A prospective study was carried out on 75 patients in which there were 54 Silic-silicosis patients (BBP- Si) to investigate the change of lung artery pressure in the patients with silicosis. The participants were divided into 2 groups: control group included 21 patients who had no cardiological or respiratory diseases; BBP-Si group included 54 patients. Results: the incidence rate of p type was high: 44 cases (81.5%), q type had 8 cases (14.8%). Injuries of level 1 had the highest rate (62.9%). In the BBP-Si group, the mean value of systolic lung artery pressure and the mean value of lung artery pressure were higher than that of control group with p<0.001 and p<0.05, respectively. The mean value of diastolic lung artery pressure did not change. Systolic and average lung artery pressure increased high in the group of mass fibrosis.
Silicosis ; Pulmonary Artery

In this study, PCR technique was used with 2 primer pairs for amplifying DNA fragments at 5’ and 3’ of the gene encoding diphteria toxine of the strains Corynebacterium diphtheriae. After the cloning and sequencing, 2 separated fragments were joined to form a complete gene. The sequence of gene was translated into protein and the results were submitted into Gene Bank Database
Diphtheria Toxin ; Genes ; Corynebacterium diphtheriae

Study on 75 subjects included 54 silicatosis patients (51 males, 3 females, mean age 43.9±9.8) working in seagoing vessel repairing and new building branch. Control group included 21 people (19 males, 2 females). All of these subjects were working in a labor environment, in which SiO2 dust level exceeded allowable limit from 4 to 21 folds with mean exposed times 16.8±5.2 years. The results showed that: 54 silicatosis patients had remarkable symptoms such as chest pain (83.3%), exercise dyspnea (74.1%), decreased alveolus soughing (59.3%). There were 75.9% in all of patients had pulmonary ventilation disorder, in which mainly were limited pulmonary ventilation disorder (53.7%).
Pulmonary Ventilation ; Patients ; Environment

291 healthy youths with ages of 17-30, without internal disease and osteoarthropathy and congenital osteoarthological defects were monitored the age, gender, height, weight of vertebrae in the lumbar and lumbosacral region. The results showed that the rate of vertebral double spine was significant higher than this of other defects. The wide of vertebrae was increasingly from L1 to L5 (average of 4.5+/-0.5cm). The height of vertebrae was 3.1+/-0.3cm. The average thickness of intervertebral disks was 1.3+/-0.3cm. The average concavity index was 2.2+/-0.3mm. Flat-flat angle in the lumbosacral spine was 17.1+/-3.9o. The open angle in the lumbar spine was 31+/-7.4o
Lumbar Vertebrae ; radiography ; diagnosis

Objective To investigate the effect of Smecta on II pressure ulcers in elderly patients.Methods Fifty-two elderly patients with skin pressure ulcers hospitalized in our hospital during February 2011 and September 2012 were randomly divided into experimental group(n=26),in which Smecta was applied on the pressure ulcers,and control group(n=26),in which ulcers powders were applied on the ulcers.The two groups were compared concerning the curative effects.Results The curative effect in the experimental group was significantly better than that of the control group(P<0.05)and the time for ulcers healing in the former group was significantly shorter than that of the control(P<0.05).Conclusions Smecta is more effective in the treatment of pressure ulcers in elderly patients with II pressure ulcers.It is simple in clinical use and cheap in cost,which should be encouraged for wider use.

Anti-Infective Agents ; therapeutic use ; Bacterial Infections ; drug therapy ; Child ; Humans

Background Nha Trang Institute of Vaccines Medical Biologicals has produced successfully vaccine for human influenza A/H5N1 in embryonic chicken eggs. Effectiveness of the vaccine immune response is highly dependent on the type of adjuvant used.\r\n', u'Objective: To study adjuvants for preparing A/H5N1 influenza vaccine.\r\n', u'Subjects and methods: The study used a comparative approach on capacity to increase the immune response of various adjuvants AIPO4, Chitosan and Freund tested in mice. Experiment of erythrocyte agglutination reaction is used to measure levels of antibody response in mice blood. The process of weight gain in mice after injection of vaccine adjuvant mixture is monitored.\r\n', u'Results: HA antibody level of the vaccine adjuvant mixture is higher than of the vaccine without adjuvant. Capacity of stimulating immune response of Chitosan adjuvant is higher than AlPO4. Repeat injection on day 20th is suitable for vaccine with AlPO4or vaccine without adjuvant. Repeat injection is after day 20th for vaccine with Chitosan or Freund depending on the amount of residual antibody in the blood. \r\n', u'Capacity of stimulating immune response of Freund adjuvant is the best in the 3 adjuvants but the safety of this adjuvant is low\r\n', u' Freund adjuvant should be used only for animals. When using Freund adjuvant to induce immunity to animals it should determine the amount of antibodies causing immune before repeating.\r\n', u'Conclusion: Freund adjuvant should be used only for animals. \r\n', u'\r\n', u'
Influenza A Virus ; H5N1 Subtype

Background: Sa Pa is one of the mountain communes with a temperate climate that is appropriate for the growing of traditional medicinal herbs. Objectives: To investigate the experiences of using traditional remedies of the H\u2019mong ethnic minority in Sa Pa commune, Sa Pa district, Lao Cai province. Subjects and method: The cross-sectional study had enrolled 28 traditional herbal practitioners, 23 commune officers and 289 family\u2019s representatives who had experiences in traditional herb usage. Results: 72 traditional remedies were collected. In which, 58.33% of remedies had 1 medicinal component, 13.89% of remedies had 2 medicinal components. 158 common herbal medicines used for primary health care were collected. In which, the herbs belonged to Asteraceae family accounted for the highest rate: 11 species (7.4%); followed by the Lamiaceae family: 8 species (5.4%); Rosaceae, Zingilbeaceae and Convallariaceae family: 5 species (3.4%); then the Acanthaceae, Araceae, Poaceae and Ranunculaceae family: 4 species (2.7%). Decoction was the most recurrent use (68.99%), followed by poultice on the skin (10.13%), ingesting the herbs (7.6%) and others (<10%). Conclusion: The traditional medicinal herbs of the H\u2019mong ethnic minority at Sa Pa commune, Sa Pa district, Lao Cai province were multiform and were used in different ways.
traditional medicinal herbs ; H\u2019mong ethnic minority

Background: The communities and social organizations of many nations on the world participated actively in primary health care. According to World Health Organization, 80% of people in the developing countries have needs of primary health care by traditional medicines now. Thus investigation about systemic herbal medicines, remedies of compatriots of various Vietnamese ethnic origins in general, of H\u2019Mong peoples at Sa Pa commune, Sa Pa district, Lao Cai province in particular, is necessary. Objective: To investigate the medicinal plants of the \u201dH\u2019Mong peoples\u201d used for primary health care at the Sa Pa commune, Sa Pa district, Lao Cai province. Subjects: The study includes 28 traditional herbal doctors, 23 commune officers and 289 representatives of families. Method: This was a cross study. Results: The authors collected 158 herbal medicines used for primary health care. Among them, the Asteraceae there were 11 species (7.4%), the Lamiaceae there were 8 species (5.4%). The Rosaceae, Zingilbeaceae, Convallariaceae there were 5 species (3.4%). Herbal medicine groups had 4 species (2.7%) that included the Acanthaceae, Araceae, Poaceae and Ranunculaceae. The used components were all of tree (31.65%), tree root, tuberous root (25.32% and sheets (22.42%). Conclusion: The herbal medicines that the \u201dH\u2019Mong peoples\u201d used for primary health care at Sa Pa commune, Sa Pa district, Lao Cai province had a valuable and plentiful source which needs to be develop and use effectively.
Traditional medicine ; herbal ; primary health care

Birth defects are the abnormalities in structure,function or metabolism of embryonic or fetal development.They are the main cause of early abortion,stillbirth,perinatal mortality,infant mortality and congenital disabilities.Birth defects affect not only the health and life quality of children,but also the population quality of the whole country.This paper reviews the current epidemic situation and possible causes and risk factors of birth defects.It also expounds on the importance of epidemiological study on birth defects,possibility of primary prevention of birth defects,and necessity of interdisciplinary and collaborative research.It may provide reference for prevention and control of birth defects.