Objective To summarize and analyze the clinical experience in the use of ultrasonic scalpel in skeletonized internal using bilateral sketetonized internal mammary artery harvested by ultrasonic scalpel in Juntendo University Hospital.Results The number of distal anastomoses was(4.1±1.5).Major complieations included severe arrhythmia in 2 patients.cerebral infarction complicated with sepsis in 1,diffuse intraveseular coagulopathy complicated with multiple organ failure in 1 patient.and pneumonia in 2 patients.There were 2 patients dead in-hospital.The mean follow-up period Was(15.6±3.2)months.There Was no late death or cardiac-related events during the follow-up periods.Condusion It is simple and safe to skeletonize the internal mammary artery using the ultrasonic scalpel.The early effect of bilateral skeletonized internal mammary artery grafting was satisfactory.