Ceramics ; Esthetics, Dental ; Humans

Atherosclerosis ; prevention & control ; Humans ; Vaccination

Finite element analysis can be used to study the change of the structure and the interior field intensity of human and animal body organs and tissues with simulation experiment. We in our research used finite element analysis software to analyze and solve the spinal cord surface potential problems, and investigated the transmission features of signals generated by interneurons in spinal nerves which were related with body motion control and sensory processing. A three dimensional model of electrical source in rat spinal cord was built, and the influence on potential distribution on spinal cord surface caused by position changes of electrical source in transverse direction and dorsoventral direction were analyzed and calculated. We obtained the potential distribution curves of spinal cord surface and found that the potential distribution on spinal cord surface showed monotone. In addition, potentials of some registration points were smaller than that of registration points around.
Action Potentials ; Animals ; Computer Simulation ; Finite Element Analysis ; Humans ; Interneurons ; physiology ; Models, Anatomic ; Rats ; Spinal Cord ; physiology

Acupuncture Analgesia ; Animals ; Central Nervous System ; metabolism ; Electroacupuncture ; Nitric Oxide ; metabolism ; Pain Threshold ; physiology ; Rats ; Rats, Wistar

ObjectiveTo evaluate the safety and efficacy o f microvascular deco mpression in the management of primary trigeminal neuralgia.Methods We review ed 13 patients with unilateral primary trigeminal neuralgia treated by microvasc ular decompression. Conventional spin-echo (SE) sequence and 3-D fast inflow wit h steady-state precession (3-D-FISP) sequence MRI scans were used preoperatively to find evidence of neurovascular compression. The operation was accessed by re trosigmoidal approach and the nerve root was separated away from pressure vessel s by artificial vascular patch.ResultsDuring operations it w as found that tr igeminal nerves were pressed on by blood vessels in all the cases (by the superi or cerebellar artery in 11 cases; by the basilar artery and the superior cerebel lar artery in 1 case; and by the vein in 1 case). Complete pain relief was achie ved in all the patients without mortality or permanent complications. Eleven pat ients were clinically followed for 6～24 months with a mean of 13 months, and no recurrence was seen. ConclusionsMicrovascular decompression is a safe and effective procedure in the treatment of primary trigeminal neuralgia.

ObjectiveTo probe the short-term efficacy of endovascu lar stent-as sisted angioplasty for basilar artery stenosis.MethodsTwenty p atients with s ymptomatic basilar artery stenosis were treated by angioplasty using a balloon-e xpandable coronary stent.ResultsThe basilar artery caliber r eturned to norma l size in 12 cases and restored by more than 80% in the remaining 8 cases. No tr ansient ischemic attack (TIA), stroke, or other peri-operative complications rec urred. Follow-up angiography in 13 patients revealed no re-stenosis.Co nclusionsShort-term efficacy of endovascular stenting for basilar arte ry stenosis is promising.

ObjectiveTo assess the value of stent-assisted angiopl asty in the treatment of extracranial carotid stenosis.Methods A total o f 164 cases of ex tracranial carotid stenosis from October 2000 to December 2002, including 146 ca ses of carotid bifurcation stenosis, 13 cases of extracranial internal carotid s tenosis, and 5 cases of common carotid stenosis, were treated by self-expandable stent placement and angioplasty.ResultsStent placement and angioplasty was successfully accomplished in all the 164 patients. The degree of stenosis was re duced from (78 8?13 6)% before the treatment to (10 2?7 5)% after the oper atio n. There were 1 case of transient ischemic attack (TIA) (0 6%) and 1 case of mi n or stroke (0 6%) during the peri-operative period, but no death or major stroke took place. Follow-up for 3～30 months (mean, 8 9 months) in 145 cases found no T IA, cerebral apoplexy or death. Forty-five patients were followed by digital sub traction angiography (DSA) 6 months after the treatment, and asymptomatic re-ste nosis occurred in 1 case (2 2%).ConclusionsEndovascular ste nt-assisted angio plasty for extracranial stenosis is safe and effective, with favorable short-ter m outcomes.

Objective Endovascular stenting or combined stenting and Guglielmi detachable coils packing for the treatment of intracranial fusiform and wide necked aneurysms were reported to access the feasibility of the procedures.Methods The coronary stents were implanted across the neck of 3 vertebral fusiform aneurysms and 6 wide necked aneurysms. Microcatheters were introduced into the aneurysm sacs through stent mesh, and finally GDCs were used to embolize the aneurysms. Results The stents were precisely deployed resulting in total occlusion of 7 cases with more than 90% occlusion in 2 cases. All patients recovered well with patency of the parent arteries.Conclusions Endovascular therapy with combined stent implantation and microcoil placement maybe a valid alteration for the treatment of intracranial fusiform or wide necked aneurysms.

Objective To analyze the causes, prevention and treatment of repture druing procedure for intracranial aneurysm embolization with GDC.Methods All the seven patients were embolized. Six patients were ruptured during the procedure and continuously embolized until the bleeding was halted. Another one was identified by post procedure CT. Results Four patients recovered unevent fully with one only suffering from mild deficit. Another 2 patients died of hyper intracranial pressure within one week. Conclusions Rupture during procedure of intracranial aneurysm embolization with GDC may be related to manipulation, properties of the parent artery and arneurysm. Continuous embolization with GDC will provide favorable prognosis for the patients.

Objective To evaluate the endovascular embolization treatment of large and giant ophthalmic aneurysms. Methods Three aneurysms were embolized with coils only and 5 aneurysms were treated with stent placement togather with subsequent coiling. Results In the 3 aneurysms treated only with GDC, total embolization was achieved in 1 and partial embolization in 2. In the stent placement and coiling case, 4 aneurysms were densely packed and another one was partially packed. Conclusions Combined stenting and coiling is effective and safe for the treatment of large and giant ophthalmic artery aneurysm with the preservation of parent artery.