Objective To explore the method of treatment on ventricular hemorrhage .Methods The clini-cal experience of 70 cases of ventricular hemorrhage with minimally invasive treatment of external ventricular drainage and injection of urokinase with CT stereotactic were summarized .Results Except for 3 cases of death ,67 cases sur-vived(95.7%),Grade Ⅰ-Ⅱwas 37 cases(52.9%),Grade Ⅲ was 21 cases(30.0%),Grade Ⅳ-Ⅴ was 9 cases (12.9%), and there was no complication of infection and bleeding associated with drainage among 70 cases. Conclusion The minimally invasive treatment of external ventricular drainage and injection of urokinase with CT ste -reotactic on ventricular hemorrhage improves the cure rate significantly ,reduces the mortality rate and the incidence of complications ,which has important clinical value .