Objective: To analyze the imaging features of mycoplasma pneumonia in order to improve the early diagnosis and treatment of mycoplasma pneumonia as well as reduce misdiagnosis. Methods:Multislice CT data of 31 mycoplasma pneumonia patients during 2012.4 to 2014.4 in our hospital were retrospectively analyzed. Results:Multislice CT results showed that 22 cases(70.97%) occurred in one side of lung, in which 12 cases (38.71%) located in the left lung(two cases located in the lobi superior(6.45%)and 10 cases located in the lobi inferior(32.26%));10 cases (32.26%) located in the right lung , in which 4 cases located on the lobi superior (12.90%), four cases at the lobi inferior(12.90%), two cases involved both lobi medius pulmonis and lobi inferior(6.45%). 9 cases (29.03%) were double lung involvement. The changes of CT are diverse which included glass-like images, consolidation, air bronchogram, bronchial vascular bundle thickening, pleural effusion and mediastinal lymph nodes enlargement. Conclusion:Patients with mycoplasma pneumonia always have varied radiographic changes and chest multislice CT has a certain sense of early diagnosis.

Objective To investigate the expression of Survivin,receptor for advanced glycation endproduct(RAGE) and high mobility group protein B1 (HMGB1) gene in human breast cancer and their clinical significance.Methods The expression of Survivin,RAGE and HMGB1 gene was detected by Real-time PCR technology and fluorescence in situ hybridization (FISH) technology in the following tissue samples:50 early breast cancers,50 advanced breast cancers,and the corresponding adjacent normal mammary tissues.The relationship of their expression and several factors such as differentiation degree,invasion,lymph node metastasis and TNM stage of cancer was explored.Results The positive expression rate of Survivin,RAGE and HMGB1 gene was 62％,73％ and 79％ detected by Real-time PCR technology,78％,69％ and 72％ detected by FISH technology in breast cancer tissues.The overexpression of these genes was positively correlated with TNM stage and lymph node metastasis.The expression of Survivin gene was positively correlated with the expression of RAGE and HMGB1.Conclusion Overexpression of Survivin,RAGE and HMGB1 gene is of great significance in early diagnosis and prognosis of human breast cancer.

Ohjective To investigate the expression of Survivin gene in human breast cancer and its clinical significance.MethodsReal-time PCR technology and fluorescence in situ hybridization (FISH) technology were employed to detect the expression of Survivin gene in the following tissue samples:50 breast cancers in stage Ⅰ and Ⅱ,50 breast cancers in stage Ⅲ and Ⅳ,and the corresponding adjacent normal mammary tissues.The relationship of Survivin gene expression and several factors such as differentiation degree,invasion,lymph node metastasis,TNM stage was explored.ResultsThe positive expression rate of Survivin gene was 62％ and 78％ respectively detected by real-time PCR and FISH in breast cancer tissues.The overexpression of Survivin gene was positively correlated with TNM stage and lymph node metastasis.ConclusionsOverexpression of Survivin gene can be used as one of the parameters in early diagnosis and prognosis of human breast cancer.Selective gene therapy based on these gene expressions may be useful.