1.Endovascular stenting for symptomatic stenosis of middle cerebral artery
Qinghai HUANG ; Jianmin LIU ; Bo HONG
Journal of Interventional Radiology 1994;0(03):-
Objective To summarize the early experience and results of endovascular stenting for symptomatic stenosis of middle cerebral artery. Methods We performed percutaneous endovascular stent assisted angioplasty in 20 patients with symptomatic high grade stenosis of MCA, who had either recurrent transient ischemic attacks (TIAs) resistant to medical therapy or perfusion problems. After stenting, the patients was administrated with antiplatelet drug and followed up with DSA、TCD and SPECT. Results Stent placement and angioplasty were successfully performed in all patients except one with MCA rupture during the procedure. The mean degree of stenosis reduced from (78.3?4.7)% to (15.6?4.4)%, and the degree of residual stenosis were less than 30%. None of these patients developed TIAs or stroke during the follow up period. Angiography revealed no evidence of restenosis. TCD and SPECT suggested significant improvement of cerebral perfusion. Conclusions Endovascular stenting for MCA stenosis seems to be a safe and effective therapeutic method. Further study is needed for long term outcome.
2.Effect of endovascular primary stent-assisted angioplasty on atherosclerotic intracranial stenosis
Qinghai HUANG ; Jianmin LIU ; Bo HONG
Journal of Interventional Radiology 1994;0(03):-
Objective To analyse the preliminary outcome and its relevant factors of endovascular stent assisted angioplasty for intracranial stenosis. Methods Sixty one atherosclerotic intracranial stenoses in 57 patients (23 stenoses in posterior and 38 in anterior circulation) were treated with endovascular angioplasty using balloon expandable coronary stents. Results Technical success was achieved in all patients, with no procedural and associated complications except one of intracranial hemorrhage. Angiographic results immediately after stenting suggested that the residual postprocedure stenosis was 0%~32% (mean 8.7%?4.4%), with significant reduction from preprocedure stenosis (74.5%?6.7%). The patients were clinically asymptomatic and had no recurrent TIA and stroke. Follow up angiogram in 43 patients revealed no restenosis (
3.Expression of FOXM1 transcription factor and its clinical significance in cervical cancer
Bo LIU ; Shifeng HUANG ; Hong YUAN
Chongqing Medicine 2014;(24):3143-3145,3148
Objective To detect the expression of FOXM 1 transcription factor in cervical cancer tissues and to evaluate its clini-cal significance .Methods Immunohistochemical staining was employed to detect the expression of both FOXM 1 and Ki-67 in a va-riety of cervical tissues respectively from 38 patients with cervical cancer ,22 with cervical intraepithelial neoplasia (ranging from CINⅠ to CIN Ⅲ) and 17 with normal cervical epithelium .Results Abnormal expression rate of FOXM 1 was respectively 5 .88% , 63 .6% and 92 .1% in normal cervix ,CIN and cervical cancer ;Deregulated FOXM1 expression in cervical cancer tissues was signifi-cantly correlated with patients’ pathological differentiation ,clinical stage ,post-operational recurrence and Ki-67 expression level . Conclusion FOXM1 expression may be correlated with the deregulated proliferation ,malignant progression ,staging and prognosis in cervical cancer .
4.Analysis of hyponatremia incidence in patients with ruptured intracranial aneurysms
Tao XIN ; Jianmin LIU ; Yi XU ; Bo HONG ; Qingha HUANG
Academic Journal of Second Military Medical University 1982;0(01):-
Objective: To investigate the hyponatremia incidence in patients with ruptured intracranial aneurysms and the correlation with Fisher grading and cerebral vasospasm. Methods: Totally 150 patients with ruptured intracranial aneurysms from March 1998 to May 2001 were divided into anterior communicating artery (ACoA) group,posterior communicating artery (PCoA) group and middle carotid artery(MCA) group according to the sites of aneurysms.The patients were treated with GDCs interventionally and the incidences of hyponatremia were analyzed. Results: The incidences of hyponatremia in 3 groups were 48%(32/67),15%(8/52) and 16%(5/31),respectively; The incidences of severe hyponatremia of 3 groups were 30%(20/67),6%(3/52) and 6%(2/31), respectively. In ACoA group, the incidences of hyponatremia in Fisher grade Ⅲ-Ⅳ and Ⅰ-Ⅱ were 67%(20/30) and 32%(12/37) and the incidences with and without vasospasm were 71%(24/34) and 24%(8/33), respectively. Conclusion: The ACoA group has a significantly higher incidence of common and severe hyponatremia than the other groups. In ACoA group,hyponatremia is significantly more often in Fisher grade Ⅲ-Ⅳ cases and those with vasospasm.
5.Teaching reform of diagnostics based on clinical skill competition
Bo HUANG ; Yuanfang DUAN ; Hong MEI ; Jianping XIE
Chinese Journal of Medical Education Research 2017;16(4):346-350
In view of the current situation of the teaching of diagnostics, this paper analyzes the ex-isting problems and deficiencies , and puts forward the teaching reform of the National Medical College Students' clinical skills competition. Through the construction of experimental teaching demonstration center of clinical skills, we set up theclinical skills associationamong the students, boldly try innovative training, strengthen humanistic education and take other measures to improve the quality of clinical practice teaching of diagnostics, so as to achieve the purpose of the competition focusing on promote teaching, learning and using by competition.
6.Effects of Using Topiramate Combined with Traditional Chinese Herbal Medicine to Treat Tourette's Syndrome in Children
xiao-hong, QI ; xiao-bo, HUANG ; li-li, TIAN
Journal of Applied Clinical Pediatrics 2006;0(15):-
0.05].After 12 week treatment,the YGTSS total score in study group was significantly lower [(27.88?14.24) vs(36.53?17.45) scores] and the reduction rate of YGTSS score was significantly higher [(43.12?18.42)% vs(33.49?14.38)%] compared with those in control group(Pa
7.Relationship between contrast-enhanced ultrasound of renal cortical blood perfusion and SCr, BUN in rabbits with acute renal failure
Zhi JIANG ; Xiaoling HUANG ; Hong YANG ; Bo TU ; Liping LIU
Chinese Journal of Medical Imaging Technology 2010;26(4):597-600
Objective To evaluate the renal cortical blood perfusion changes in rabbits with acute renal failure (ARF) with gray scale contrast-enhanced ultrasound, and to explore the relationship between these changes and the blood creatinine (SCr), as well as the blood urea nitrogen (BUN). Methods Rabbit ARF models were established with 50% glycerin injected into the rabbits' thighs. Gray scale contrast-enhanced ultrasound was performed on the day before injection (T_0) and 1, 4, 8, 12 days (T_1, T_4, T_8, T_(12)) after injection. The renal cortex perfusion time-intensity curve (TIC) was analyzed, including parameters like arrival time (AT), time to peak intensity (TTP), amplitude of peak intensity (A) and slope rate of TIC (β) of renal cortex. Meanwhile the SCr and BUN were measured, the correlation between SCr, BUN and parameters were analyzed. Results Compared with the value of T_0, the value of TTP, A, β after injection (T_1, T_4, T_8) were statistically different, respectively (P<0.05), but the differences among T_1, T_4 and T_8 were various. No linear correlation between above parameters and SCr, BUN was found. Conclusion The renal cortical blood perfusion changes can be early observed with gray scale contrast-enhanced ultrasound, but there is no linear correlation between the changes of parameters and SCr, BUN.
8.Pulsed radio-frequency stimulation combined with nerve block for cervicogenic headache
Bo LI ; Hui CHU ; Hong HUANG ; Hang YU ; Zhijiu XU
Chinese Journal of Physical Medicine and Rehabilitation 2012;(11):837-840
Objective To observe the clinical effect on cervicogenic headache (CEH) of pulsed radiofrequency stimulation (PRF) applied to the C2 dorsal root ganglion combined with nerve block.Methods A total of 78 cases diagnosed as CEH were randomly divided into a combined treatment group,a PRF treatment group and a nerve block group.The combined treatment group was given both PRF applied to the C2 dorsal root ganglion and blocking therapy.The other two groups were given only one treatment or the other.All the treatments were once weekly for 3 weeks.Before treatment and 1,3 and 6 months after treatment,all of the patients' headaches were evaluated using a visual analogue scale (VAS).Results At 1,3 and 6 months after treatment,the average VAS scores of all three groups had decreased significantly.The VAS ratings dropped the most in the combined treatment group,followed by the PRF group and then the nerve block group.All the intergroup differences were statistically significant.The combined treatment group's cure rate (88%) was significantly better than that of the PRF group (81%),which was significantly better than that of the nerve block group (54%).Conclusion Combining PRF applied to the C2dorsal root ganglion with nerve block therapy has a synergistic effect on CEH.The curative effect of the combined treatment was better than either PRF or blocking alone.
9.Report of a case of sphenoid sinus meningoencephaloceles misdiagnosed as cysts.
Yan-hong XU ; Ding-qing HUANG ; Hai-bo YANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(5):430-430
Diagnostic Errors
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Encephalocele
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diagnosis
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Female
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Humans
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Meningocele
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diagnosis
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Middle Aged
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Mucocele
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diagnosis
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Sphenoid Sinus
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pathology
10.Combined scleral buckle and vitrectomy as a primary surgery for pseudophakic and aphakic retinal detachments
Bo, QIN ; Li-Na, HUANG ; Tie-Ying, ZHAO ; Hong-Bo, CHENG
International Eye Science 2007;7(6):1520-1521
·AIM: To determine whether a combined scleral buckle and pars plana vitrectomy, as a primary surgery, owns any advantage over a single scleral buckling in pseudophakic and aphakic retinal detachments.·METHODS: Thirty consecutive pseudophakic/aphakic retinal deachments were included in this retrospective study. Each patient underwent combined scleral buckle and pars plana vitrectomy, and was followed up for 3 to 14 months. Patients were examined with respect to anatomic reattachment, visual acuity improvement, and surgical complications.·RESULTS: All eyes were anatomically reattached after the first operation. All patients had an increase in their visual acuity, and there were no complications attributable to the vitrectomy procedure.·CONCLUSION: A combined surgery for primary pseudophakic/aphakic retinal detachments offers significant benefits to scleral buckling alone. The improved uccess rate is contributing to the function of vitrectomy, which improves peripheral visibility and reduces the occurrence of proliferative vitreoretinopathy (PVR).