1.Research on Emotional Status and Activity and Participation for Inpatients with Spinal Cord Injury
Chinese Journal of Rehabilitation Theory and Practice 2017;23(8):946-949
Objective To analyze the relationship between the status of anxiety and depression and activity and participation for inpa-tients with spinal cord injury (SCI). Methods From January, 2014 to June, 2016, a total of 37 inpatients with SCI were assessed by Zung Self-rating Anxiety Scale (SAS), Zung Self-rating Depression Scale (SDS), and WHO Disability Assessment Schedule 2.0 (WHO-DAS 2.0) at discharge. Results The average scores of SDA were (0.5±0.18) and SAS were (41.15±14.7) respectively. The inpatients scored (1.43± 0.82) (cognition), (3.06±1.43) (mobility), (2.47±1.11) (self-care), (2.13±0.66) (getting around), (3.68±1.32) (life activity for household and work), and (3.57±0.84) (participation) in six domains of WHO-DAS 2.0 respectively. There were severe disabilities in mobility, life activity for household and work, and participation;mild disability in cognition;and moderate disabilities in self-care and getting around. There was positive correlation between depression and functions of mobility, life activity for household and work, and participation (P<0.05). Conclu-sion Depression influences the status of activity and participation for inpatients with SCI at recovery stage.
2.Effects of Tonifying Kidney-Yin on the Activities of Embryonic Stem Cell
Hongmei AN ; Bing HU ; Yunfeng SHI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
Objective To study the effects of tonifying kidney-yin on activities of embryo stem cell. Methods Embryonic stem cell line CRL-1825 was choosed as model cell in present study, and tonifying kidney-yin herb serum was added to CRL-1825 cell. The influence of tonifying kidney-yin on stem cell differentiation, cell cycle, apotosis and express of key genes were observed. Results Tonifying kidney-yin can inhibit stem cell differentiation and apotosis, promote stem cell proliferation and progression of cell cycle. In addition, tonifying kidney-yin can up-regulate Wnt, Oct4 gene expression, and down-regulation P16INK4a expression. Conclusions Tonifying kidney-yin can promote stem cell proliferation and maintain the state of stem cell.
3.Clinical significance of serum sICAM-1 levels in patients with colorectal carcinoma
Hana YU ; Hongmei SHI ; Yinglan ZHANG
Cancer Research and Clinic 1999;0(05):-
Objective To investigate the relationship between sICAM-1 and colorectal carcinoma metastasis. Methods ELISA was used to detect sICAM-1 level in specimens from 50 cases colorectal cancer patients' serum and 30 cases controls. Results Serum sICAM-1 level in colorectal cancer was significantly higher than that in controls (P 0.05), that in patients with metastasis was significantly higher than that in control(P
4.Application of solution focused approach in nursing of patients with ad-vanced schistosomiasis
Hongmei WANG ; Weimin SHI ; Zhiqiang QIN
Chinese Journal of Schistosomiasis Control 2016;28(3):316-318
Objective To investigate the effect of nursing with solution focused approach in advanced schistosomiasis pa?tients. Methods Fifty three patients with advanced schistosomiasis in the Liujiahu Hospital for Schistosomiasis Control of Yiyang City were randomized selected and separated into an intervention group and a control group. The patients of the interven?tion group received the conventional nursing plus solution focused approach,while the patients of the control group received on?ly the conventional nursing. The effectiveness of nursing and treatment was evaluated in the two groups comparatively. Results The knowledge of self?care skills,medical compliance behaviors and services satisfaction degree in the intervention group were higher than those in the control group(c2=3.78,2.87,4.09 respectively,all P<0.05). The occurrence rate of upper gastroin?testinal bleeding in the intervention group was significantly lower than that in the control group(c2=4.894,P<0.05). The aver?age hospitalization duration of the intervention group was shorter than that of the control group(t=4.17,P<0.05). Conclu?sions The solution focused approach is a feasible and effective method in course of nursing of advanced schistosomiasis pa?tients. It enhances the confidence of the patients and the trustiness of the patients to the health care providers. The complications and the hospitalization duration of the patients are reduced.
5.The research on the immuno-modulatory abilities of myelodysplastic syndromes patients bone marrow derived mesenchymal stem cells
Xishan ZHU ; Wei SHI ; Hongmei ZHANG
Chinese Journal of Microbiology and Immunology 2012;32(5):449-454
Objective To investigate that whether the immuno-modulatory capacity is intact in myelodysplastic syndrome-refractory anemia (MDS-RA) derived mesenchymal stem cell (MSCs) and what are the differences compare with those from normal donors.Methods Isolating MSC from MDS and normal donors respectively and exam their differences on T lymphocyte activation,proliferation and suppression.Results The results showed that the capacity of suppressing T cell proliferation and activation is weakened.Conclusion We propose that MSCs from pathological environment might be abnormal and should not be used for autologous transplantation.
6.Functioning and Disability for Patients with Spinal Cord Injury or Traumatic Brain Injury:Accessed with WHO Disability Assessment Schedule 2.0 Chinese Version
Hongmei SHI ; Ming WU ; Anqiao LI
Chinese Journal of Rehabilitation Theory and Practice 2017;23(6):741-744
Objective To study the activity and participation status of patients with spinal cord injury or traumatic brain injury. Methods From 2013 to 2016, 60 patients with spinal cord injury and 38 patients with traumatic brain injury were assessed with WHO Disability As-sessment Schedule 2.0 (WHO-DAS 2.0) (International Chinese Version of fully structured interviewer administered 36 questions). Results The patients with traumatic brain injury had moderate dysfunction in domains of cognition and getting along with people, and severe dys-function in other domains. The patients with spinal cord injury had mild dysfunction in domain of cognition, moderate dysfunction in do-mains of self-care and getting along with people, and severe dysfunction in other domains. The dysfunction was severer in domains of cogni-tion and self-care in the patients with traumatic brain injury than in the patients with spinal cord injury (t>2.140, P<0.05). Conclusion The inpatients with spinal cord injury and traumatic brain injury are difficult in mobility, self-care, getting along with people, life activities and participation.
7.Therapeutic Observation of Lao Shi Jiu plus Chinese Medication for Gastritis Due to Deficient Cold in Spleen-stomach
Guochen SHI ; Hongmei CHEN ; Bo ZHANG
Shanghai Journal of Acupuncture and Moxibustion 2017;36(8):939-942
Objective To observe the clinical efficacy of Lao Shi Jiu (moxibustion at a group of ten acupoints) plus Wu Zhu Xiang Sha Liu Jun decoction in treating chronic gastritis due to deficient cold in spleen-stomach. Method Ninety patients with chronic gastritis due to deficient cold in spleen-stomach were randomized into a moxibustion-medication group and a Western medication group by using the random number table, 45 cases each. The moxibustion-medication group was intervened by Lao Shi Jiu plus Wu Zhu Xiang Sha Liu Jun decoction, while the Western medication group was prescribed with conventional medications. The clinical efficacy and changes in symptoms were observed after the intervention. Result The total effective rates were respectively 88.9% and 75.6% in the moxibustion-medication group and Western medication group, and the rate in the moxibustion-medication group was significantly higher than that in the Western medication group (P<0.05); the gastroscopy-based total effective rates were respectively 91.1% and 77.8% in the moxibustion-medication group and Western medication group, indicating that the moxibustion-medication group was superior to the Western medication group (P<0.05); the improvement of stomachache in the moxibustion-medication group was more significant than that in the Western medication group (P<0.05). Conclusion The moxibustion-medication group is superior to the Western medication group in comparing the clinical efficacy and improvement of symptoms in treating chronic gastritis due to deficient cold in spleen-stomach.
8.Change of 8 iso PGF2a in chronic obstructive pulmonary disease and its significance.
Hongmei SHI ; Bingxiang TANG ; Guolong ZHANG
Chinese Journal of Practical Internal Medicine 2006;0(22):-
Objective To investigate the role of 8 iso PGF2a in patients with chronic obstructive pulmonary disease(COPD).Methods Level of serum 8 iso PGF2a and lung function were studied in 38 patients with acute exacerbation of COPD(AECOPD),23 patients with stable COPD and 18 health subjects.Results The serum 8 iso PGF2a level was significantly higher in patients with AECOPD[(6.84?1.70)?g/L]as compared to those in the controls[(4.64?1.24)?g/L]and in patients with stable COPD[(5.82?1.72)?g/L](P
9.Analysis of serum homocysteine levels in patients with colorectal cancer
Yinglan ZHANG ; Hongmei SHI ; Ningfang FAN ; Yujiao FENG ; Yan KANG
Cancer Research and Clinic 2012;24(8):550-552
Objective To investigate the changes of serum homocysteine (Hcy) level before and after treatment in patients with colorectal cancer,and provide the reference for clinical therapeutic efficacy and prognosis.Methods Enzymatic circling assay was used to measure the serum Hcy levels in 50 controls and 58 patients with colorectal cancer before and after treatment with a.follow-up of 12 months.The changes of Hcy aud the relationship between Hcy and therapeutic efficacy or prognosis were analyzed.Results Scrum Hcy level in patients with colorectal cancer was significantly higher than that in controls [(16.90±5.35) μmol/L vs (10.23±3.06) μmol/L] (P < 0.01),and it was closely associated with TNM stage.Serum Hcy level in patients of stage Ⅲ-Ⅳ was significantly higher than that of stage Ⅰ-Ⅱ [(18.49±5.13) μmol/L vs (15.20±4.86) μmol/L] (P < 0.05).The Hcy level in patients at the end of treatment was significantly lower than that before treatment [(13.39±4.98) μmol/L vs (16.90±5.35) μmol/L] (P < 0.01),and the Hcy level after the treatment for 3 month was significantly lower than that at the end of treatment [(10.23±3.17) μmol/L] (P < 0.05).The Hcy level in patients with recurrence during 12 months after operation was significantly higher than that without recurrence [(17.18±4.82) μmol/L vs (12.36±3.19) μmol/L] (P < 0.01).Conclusion Serum level of Hcy might be a useful marker for predicting therapeutic efficacy and prognosis in patients with colorectal cancer.
10.Psychological and Behavior Barriers and Psychological Rehabilitation Strategies for Natural Disaster Survivors
Zhuoying QIU ; Huizhong HUANG ; Junmei ZHANG ; Hongmei SHI ; Jie ZHU
Chinese Journal of Rehabilitation Theory and Practice 2008;14(7):673-676
This paper will address the development of disaster psychology and its important contribution regarding its theoretical and practical frameworks as it applies to the psychological counseling for survivors suffering from the consequences of natural disasters.This paper will also analyze how the approach of disaster psychology can be applied to work with survivors suffering from natural disasters and to alleviate psychological challenges and its influential factors which affect these individuals.Several strategies have been discussed and proposed.In addition,relevant theoretical and integrated approaches for psychological intervention support and guidance,and rehabilitation have been established.