Objective To investigate the curative effects of fluvastatin and its anti-inflammation mechanism in early diabetic nephropathy (EDN).Methods 140 patients with EDN were randomly divided into two groups,the control group (n=70) and the treated group (n=70).The control group received conventional therapy,while the treated group was added oral 40 microgram of fluvastatin every night.Compare the UAER,Scr and CRP 3,6 and 9 months later respectively.Results UAER and Scr had been decreased more significantly and quickly(three months earlier) in treated group than in control group. CRP had been decreased significantly in treated group,while no significant decrease had been found in control group during the follow-up of nine months.Furthermore,similar results were also obtained in those EDN with normolipidemia when further analyzed.Conclusion Fluvastatin can ameliorate microalbuminuria and improve renal function by its anti-inflammation effect by decreasing CRP,which is independent of its lowering lipidemia effect.

Objective To study dynamic response of serum lipid after fat meal in old persons with fasting TG≤1 70 mmol/L. Methods Using fat meal of 63 9 g/m 2 body surface area, TG, TC, HDL C and LDL C of both elderly and control groups in fasting status and 2, 4, 6 and 8 h after fat meal were determined. Results The TG value after fat meal was significantly higher than that in fasting status( P 0.05). Conclusions The expurgation of triglycerides is delayed in elderly people, meaning that the capacity for fat removal is decreased, and it is possibly the main cause of TG increase in the elderly.

Objective:To explore the relationship between false increase of white blood cell count and fragility of erythrocyte membrane in automatic whole blood count. Methods: The osmosis and incubation osmosis fragility of erythrocyte membrane in controls 1 (Group 1, n =30)and white blood cell count false increase (Group 2, n =30) were detected by the operation rule of the group of clinical examination. Results: Compared with the results of Group 1 frogility of erythrocy to membrane in infectious hepatitis,livercirrhosis and liver cancer were reduced( P

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