mRNA in lung and kidney tissues. Result The expression of AQP2 and AQP2 mRNA in kidney in model group was higher than in the control group. Conclusion The expression of AQP2 in kidney was higher in Lung-Qi deficiency model rats. One of the substance basis of "lung in charge of regulating the water passage" may be related to the change of AQP2 expression in the kidney tissues.
5.Simple bone cysts in teenagers treated by grafting of bioactive glass and autologous bone marrow
Hongwei LIU ; Junying SUN ; Binghua SONG
Orthopedic Journal of China 2006;0(01):-
[Objective]To investigate the therapeutic results of grafting with bioactive glass and autologous bone marrow for simple bone cyst in teenagers. [Method]From April 2005 to October 2007,16 teenagers with simple bone cyst were reported.There were ten males and six females with a mean age of 18.5 years(range 12 to 30 years).Eight cysts were in the proximal humerus,five in the proximal femur,two in the proximal tibial and one in the distal end of radius.Lining of cavity was removed thoroughly with a curet.The cyst cavity was filled with the mixtures of 45s bioactive glass and autogenous red bone marrow.Five cases of pathologic fracture were fixed with steel plate or intramedullary nail.[Result]All 16 cases of cysts were ossified radiolo gically within six months,with an average time to syst healing of 18 week.A follow-up of 6 to 32 months(mean 18 months) showed satisfactory healing without complications.[Conclusion]The combined grafting with bioactive glass and autologous bone marrow appears to be an effective and simple treatment for simple bone cyst in teenagers.
6.Quantitative tissue velocity imaging in assessing regional myocardial function in acute myocardial infarction treated by coronary stenting.
Shan JING ; Hongwei SUN ; Yonglin HUANG
Chinese Journal of Practical Internal Medicine 2002;0(08):-
Objective The function of regional myocardium of patients with myocardial infarction(MI) treated by intra-coronary stenting was determined with quantitative tissue velocity imaging(QTVI).Methods Twenty healthy controls and 24 patients with acute anterior myocardial infarction underwent QTVI with high-frame rates. The myocardial tissue velocity imaging in the apical 4-chamber view and apical 2-chamber view and apical longitude view were digitized and stored. Off-line ventricular walls regional velocity profiles along long axis were obtained, and systolic peak velocities (Vs) and early and late diastolic peak velocities (V E and V A) of 12 regional segments were measured.Results Under normal and ischemic conditions, 6 ventricular walls showed significant basal-apical myocardial velocity in the long-axis reduction in V S and V E and V A were significantly reduced in the abnormal segments in patients with MI. Conclusion QTVI can be used to analyze regional myocardial motion in the long-axis quantitatively and synchronously;intra-coronary stenting can obviously improve regional myocardial function of left ventricle,especially the diastolic function.
7.Experimental study on ischemic injury of certical spinal cord after acute artery block
Qizhi SUN ; Xianjun REN ; Hongwei HU
Orthopedic Journal of China 2006;0(20):-
[Objective]To study the effect on ischemic injury of cervical spinal cord(CSC) by comparison on two different blocks of arteries supplying CSC.[Method]Forty-eight rabbits were divided into two groups: Group A,ligation and section of anterior cervical spinal cord artery(ASCA);group B ligation and section of both ACSCA and bilateral vertebral arteries before its entramce the foraman(indirect block of Anterior cervical radicular artery(ACRA).Bdood flow changes of CSC were meansured after 6 h,24 h and 72 h(each N=6) and muscle motor cooked potential(MMEP),local energy metabolism,and cell morplotogical changes of CSC were observed.[Result]In group A,blood flow of CSC was going down markedly and showed 50.2% decrease,but got partial recovery at 24 h and 72 h.Delitescence of MMEP prolongcd,ATP and EC descended profressivtly,showing an ischemic changes,In group B there showed greate,changes about every observation thay that in group A with significant difference at every time poinl between two groups(P
8.Correlation of Physical and Mental Health with Coping and Defensive Style in Asthma Patients
Yanyu WANG ; Hongwei SUN ; Yuping SONG
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(01):-
Objective To explore the association of physical and mental health with coping and defensive style in asthma patients. Methods 190 adult patients with asthma were investigated with trait coping style questionnaire, defensive style questionnaire and short form 36 health survey questionnaire. Results The scores in group with higher score of health status were lower than those in group with lower score of health status in negative coping style, immature and middle defensive style, but higher in positive coping style (P
9.Expression and significance of Skp2 and Cx43 in cervical carcinoma
Zhen LIANG ; Lixin SUN ; Hongwei ZHAO
Cancer Research and Clinic 2010;22(12):840-842
Objective To investigate the expression of Skp2 and Cx43 in cervical carcinoma and to study their relationships and clinical significance. Methods The expression of Skp2 and Cx43 was examined by immunohistochemical method in 48 cases of cervical carcinoma tissue, 84 cases of cervical intraepithelial neoplasia (CINⅠ - Ⅱ 45 cases, CINⅢ 39 cases), 28 cases of chronic cervicitis. Results Skp2 expression in cervical carcinoma was higher than that in the CINⅠ - Ⅱ and chronic cervicitis (P <0.05), Cx43 expression was lower in cervical carcinoma than that in the CINⅢ, CINⅠ - Ⅱ and chronic cervicitis (P <0.05). The expression of Skp2 was correlated with histological differentiation and lymph node metastasis (P <0.05). The expression of Cx43 was correlated with the lymph node metastasis (P <0.05). Besides, the expression of Skp2had a negative correlation with that of Cx43. Conclusion Skp2 and Cx43 may play an important role in the genesis and development of cervical carcinoma.
10.The moderate effect of work control on the work stress-job satisfaction relationship and work stress-organizational citizenship behavior relationship
Qing HU ; Hongwei SUN ; Guoshan LI
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(8):732-734
Objective To explore the moderate effect of work control on the work stress-organizational citizenship behavior relationship and work stress-job satisfaction relationship.Methods 200 employees of five corporations in Shandong province were surveyed by questionnaires using work control scale,work stress scale,organizational citizenship behavior scale and job satisfaction scale.Results Work stress was negatively correlated with job satisfaction(r=-0.28,P<0.01)and organizational citizenship behavior(r=-0.25,P<0.01).Job satisfaction was significantly higher for employees who perceived high work control under certain work stress(β=0.16,P<0.05).The relationship between work stress and organizational citizenship behavior was significantly stronger for employees who perceived high work control under certain work stress(β=0.19,P<0.05).Conclusion The final results showed that work stress Was negatively correlated with organizational citizenship behavior.Work control had a positively moderate effect on the relationship between work stress and organizational citizenship behavior and the relationship between work stress and job satisfaction.