Breast cancer was a common malignancy in female and endangered their health seriously.In recent years,the incidence of breast cancer has been more and more and younger and younger.With breast cancer checked out widely,the diagnosis rate of the early breast cancer has been significantly increased,so that the prognosis of patients with breast cancer has been apparently improved.Currently,the majority of patients did not only require removing the total tumor completely,but also ensuring tihe quality of life to reduce the psychological pressure.What's morc,they required a better cosmetic result.Thus the conventional treatments (such as surgery,radiotherapy,chemotherapy,estrogen and progesterone) have not met their pursuit; the radiofrequency ablation is a better therapeutic method.I briefly describe its principlcs,methods,status,postoperation,complication and so on.

OBJECTIVE: To evaluate the therapeutic effects and cost-effectiveness of 3 therapeutic regimens in the treatment of gonarthritis. METHODS: The cost-effectiveness analyses were conducted among 3 therapeutic regimens: regimen A(sodium hyaluronate), regimen B(sodium hyaluronate plus compound betamethasone) and regimen C(sodium hyaluron_ate plus triamcinolone acetonide acetate). RESULTS: The total costs for Group A, B and C were 956.5 yuan, 1 206 yuan and 998.5 yuan, respectively. The effective rates were 79.2%, 91.3% and 96.4%, respectively. The cost-effectiveness ratios were 12.08, 13.21 and 10.36 respectively. As compared with regimen A, the incremental cost-effectiveness ratios for regimen B and C were 20.62 and 2.44 respectively. CONCLUSION: Regimen C is more preferable among the three therapeutic regimens.

Objective:To analyze the application of antidepressants in our hospital in order to provide some reference for clinical rational drug use.Method:The antidepressants used in our hospital from 2006 to 2008 were classified by construction and mechanism and statistically analyzed in DDDs frequency.Result:Among the antidepressants used in our hospital,SSRIs were first-choice drugs,and venlafaxin of SNRIs dominated the first place in terms of use frequency and amount. Conclusion:Antidepressants used in our hospital were basically rational.

0.05). In the field of side effects,especially EPS,weight gain,lactation and menstrual disorders,aripiprazole was significantly lower than risperidone(P

Breast cancer has become one of the most common malignant tumors in female and endangered their health seriously.In recent years,the incidence of breast cancer continues to be uptrend and tend to be younger.As the treatment of breast cancer is more diversified and meticulous,the prognosis of breast cancer has been improved.When Dr Csatary found a farmer got gastric cancer was cured by Newcastle disease virus occasionally,Newcastle disease virus was widely studied as a novel kind of anti-tumor biologics.So Newcastle disease virus had become an effective new treatment method in breast cancer.This article briefly elaborates the profile of Newcastle disease virus,mechanism,the significance of researching and other aspects.

ObjectiveTo investigate theeffect of combining traditionalChineseandWestern medicine therepy for patients with hormone-dependent dermatitis.Methods The relative literature conceming the clinical trials in treating patients with hormone-dependent dermatitis with therapy of combining traditional Chinese and Western medicine between 2005 and 2011 were retrieved,and Meta-analysis was made on the qualified literature by means of Review Manager 5.0 software.Results 15 randomized trials with 1749 patients met inclusion criteria.Compared with western medicine treatment group,the test results of the effective rate on the patients with hormone-dependent dermatitiswiththerapyof combining traditionalChineseandWestem medicinewasZ =12,P＜0.00001,OR =4.2 ( 95％ CI,3.32 t0 5.31).ConclusionPatients with hormone-dependent dermatitis with therapy of combining traditional Chinese and Western medicine could get better therapeutic effect.

Objective To observe the effects of solanine on DNA and RNA level in tumor cell of S_(180) and H_(22) tumor-bearing mice.Methods S_(180) and H_(22) mice were divided into solanine(37.50、18.75,and(9.37) mg/kg) groups,negative control group and cytoxan(30 mg/kg) group,whom were given drugs by sc.Levels of RNA and DNA in tumor cell membrane in every groups were examined,respectively by laser scanning confocal microtechnic technology.Results Solanine(37.50、18.75 mg/kg) groups reduced the ratio of RNA and DNA in tumor cell of both S_(180) and H_(22) mice.Conclusion Solanine can reduce the ratio of RNA and DNA in tumor cell of S_(180) and H_(22) mice,which may be one of the mechanisms of solanine's(antitumor) effect.

Gastric cancer incidence is one of the most common malignancies in our country and is the second most common in the worldwide,clinic doctors always emphasize early diagnosis and treatment of gastric cancer patients,in order to reduce the mortality,however,most patients' condition often have been in the late fall and these patients were badly in efficacy.Looking for a new diagnosis way is a medical prddem,with molecular biology advance and gene chips was improved,it is possible for the early screening of gastric cancer.This assay aims to briefly analyse the role of gene chips in the research progress of early gastric cancer.

Objective To observe effects of Glycyrrhiza flavonoids on DNA and RNA in tumor cell of S_(180) and H_(22) tumor-bearing mice.Methods S_(180) and H_(22) mice were randomly divided into Glycyrrhiza flavonoids(25,11.25,and 5.58 mg/kg) groups,positive control(cytoxan 25 mg/kg) group,and negative control(NS) group,whom were given drugs by sc.DNA and RNA in tumor cells were examined,respectively by Laser Scanning Confocal Microscope and fluorescent probe of acridine orange(AO) technology.Results All different dosage of Glycyrrhiza flavonoids,cytoxan reduced the brightness of fluorescence of DNA and RNA;low and high dosage of Glycyrrhiza flavonoids had no significant effect on the fluorescence pixels of RNA/DNA;Both middle dosage of Glycyrrhiza flavonoids and cytoxan had significant effect on the fluorescence pixels of RNA/DNA(P

The theory of Constructivism was applied in different aspects of clinical teaching of surgery.The lessons were designed according to the character of students.Problem solving was emphasized during the course of teaching.An interactive and cooperative atmosphere was constructed.And a variety of additional related materials were provided.All these measures made the teaching activity more accord with the objective rule of clinical knowledge learning.Hence a better teaching effect was achieved.