1.Five Steps Learning Method of Inner Canon of Huangdi
Journal of Zhejiang Chinese Medical University 2016;40(10):777-779
Objective] The primary objective of this article is to explore the learning method of Inner Canon of Huangdi and to improve the efficiency of studying classics of TCM. [Methods] To summarize the experience of teaching and participating in quiz of Inner Canon of Huangdi; to conclude reading, cognizing, identifying, mastering, and using into a five steps learning method; to elaborate the application and extending of every step. [Results] The five steps learning method is effective and practical, progressive and comprehensive. [Conclusions] Following the five steps learning method, learning process will be simplified, learning efficiency will be improved and learning achievement will be consolidated.
2.Interdisciplinary construction mode and effect analysis
Chinese Journal of Medical Science Research Management 2014;27(4):434-437
In this article,the strategy and achievements of the interdisciplinary in recent years in Peking University are summarized.We also discussed the remaining problems in the development of medical science and interdisciplinary as well as how to improve the management system and operational mechanism.
3.Morphological Observation of Intestine-clearing Suppository in Preventing and Treating Rats'Ulcerative Colitis
Hongbin ZHENG ; Hongyi HU ; Xiong LU
Journal of Zhejiang Chinese Medical University 2001;25(1):47-51
Observe and study the morphological changes and effects on yoleperoxidase (MPO) of traditional Chinese medical complex Intestine-clearing Suppository (ICS) in preventing and treating ulcerative colitis (UC).Method.. Divide the experimental rats randomly into 6 groups, i.e., blank, salicylazosulfapyridine (SASP), model, high, middle and low dosage of ICS, except the blank group, makeother rats experimental UC model with albumen immunologic method of rabbit colon mucosa, further divide them randomly into 2 experimental groups, i. e. , prevention and treatment, afterwards at 2nd~21st day, give prevention group the medicine, 22nd~35th day, treatment group, then decapitate them and take the colon tissue, and observe it morphologically under optical microscope, measure active MPO, analyse statastic results. Result: Through general morphological observation ,we found there were serious congestion ,edema, mucosa erosion, many large ulcers in the rats of model group; less serious mucosa erosion and quantity of ulcers in SASP and low-dosage ICS groups: small ulcers, not serious mucosa erosion, low degree of congestion and edema in high-and middle-dosage ICS groups; the scores of inflammatory injury of ICS groups were markedly lower than that of model (P<0. 01), meanwhile, the preventive and reating effectiveness of high-and middle-dosage groups was better than that of SASP (P<0.05). Under the optical microscope, there were large area of mucosa coloboma in the rats of model group, the ulcer penetrated to muscular layer and serous coat; in SASP group and low-dosage ICS group, there were erosive mucosa and inflammatory cell infiltration, granulation on the base; in middle-and high-dosage groups, large part of colon mucosa recovered, granulation formed on the base, ulcers were obviously less than that in model group (P <<0.01); there had marked difference compared with that in SASP group (P<0.05). The MPO active values of high-and middle-dosage groups were markedly lower than that of model group (P < 0.01). Conclusion: Traditional Chinese complex ICS had good prevention and treatment to rats UC, itseffectiveness was positively correlated with dosage and better than that of SASP suppository.
4.The Effect of Gaoyuankang Capsule on the Serum NO Content and Plasma ANP, CGRP and ET Content in Entrants Landing at High Altitude Rapidly
Suzhi LI ; Bihai ZHENG ; Hongbin WANG
Journal of Chinese Physician 2001;0(02):-
Objective To study the effect of Gaoyuankang capsule on the serum nitric oxide (NO) content and plasma atrial natriuretic peptide(ANP), calcitonin gene-related peptide(CGRP) and endothelin(ET) content in great numbers of entrants landing at high altitude rapidly and its significance. Methods 2150 new soldiers, who swiftly entered plateau by air from plain, were randomly divided into experimental group (EG,n=1150) and control group (CG,n=1000). EG continually orally took Gaoyuankang capsules for 3 days before boading a plane. CG orally took placebo. The changes of serum NO content and plasma ANP, CGRP and ET content before and after entering plateau, and the incidence of acute high altitude disease (AHAD) after entering plateau were compared between the two groups, each group containing 40 randomly selected soldiers. Results NO and CGRP concentration of CG remarkably decreased after entering plateau than before entering plateau, while ANP and ET levels remarkably increased after entering plateau than before entering plateau (P
5.Management of Oxygen and Clinical Safe Use in Our Hospital
Hongbin FAN ; Xiaoyan WU ; Ying ZHENG
Chinese Medical Equipment Journal 2004;0(09):-
Standardized management and safe-supply system can be enhanced by oxygen chamber management rules,oxygen safe -supply management,daily maintenance of oxygen supply,solutions on common malfunctions and the management of oxygen humidifier. The importance of the management of oxygen is discussed and the regulations should be strictly abided to reduce accident. The oxygen used on clinic can be standardized to ensure the safe-supply.
6.DNA microarray technology and its application advances in articular cartilage research
Xuhong XUE ; Qixin ZHENG ; Hongbin WU
International Journal of Biomedical Engineering 2009;32(6):359-362,370
DNA microarray generally refers to gene chips. Its basic principle is that a large number of oligonucleotide molecules were fixed on the support, and then hybridized with the labeled samples, and then the chip hybridization signal strength was scanned to determine the number of target in the samples. Gene chips can trace the nucleotide sequence in the samples for testing and analyzing. Its characteristics of high-throughput,rapid and parallel acquisition of biological information are better than that of other traditional gene detection technology. It has been widely used in various fields of medical research. This article reviews the application of DNA microarray technology in the study of orthopedics including biological characteristics, formation and development,injury and repair, degeneration and regeneration of articular cartilage.
7.Influence of Qingchangyukui Gel on Activity of SOD and Contents of MDA in Rats with Experimental Ulcerative Colitisbstract
Hongbin ZHENG ; Erning GE ; Yixun ZHANG
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective] To observe the curative effects and the influence of activity of Superoxide dismutase(SOD) and contents of Maleic dialdehyde(MDA) of Qingchangyukui Gel in Rats with Experimental Ulcerative Colitis. [Method]Ulcerative Colitis model was established in Wistar rats by injecting trinitro-benzene-sulfonic acid (TNBS)into anus, and then treated with Qingchangyukui Gel and salisy-lazosulfa-pyridine(SASP) respectively. Isolating the colon and measuring the SOD and MDA after treating for two weeks. [Results]Colon mucous membrane in the model group had serious erosion, ulcer, damaging of glandular organ, high inflammation grade; activity of SOD in model group was significantly lower than in normal group and contents of MDA increased. The other groups, especially in Qingchangyukui Gel group, had different levels of inflammation repairing, ulcer healing, increasing of SOD and reducing of MDA. [Conclusion]TNBS can cause Colon mucous membrane inflammation and ulcer, reducing of SOD and increasing of MDA , which are the typical pathological change of Ulcerative Colitis; the Qingchangyukui Gel has the effects of increasing the activity of SOD and reducing contents of MDA, therefore it can effectively treat the UC rat.
8.Effects of Chemotherapy Plus Rhodiola L. on Immunofunction of Tumor Patients
Jianrong WU ; Ling ZHENG ; Hongbin ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
0.05).Conclusion The immunofunction was impaired considerably by chemotherapy.Rhodiola L.can enhance the immunofunction considerably.
9.Effect of Neural Stem Cells Transplantation on Sequela after Traumatic Intracranial Hematoma
Hongbin CHENG ; Shaoshan HU ; Yongri ZHENG ; Min LI ; Yihua AN
Chinese Journal of Rehabilitation Theory and Practice 2007;13(5):454-455
Objective To investigate the curative effect of neural stem cells (NSCs) transplantation on sequela after traumatic intracranial hematoma. Methods 20 patients with sequela after traumatic intracranial hematoma were treated with NSCs transplantation. Cells were engrafted into subarachnoid cavity via lumbar puncture. They were assessed with Functional Independence Measure (FIM) before and half a year after the transplantation. Results The FIM scores were significantly increased after the transplantation (P<0.01).Conclusion NSCs transplantation could promote functional recovery and improve the living quality of patients with sequela after traumatic intracranial hematoma in the aspects of self-care, sphincter control, mobility, locomotion, communication and social adjustment/cooperation.
10.Practice and effect analysis of interdisciplinary development at medical colleges
Yurong ZHENG ; Hongbin HAN ; Ruqun SHEN ; Weigang FANG
Chinese Journal of Medical Science Research Management 2013;(2):123-125
Research collaboration and interdisciplinary integration is anecessary trend of the development of science and technology,and is especially true in biomedical field.This paper describes the interdisciplinary practice of the projects at Peking University Health Science Center in recent years.Problems and the efficiency of the management is also analysed.