1.Mid- and long-term outcome of coronary artery bypass grafting in patients with severe left ventricular systolic dysfunction
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(03):-
Objective To evaluate the mid- and long-term results of coronary artery bypass grafting (CABG) in patients with severe left ventricular systolic dysfunction. Methods Between January 1988 and December 2002, 34 cases with left ventricular ejection fraction (LVEF) less than 0.30 underwent CABG. They were aged 41 to 73 years [mean, (58.0?9.4) years], and 30 of them were male. Coronary angiography revealed LVEF was 0.15 to 0.30(mean, 0.27?0.04), and triple-vessel disease in 31 cases, and left main stem disease in 4. Preoperative echocardiographic examinations revealed a mean of left ventricular diastolic dimension (LVDD) (61.5?8.9) mm and LVEF 0.28?0.07. New York Heart Association (NYHA) class was (2.9?0.7). Off-pump CABG was performed in 8 cases. The number of grafts used ranged from 2 to 6 (3.9?0.9). 32 patients (94.1%) were followed up for 3.5 years (with 7.2 years maximum). Results No patients died in hospital. Heart failure as the main postoperative complications were observed in 5 (14.7%) patients. Postoperative echocardiographic examinations revealed a mean LVDD of (55.2?7.1) mm and LVEF of 0.47?0.11. NYHA class was1.9?0.3 postoperatively. In the follow-up period [mean (3.5?1.9) years], 3 patients died. The survival rates were 91.9% at 3 years and 85.7% at 5 years. Functional status improved significant in left ventricular end-diastolic diameter and left ventricular ejection fraction. There was significant improvement in mean NYHA from class 2.9?0.7 to 1.4?0.6 postoperatively. 26 survivors (81.3%) are free of angina. Conclusion Observations suggest that CABG may offer a better quality of life in patients with poor ventricular systolic function in mid- and long-term follow-up. Preoperative management was the key point of the survival advantage.
2.Maxillary first molar with twin-root canal in palatal side: two case reports.
West China Journal of Stomatology 2015;33(3):329-330
Maxillary first molar with twin-root canal in palatal side is rare. This article described two cases of maxillary first molar with twin-root canal. A properly designed and prepared access of the cavity is helpful for the diagnosis and negotiation of the root canal morphology.
Dental Pulp Cavity
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Humans
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Maxilla
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Molar
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Root Canal Therapy
3.Transcutaneous Injection of MIIGX3 Artificial Bone and Methylprednisolone for Treatment of Recurrent Bone Cysts
Hongbin WU ; Jingyuan DU ; Shuhua YANG
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To investigate the efficacy of transcutaneous injection of MIIGX3 artificial bone and methylprednisolone for recurrent bone cysts.Methods From January 2004 to March 2006,a total of 13 children with recurrent bone cysts received transcutaneous injection of methylprednisolone and MIIGX3 in our hospital.X-ray was employed to detect the degradation of MIIGX3 and formation of new bones.Results The operation time ranged from 30 to 95 minutes(mean 42 minutes).The patients were followed up for 1 to 3 years.None of them had recurrence of bone cysts during this period.The artificial bones were completely degraded and replaced by new bones in 1.5 years after the injection.Conclusions Transcutaneous injection of methylprednisolone and MIIGX3 is effective for recurrent bone cysts.Patients have shorter operation time and hospital stay after this treatment because the procedure is microinvasive.
4.DNA microarray technology and its application advances in articular cartilage research
Xuhong XUE ; Qixin ZHENG ; Hongbin WU
International Journal of Biomedical Engineering 2009;32(6):359-362,370
DNA microarray generally refers to gene chips. Its basic principle is that a large number of oligonucleotide molecules were fixed on the support, and then hybridized with the labeled samples, and then the chip hybridization signal strength was scanned to determine the number of target in the samples. Gene chips can trace the nucleotide sequence in the samples for testing and analyzing. Its characteristics of high-throughput,rapid and parallel acquisition of biological information are better than that of other traditional gene detection technology. It has been widely used in various fields of medical research. This article reviews the application of DNA microarray technology in the study of orthopedics including biological characteristics, formation and development,injury and repair, degeneration and regeneration of articular cartilage.
5.Effects of Chemotherapy Plus Rhodiola L. on Immunofunction of Tumor Patients
Jianrong WU ; Ling ZHENG ; Hongbin ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
0.05).Conclusion The immunofunction was impaired considerably by chemotherapy.Rhodiola L.can enhance the immunofunction considerably.
6.The clinical application of percutaneous vertebroplasty on bone metastatic tumor
Jianxin LIU ; Biao LI ; Hongbin WU
Journal of Interventional Radiology 2006;0(11):-
Objective To study the primary volume of bone cement and the method of perfusion and the clinical effect of percutaneous vertebroplasty for bone metastatic tumors. Methods Percutaneous vertebroplasty was performed in 218 vertebral bodies of total 150 patients,including 92 males and 58 females with age of 26-85,averaging 56.8 y. 218 vertebral bodies included 73 dorsal vertebra and 138 lumber vertebra and 7 sacral vertebra. Operations were taken under the DSA monitoring. The approach route was selected according to the morphology of the vertebrae,damage extent and puncture site. Results Operation was successful in all 218 vertebrae of total 150 patients with a ratio of 100%. The primary volume of bone cement needed to fill dorsal vertebra was 2-5 ml,average 3.5 ml; that for lumber vertebra was 3-8 ml,average 5.5 ml; and that for sacral vertebra was 4-7,average 5.5 ml. 134 patients showed total pain relief (89.3%); 15 patients had partial remission (10%) and 1 failure (0.7%). The cement extravasated to intervertebral disk in 12 patients,to scleromeninx capsula externa in 10,to para-vertebra plexus venosus in 3 and to paravertebra soft tissue in 4. The incidence of leakage of bone cement was 13.3%,but no complications occurred during and after the operation. Concolusion Percutaneous vertebroplasty provides obvious pain relief effect for vertebral metastasis,worthy to be recommended widely in clinical application.
7.Video-assisted thoracoscopic surgery (VATS) combined with auxiliary mini-incision for the treatment of 54 patients with thoracic injury.
Hongbin QIN ; Jingfa LIU ; Bin WU
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To explore the possibility of expending indications of VATS though auxiliary mini-incision. Methods 54 patients with thoracic injury underwent pulmonary lobectomy or pulmonary wedge resection or pulmonary rupture repair or diaphragm rupture repair using VATS combined with auxiliary mini-incition. Results All of 54 patients were cured. with primary wound healing .Hospital stay was 8d~10d with a mean of 10d.. No complication occurred. Conclusions VATS combined with auxiliary mini-incision could provide a possibility of simultaneous diagnosis and treatment and obtains as the same therapeutic result as conventional open surgery and expends indication of VATS.
8.Experience about treatment of segmental and comminuted femoral fractures in multiple injuries
Weiguo XU ; Yinghua WU ; Hongbin JIN
Orthopedic Journal of China 2006;0(08):-
[Objective]To summarize the experience about treatment of segmental and comminuted femoral fractures with intramedullary nail in multiple injuries.[Method]From March 2002 to July 2006,28 patients with segmental and comminuted femoral fractures were treated surgically,13 with AO type C1,9 with C2 and 6 with C3.All of the fractures were treated with close reduction static intramedullary nail fixation.[Result]The postoperative follow-up ranged from 11 to 34 months with an average of 21 months.All of the fractures were healed.Limit load was required for 5 patients who had delayed union without special treatment.After 18-30 months the patients healed up.There were no fat embolisms.No complications such as infection,intramedullary bending or break occurred.[Conclusion]Treatment of femoral fractures with intramedullary nail is a standard method.However,to achieve satisfactory results,comprehensive treatment,careful planning and procedure should be taken for segmental and comminuted femoral fractures in multiple injuries.
9.External fixator combined with vaccum sealing drainage for the infection after internal fixation in tibial and fibular fracture
Fan DING ; Zengwu SHAO ; Hongbin WU
Orthopedic Journal of China 2006;0(08):-
[Objective]To explore the effect of external fixator combined with vaccum sealing drainage(VSD) for the treatment of infection after internal fixation in tibial and fibular fracture.[Method]Thirty-six patients with infection after internal fixation in tibial and fibular fracture were treated by external fixator combined with VSD from June 2004 to June 2008.[Result]During the following-up period from 8-30 months in thirty-two patients,the infection in all cases were controlled effectively,no case of recurrence was found in all patients,and satisfactory healing were found in 32 cases.The average time of fracture union were 4.5 months;the removal time of external fixation were 5 months on average.[Conclusion]The combined operative procedure is simple,reliable and less traumatic and allow to early functional exercises.Therefore,it is a satisfactory measure for the infection after internal fixation in tibial and fibular fracture.
10.Treatment of nonunion after Pilon fracture with fibula approach fixation of tibia and ankle joint fixation
Weiguo XU ; Hongbin JIN ; Yinghua WU
Orthopedic Journal of China 2006;0(20):-
[Objective]To investigate the treatment of nonunion after Pilon fracture with fibula approach fixation of tibia and ankle joint fixation and its clinical efficacy.[Method]Six cases of nonunion after Pilon fracture were collected from 1999 to 2004,which included 4 males and 2 females,with the average age of 34.7 years(21~53 years).All fractures were found invasion to the tibia-fibula joint and ankle malformation.Fibula and tibia were opened from posterolateral approach and reconstruction plate was placed laterally on the fibula,with screws crossing the fibula into the tibia directly.Autogenous bone graft was used in fracture position and area between tibia and fibula to gain tibia-fibula fusion.[Result]All cases were followed up from 8 months to 4 years with the average of 22 months.Bone fusion were gained in 5 cases with the average time of 3.5 months.Plate broken was found in 1 case for too early weight bearing.[Conclusion]Fibula approach fixation of tibia and ankle joint fixation has advantages of promoting fracture healing,preventing complications,and correction joint malformation.It is a convenient and reliable method for clinical surgeons.