1.Awareness of Colorectal Cancer among the Urban Population in the Klang Valley
Cimmeran Kaur Sindhu ; Anisha Kaur Nijar ; Leong Pooi Yee ; Li Zi Qi ; Hong Chia Yin ; Lalitha Malar ; Ping Yein Lee ; Kwa Siew Kim
Malaysian Family Physician 2019;14(3):18-27
Background: Colorectal cancer (CRC) is the second most common cancer in Malaysia. Awareness of
risk factors, symptoms and warning signs of CRC will help in early detection. This paper presents the
level of CRC awareness among the urban population in Malaysia.
Method: A cross-sectional study was conducted from November 2015 till December 2016 at three
government clinics in the Klang Valley. The validated Bowel Cancer Awareness Measure questionnaire
in both English and Malay was used. The mean knowledge scores for the warning signs and risk factors
of CRC in different socio-demographic groups were compared using ANOVA in SPSS version 23.
Statistical significance was set at p<0.05 and a 95% confidence level.
Results: Of the 426 respondents, 29.1% were unable to recall the warning signs and symptoms of
CRC. Average recall was less than two warning signs and symptoms (mean 1.62, SD 1.33). The mean
total knowledge score for CRC was 9.91 (SD 4.78), with a mean knowledge scores for warning signs
and risk factors at 5.27 (SD 2.74) and 4.64 (SD 2.78), respectively. Respondents with a higher level
of education were found to have higher level of knowledge regarding the warning signs of CRC. There
was a significant positive association between knowledge score for warning signs and level of confidence
in detecting warning signs. Regarding the total knowledge score for CRC, 3.3% of respondents scored
zero. For warning signs and risk factors, 8.2% and 8.5% of respondents had zero knowledge scores,
respectively.
Conclusions: Generally, awareness of CRC is poor among the urban population of Klang Valley.
Greater education and more confidence in detecting warning signs are significantly associated with
better knowledge of warning signs. CRC awareness programs should be increased to improve awareness.
2. The effects of glycyrrhizic acid and glabridin in the regulation of CXCL5 inflammation gene on acceleration of wound healing
Hong Yung YIP ; Melissa Su Wei POH ; Yoke Yin CHIA
Asian Pacific Journal of Tropical Biomedicine 2016;6(2):108-113
Objective: To evaluate the anti-inflammatory property of both glycyrrhizic acid (GA) and glabridin in reducing inflammation to accelerate wound regeneration on 3T3-L1 and NIH-3T3 fibroblast cell lines. Methods: Cell proliferation and viability assay (MTT assay), scratch wound healing assays, and quantitative real-time PCR were conducted to investigate the effects on cell proliferation, cell migration, and expression of CXC chemokine ligand 5 inflammation gene respectively. Results: Results showed that at a low concentration of 1 × 10
3.Catheter Removal Planning Based on Phased Evaluation for Severe Traumatic Brain Injury: A Case Report
Ping CHEN ; Zheng YIN ; Zhi-jie HE ; Chin-hsuan CHIA ; Jie JIA ; Yi WU ; Hong JIANG
Chinese Journal of Rehabilitation Theory and Practice 2021;27(7):864-868
Objective:To introduce a phased evaluation for severe traumatic brain injury in clinical nursing, to promote catheter removal planning. Methods:A case of severe traumatic brain injury in our hospital in October, 2018 was reviewed. Results:This case accepted a phased evaluation about consciousness, condition of tracheotomy and extubation, bladder safety capacity and residual urine volume, and the rehabilitation nursing targeted to the results. After 54 days of treatment and care, all the catheters were removed in a planned way. Conclusion:The phased evaluation for severe traumatic brain injury may promote the planning of catheter removal, prevent repeated tube placement, and facilitate the recovery of patients.