1.Application of clinical nursing path in the swallowing training of stroke patients with neural deglutition disorders
Yushan YIN ; Weiying LIANG ; Honghua ZHUANG
Modern Clinical Nursing 2014;(2):23-26
Objective To study the effect of clinical nursing path(CNP)on the swallowing training of stroke patients with neural deglutition disorders.Methods Sixty stroke patients with neural deglutition disorders were recruited from January 2012 to October 2012 in the department of neurology of our hospital.The patients were divided into two groups according to the sequence of admission:the experiment group(n=30)and the control group(n=30).CNP was applied in the experimental group and the traditional nursing approach in the control.The two groups were compared in terms of the improvement of deglutition disorder.Result The effective rate of the experiment group was significantly higher than the rate of the control group(P<0.05).Conclusion CNP is effective in improving stroke patients’neural deglutition disorders and enhancing their life quality.
2.Clinical research on priming regimen CAG in treatment of acute myeloid leukemia in elderly
Zunchang LI ; Hongjie FU ; Mingdong SUN ; Honghua YIN ; Sheng YANG
Chinese Journal of Primary Medicine and Pharmacy 2011;18(17):2331-2332
Objective To explore the effect and adverse reaction of priming regimen CAG in treatment of acute myeloid leukemia in elderly.Methods 32 elderly patients with acute myelogenous leukemia were treated with CAG regimen and 25 cases with standard chemotherapy regimen( DA regimen). The effect and adverse reaction were compared between the two groups. Results There was no significant difference of the complete remission rate and effective rate between the two groups. The recovery time of bone marrow and death rate of CAG the regimen group were superior to those of the DA group. Conclusion CAG regimen was effctive and safe for elderly patients with acute myeloid leukemia.
3.The expression and signification of NET-1 in endometrial carcinoma
Xiaohua SONG ; Dianzhong GENG ; Honghua YIN ; Xia WANG
Journal of Chinese Physician 2012;14(1):27-30,33
ObjectiveTo study the expression and potential significance of NET-1 in endometrial carcinoma.Methods106 specimens after operation were selected.All specimens were stained with H.E.and immunohistochemistry.ResultsThe expression of NET-1 immunoreactivity were different in normal endometrium(43.8% ),endometrial hyperplasia ( 79.2% ) and endometrial carcinoma ( 100% ) ( x2 =11.88,P < 0.01 ).The expression of NET-1 in endometrial carcinoma was significantly higher than that in normal endometrium and simple endometrial hyperplasia ( x2 =36.14,10.86,P < 0.01 ).The expression of NET-1 in endometrial hyperplasia was significantly higher than that in normal endometrium ( x2 =5.29,P< 0.05 ).There was a correlation between the expression of NET-1 and degree of endometrial lesions ( r =0.355,P <0.01 ).The expression of NET-1 was relative with differentiation (x2 =11.04,P <0.01 ; r =0.558,P <0.01),stages(x2 =11.04,P <0.01; r =0.558,P <0.01),depth of myometrial invasion (x2 =15.90,P <0.01 ; r =0.479,P <0.01),with or without metastasis in lymph node ( Z =-3.74,P <0.01 ),menopause condition ( Z.=-2.60,P <0.01).ConclusionsNET-1 may play an important role in carcinogenesis and progression of endometrial carcinoma.It might be a marker of biological behavior and reference for endometrial carcinoma gene therapy.
4.Correlation of urine phthalate metabolite levels with blood pressure in first-grade children
Chinese Journal of School Health 2019;40(9):1356-1359
Objective:
To explore the correlation between blood pressure and urinary phthalandione, MMP, MEP, MnBP, MiBP, PAEs.
Methods:
Three schools were selected from Shenzhen, China for the present study. A total of 765 firstgrade students of Han ethnicity were recruited voluntarily from the selected schools during September 2016 to June 2017. They were divided into normal blood pressure (BP) group (lower than P90 group) and high BP group (BP≥P90). Linear and Logistic regression models were used to analyze the relationships between blood pressure and urine phthalate metabolite levels.
Results:
Urinary MMP and MnBP in students of high BP group were significantly higher than that of students in normal BP group(t=13.12, 3.97, P<0.05). Linear regression models showed that Z score increased when MMP and MnBP levels increased(P<0.05). Logistic regression model suggested that the risk of high BP increased with the increment of MMP level adjusting creatinine, sex, age and BMI(OR=1.47, P<0.05). There was no statistical significance in the differences after adjusting many factors including family income and education level of parents(P>0.05).
Conclusion
Urinary phthalate metabolite levels are positively associated with blood pressure in first-grade children.