1.A PROPOSAL OF A SIMPLE COMBINATION TEST FOR RELATIVE LOCAL ENDURANCE FOR GENERAL POPULATION
AKIHISA HASEBE ; SETSUKO TERADA ; HIDEAKI MATSUKI ; FUMIO OSAKA ; HITOSHI KASUGA ; HITOSHI YUNOKI ; YOSHIO ISHIBASHI
Japanese Journal of Physical Fitness and Sports Medicine 1976;25(4):183-195
We have tried to design a method to measure health degrees as one of ideas to grasp the activity of general population.
We should like to suggest to measure relative local endurance and to observe its index or their mutual index ratio measurement of their endurance in each item.
Exercise method was already reported in the report (1) .
Loading time by standing arm test (SAT) is 1 minute, knee test (KT) is 30 seconds, sit up test (ST) is 30 seconds for general population.
Extimate formulas on index are given as follows,
SAT=120-2Y/ (P1+P2) ×4×1.36×100=2206-37Y/P1+P2
KT=120-2X/ (P1+P2) ×4×1.22×100=2459-41X/P1+P2
_??_ST30=120-3Z/ (P1+P2) ×4×1.20×100=2500-63Z/P1+P2
_??_ST30=120-3Z/ (P1+P2) ×4×1.38×100=2174-63Z/P1+P2
X, Y and Z show frequency of impossible in each exercise.
The above index itself can be compared with index in another person, but for the individual SAT/KT and ST/KT show that balance of moving and in case need SAT+ KT and SAT+KT+ST can be compared as the whole body endurance.
After this, we are expected to investigate whether the health degree in each individual can be observated or not, by these methods.
2.A Pharmacoepidemiologic Study on the Relationship between Neuropsychiatric Symptoms and Therapeutic Drugs after Influenza Infection
Toshiharu Fujita ; Yosuke Fujii ; Yoshihiro Watanabe ; Hitoshi Osaka ; Takahito Wada ; Masaaki Mori ; Shumpei Yokota
Japanese Journal of Pharmacoepidemiology 2010;15(2):73-95
Objective: The mechanism underlying the development of neuropsychiatric symptoms such as unconsciousness, abnormal behavior, delirium, hallucinations, and convulsions in influenza has not been thoroughly investigated. The relationship between drug administration and neuropsychiatric symptoms during influenza is also poorly understood. This study is the first pharmacoepidemiologic study focused on investigating the relationship between drug administration and neuropsychiatric symptoms.
Design: Cohort study
Methods: Study subjects were patients under 18 years old who had influenza during the 2006/07 season. We prepared two kinds of questionnaires for doctor and for patient's family, and carried out the survey between January and March, 2007. Using data from 9,389 patients, we analyzed the relationship between neuropsychiatric symptoms, such as delirium, unconsciousness and convulsion, and drug administration of acetaminophen and oseltamivir.
Results: Analysis of the relationship between delirium and drug administration provided hazard ratios of 1.55(p=0.061)for acetaminophen and 1.51(p=0.084)for oseltamivir. These hazard ratios, which were adjusted for risk factors by multivariate analysis of the proportional hazard model, showed an increasing tendency of delirium after administration of each drug. In patients who received oseltamivir, a high incidence of delirium was observed between 6 and 12 hours after onset of fever. Furthermore, delirium was found to develop in a shorter time following oseltamivir use than it did after acetaminophen use. There was no relationship between unconsciousness and acetaminophen administration, as demonstrated by a hazard ratio of 1.06(p=0.839). The incidence of unconsciousness increased significantly with oseltamivir use with a hazard ratio of 1.79(p=0.0389), and unconsciousness was found to occur in a short time after oseltamivir use.
Conclusion: The results obtained from this study suggest that there are increased risks of delirium and unconsciousness with drug administration. Further pharmacoepidemiologic studies for hypothesis testing are required to study the relationship between abnormal behavior and drug administration.
3.Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats.
Hiroshi HANAMOTO ; Hitoshi NIWA ; Mitsutaka SUGIMURA ; Yoshinari MORIMOTO
International Journal of Oral Science 2012;4(1):24-29
Stimulation of the trigeminal nerve can elicit various cardiovascular and autonomic responses; however, the effects of anesthesia with pentobarbital sodium on these responses are unclear. Pentobarbital sodium was infused intravenously at a nominal rate and the lingual nerve was electrically stimulated at each infusion rate. Increases in systolic blood pressure (SBP) and heart rate (HR) were evoked by lingual nerve stimulation at an infusion rate between 5 and 7 mg·kg(-1)·h(-1). This response was associated with an increase in the low-frequency band of SBP variability (SBP-LF). As the infusion rate increased to 10 mg·kg(-1)·h(-1) or more, decreases in SBP and HR were observed. This response was associated with the reduction of SBP-LF. In conclusion, lingual nerve stimulation has both sympathomimetic and sympathoinhibitory effects, depending on the depth of pentobarbital anesthesia. The reaction pattern seems to be closely related to the autonomic balance produced by pentobarbital anesthesia.
Adjuvants, Anesthesia
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administration & dosage
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pharmacology
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Adrenergic alpha-Antagonists
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pharmacology
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Animals
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Autonomic Nervous System
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drug effects
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Cats
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Dose-Response Relationship, Drug
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Electric Stimulation
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Electrocardiography
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drug effects
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Hemodynamics
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drug effects
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Hexamethonium
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pharmacology
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Hypnotics and Sedatives
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administration & dosage
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pharmacology
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Infusions, Intravenous
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Lingual Nerve
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drug effects
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physiology
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Male
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Neural Inhibition
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Phentolamine
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pharmacology
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Trigeminal Nerve
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drug effects
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physiology
5.STUDY OF OBESITY INDEXES
AKIHISA HASEBE ; SETSUKO TERADA ; HIDEAKI MATSUKI ; FUMIO OSAKA ; HITOSHI KASUGA ; TERUYO FUKUDA ; HIROMICHI YOKOYAMA ; TOSHIO SAKAMAKI ; HITOSHI YUNOKI ; TOSHIMITSU KUWAJIMA ; KENJI KODA ; TOSHIHIKO KATO ; SHIN HORIE
Japanese Journal of Physical Fitness and Sports Medicine 1978;27(2):81-85
As regards obesity screening tests, it's a widly known fact that there are many problems in the existing notation of various body indices.
Moreover, in regards to the determination of skin-fold thickness, measurments must be taken at two or three places, and this, plus the fact that a certain amount of expertise is necessary, represent a shortcoming.
Using abdominal girth, which can be relatively easily measured, together with the chest girth measurment, the author examined a method for assessing obesity.
Various body indices were computed from height, weight, chest measurement, abdominal girth, etc. and the correlation between their value and skin fold thickness and average skin fold thickness was determined.
As a result of this, abdominal girth measurement and evaluation may be used in obesity screen tests in the following way.
1. Method for measuring abdominal girth.
[1] Have the patient assume normal posture.
[2] Girth is measured (in centimeters) around the area mid way above the navel while the patient resting expiratory state with arms hanging limp and shoulders relaxed.
2. Method for computing obesity index.
obesity index=height (in cm) ×10/abdominal girth (in cm)
The subject of the above research is extreamly limited in respect to age range. Therefore, the authors would like to examine further to see if this method is applicable to all age renges.
7.Preoperative flexion contracture is a predisposing factor for cartilage degeneration at the patellofemoral joint after open wedge high tibial osteotomy
Shuhei OTSUKI ; Kuniaki IKEDA ; Hitoshi WAKAMA ; Nobuhiro OKUNO ; Yoshinori OKAMOTO ; Tomohiro OKAYOSHI ; Yuki MIYAMOTO ; Masashi NEO
The Journal of Korean Knee Society 2020;32(4):e55-
Purpose:
The purpose of the study was to determine the effect of cartilage degeneration at the patellofemoral joint on clinical outcomes after open wedge high tibial osteotomy and to investigate the predisposing factors for progressive patellofemoral cartilage degeneration.
Methods:
Seventy-two knees were evaluated on second-look arthroscopy in patients who opted for plate and screw removal at an average of 20.1 months after osteotomy. Cartilage degeneration at the patellofemoral joint was evaluated using the International Cartilage Repair Society grading system, with cases divided into progression and nonprogression groups. Radiographic parameters of the patellofemoral anatomy, knee range of motion, and clinical outcomes were evaluated from the preoperative baseline to the final follow up, on average 50 months after osteotomy. A contracture > 5° was considered a flexion contracture.
Results:
Cartilage degeneration progressed in 31 knees, and preoperative knee flexion contracture was significantly associated with progressive degeneration (P < 0.01). The Lysholm and Kujala scores were significantly lower in the progression group (87.9 and 85.3, respectively) than in the nonprogression group (91.6 and 93.6, respectively) (P < 0.05). The odds ratio of the flexion contracture resulting in progression of patellofemoral cartilage degeneration was 4.63 (95% confidence interval, 1.77–12.1). No association was detected between progressive degeneration and age, sex, body mass index, Kellgren-Lawrence grade, or radiographic parameters.
Conclusions
Flexion contracture may be associated with progression of cartilage degeneration at the patellofemoral joint and may negatively affect the clinical outcomes after open wedge, high tibial osteotomy.
8.Preoperative flexion contracture is a predisposing factor for cartilage degeneration at the patellofemoral joint after open wedge high tibial osteotomy
Shuhei OTSUKI ; Kuniaki IKEDA ; Hitoshi WAKAMA ; Nobuhiro OKUNO ; Yoshinori OKAMOTO ; Tomohiro OKAYOSHI ; Yuki MIYAMOTO ; Masashi NEO
The Journal of Korean Knee Society 2020;32(4):e55-
Purpose:
The purpose of the study was to determine the effect of cartilage degeneration at the patellofemoral joint on clinical outcomes after open wedge high tibial osteotomy and to investigate the predisposing factors for progressive patellofemoral cartilage degeneration.
Methods:
Seventy-two knees were evaluated on second-look arthroscopy in patients who opted for plate and screw removal at an average of 20.1 months after osteotomy. Cartilage degeneration at the patellofemoral joint was evaluated using the International Cartilage Repair Society grading system, with cases divided into progression and nonprogression groups. Radiographic parameters of the patellofemoral anatomy, knee range of motion, and clinical outcomes were evaluated from the preoperative baseline to the final follow up, on average 50 months after osteotomy. A contracture > 5° was considered a flexion contracture.
Results:
Cartilage degeneration progressed in 31 knees, and preoperative knee flexion contracture was significantly associated with progressive degeneration (P < 0.01). The Lysholm and Kujala scores were significantly lower in the progression group (87.9 and 85.3, respectively) than in the nonprogression group (91.6 and 93.6, respectively) (P < 0.05). The odds ratio of the flexion contracture resulting in progression of patellofemoral cartilage degeneration was 4.63 (95% confidence interval, 1.77–12.1). No association was detected between progressive degeneration and age, sex, body mass index, Kellgren-Lawrence grade, or radiographic parameters.
Conclusions
Flexion contracture may be associated with progression of cartilage degeneration at the patellofemoral joint and may negatively affect the clinical outcomes after open wedge, high tibial osteotomy.
9.The effect of carbohydrate mouth rinse in isometric hand grip performance
Yoko HIRATA ; Tsuyoshi WADAZUMI ; Naomi HAMADA ; Asako SHIRAI ; Hitoshi WATANABE
Japanese Journal of Physical Fitness and Sports Medicine 2021;70(4):269-276
This study aimed to clarify the effects of carbohydrate mouth rinse on exercise performance. We examined the effect of mouth rinse on fatigability. Thirty healthy male college students completed three trials with non mouth rinse (CON), mouth rinse intervention of 6% glucose (GMR), and artificial sweetener (PLA). Handgrip exercise was performed as a fatigue task. The subjects performed a 10-seconds maximal voluntary contraction (MVC) followed by a 40% MVC rhythmic grasping movement for 14 per minutes, followed by a 4-seconds rest. This set of exercises was performed for a total of ten sets. Mouth rinse was performed from the 5th set to the 10th set. The subjects were divided into three groups: L, M, and S, according to the degree of decrease in MVC due to fatigue in CON. The effect was evaluated using the rate of change in MVC after the mouth rinse. The evaluation was performed for each trail and group. In the L group, mouth rinse significantly improved the rate of change of MVC compared with the other trials (GMR vs. CON: P = 0.002; PLA vs. CON: P = 0.042). A significant trend was observed in the M (GMR vs. CON: P = 0.062), but not in the S. In conclusion, the effects of mouth rinse differed depending on fatigability in isometric hand grip performance, with mouth rinse inhibiting the decrease of motor fatigue. In addition, it was suggested that the sweetness of carbohydrates may have an effect on mouth rinse.