1.A Successful Case of Cardiac Operation and Chemotherapy for Primary Cardiac Malignant Lymphoma with Superior Vena Cava Syndrome
Takao Tsuchida ; Kentaro Yano ; Hitoshi Fukumoto
Japanese Journal of Cardiovascular Surgery 2014;43(3):146-149
Primary cardiac lymphomas are rare cardiac neoplasms with poor prognoses. We report a 61-year-old man who presented with superior vena cava (SVC) syndrome. Trans-thoracic echocardiography showed a 77×91-mm mass occupying the right atrium. The tumor obstructed the SVC. The deteriorating hemodynamics of our patient prompted a surgical intervention. We resected as much of the tumor as possible under cardiopulmonary bypass. The postoperative course was uneventful, and the SVC syndrome disappeared. Pathological examination was consistent with malignant lymphoma, diffuse large B-cell type. After cardiac operation, the patient was treated with rituximab, cyclophosphamaide, adriamycin, vincristin, and prednisone (CHOP-R). The patient has been in good health for 30 months without signs of recurrence.
2.Surgery for Ruptured Abdominal Aortic Aneurysm in Patients over 80 Years Old.
Hitoshi FUKUMOTO ; Takashi NISHIMOTO ; Ken OKAMOTO
Japanese Journal of Cardiovascular Surgery 1993;22(4):356-359
In this study, the author evaluated surgical results in 4 patients over 80 years old (3 males and one female) who were among 24 patients with ruptured abdominal aortic aneurysm (RAAA) who underwent operation at our medical center between November, 1985 and June, 1992. While three patients survived, one, who had preoperative profound shock, died due to mutiple organ failure. The post-operative course of two of the survivors was uneventful, and the other developed non-oliguric renal failure but recovered without hemodialysis. The Fitzgerald classification of the RAAA in the non-survivor was group 4 and that in the 3 survivors was group 2 or 3. The extent of preoperative shock and volume of blood loss were associated with increased operative risk. In conclusion, aggressive resection of RAAA should be performed not only in younger parients but also in elderly patients such as those over eighty years old.
3.Outcome and Problem of Ruptured Abdominal Aortic Aneurysms in Octogenarians
Keiichi Furubayashi ; Masayoshi Nishimoto ; Hitoshi Fukumoto
Japanese Journal of Cardiovascular Surgery 2005;34(1):1-4
Ruptured abdominal aortic aneurysms (RAAA) can be lethal unless appropriate diagnosis and immediate repair are made. Since advanced age is a surgical risk, however, octogenarians are considered as poorer candidates for elective surgical intervention before rupture. The aims of this study were to clarify the problems and factors that are associated with mortality from RAAA in elderly patients. A retrospective study of all infrarenal RAAA patients (n=126) who presented at our center between 1985 and 2003 is presented. The patients were classified into 2 groups, Group O included 37 RAAA patients (male:female=22:15) aged 80 years old or over, and Group Y included 89 RAAA patients (male:female=70:19) under 80 years old. We analyzed and compared preoperative, operative, and postoperative states between groups. The percentage of cardiopulmonary arrests (CPA) was significantly higher in Group O (14/37, 38%) than in Group Y (24/89, 27%). The other preoperative factors (time to reach hospital, time in shock, blood pressure, base excess, hemoglobin, blood urea nitrogen, creatinine, aneurysmal size) were not significantly different between the groups. The operative factors (operation time, aortic clamp time, the amounts of urine output and bleeding during the operation) were not significantly different between the groups. The rates of postoperative complications did not significantly differ between the groups. In a comparison of all cases, including patients with CPA, the survival rate was significantly lower in Group O (14/37, 37.8%) compared with Group Y (55/89, 61.8%). On the other hand, for the patients who underwent prosthetic graft replacement, the survival rate was equivalent in Group O (14/18, 77.8%) and Group Y (55/75, 73.3%). The mortality rate and percentage of CPA in Group O were significantly higher than in Group Y although the preoperative, operative and postoperative statistics are not significantly different. For patients who undergo prosthetic graft replacement, the survival rate is equivalent. These findings suggest that octogenarian patients cannot withstand the hypovolemic shock that is due to RAAA. We recommend elective operation before rupture in elderly patients with AAA.
4.A Patient with an Aberrant Right Subclavian Artery Who Underwent Endovascular Aortic Repair for Stanford Type B Acute Aortic Dissection
Takao Tsuchida ; Masataka Yoshida ; Kentaro Yano ; Hitoshi Fukumoto
Japanese Journal of Cardiovascular Surgery 2016;45(4):205-210
Case : A 75-year-old man was brought to our hospital by ambulance with dorsal pain. Contrast-enhanced computed tomography (CT) revealed acute communicating aortic dissection (Stanford type B) complicated by an aberrant right subclavian artery (ARSCA). Under a diagnosis of type B dissection, conservative treatment by hypotensive therapy and resting was performed. One month after onset, contrast-enhanced CT showed the expansion of the false lumen, and intermittent abdominal pain persisted. To close the entry of the distal arch and reconstruct the ARSCA route, right common carotid artery-right axillary artery bypass, thoracic endovascular aortic repair (TEVAR), and coil embolization of the ARSCA were performed. Five days after surgery, contrast-enhanced CT revealed the expansion of a false abdominal lumen. Abdominal endovascular aortic repair (EVAR) was additionally conducted, leading to the disappearance of false lumen blood flow. ARSCA is a congenital arch vessel abnormality. It may cause obstruction of the esophagus/trachea, aortic aneurysm/dissection of an adjacent area, or aneurysmal changes/rupture of the ARSCA. Various techniques have been reported ; reconstruction of the ARSCA route and closure of the false lumen by de-branch TEVAR may be effective for acute communicating aortic dissection with an ARSCA.
5.A Case of Ruptured Aneurysm Complicating Coarctation of the Aorta. Surgical Aspect Using Percutaneous Cardio Pulmonary Support System.
Takashi NISHIMOTO ; Hitoshi FUKUMOTO ; Eiji TSUJII ; Seiji KINUGASA
Japanese Journal of Cardiovascular Surgery 1993;22(2):123-126
A 22-year-old man was referred to our medical center with an impending rupture of an aneurysm of the descending thoracic aorta. Blood pressure was 180/110mmHg in the right arm but 110/60mmHg in the right foot. The diagnosis was confirmed by chest Xray, enchanced computed tomography and aortogram. Five days later, the chest Xray showed massive effusion in the left pleural cavity. Surgery was immediately performed via a left thoracotomy. Five hundred ml of bloody fluid was found in the pleural cavity but the site of bleeding could not be identified. The aneurysm was 7×10cm in size. Under percutaneous cardio pulmonary support, the aneurysm was replaced by a 22mm Gel-Seal Dacron vascular graft. The intima and the media of the aneurysm were lacerated longitudinally at the region receiving jet flow from isthmus, There was blood coagula between the media and adventitia. During replacement, activated clotting time was maintained at 200∼300sec. As a result, bleeding was limited to 200ml. The postoperative course was uneventful with little difference in pressure between the right arm and right foot.
6.Diagnostic Problems and Outcome of Ruptured Abdominal Aortic Aneurysms with or without Cardio-pulmonary Arrest.
Hitoshi Fukumoto ; Yasuhisa Nishimoto ; Tomohiro Tokumaru ; Akira Fujiwara
Japanese Journal of Cardiovascular Surgery 1997;26(4):207-212
The hospital records of 50 patients treated for ruptured abdominal aortic aneurysms during the past ten years were reviewed. Nine patients in cardio-pulmonary arrest on arrival at our emergency room and 3 resuscitated patients were included in this study. The patients were classified into four groups: the non-shock group (17 cases), shock group (21 cases), post-cardiac resuscitation group (3 cases) and the cardio-pulmonary arrest on arrival (CAPOA) group (9 cases). The mortality rates including preoperative death in each group were 5.9% (non-shock), 57.1% (shock), 66.7% (post resuscitation) and 88.9% (CPAOA). The overall mortality rate was 46%, although the mortality rate in patients receiving graft replacement was 35.6%. The mortality in the non-shock group was significantly lower than in the other three groups. Longer duration of shock, lower preoperative systolic blood pressure level, longer operative time, greater blood loss and greater amount of blood transfused were risk factors in cases of graft replacement. The risk factors associated with preoperative death were advanced age and acidosis due to severe shock. The correct initial diagnoses were made in prior hospital in 28 cases. Incorrect diagnoses, which were made more often in non-shock patients than in patients in shock, were abdominal pain of unknown origin in 6, ureterolithiasis in 4, lumbago, appendicitis and gastritis in 2 cases each. The delayed diagnosis might have resulted in more severe shock or cardiac arrest. In conclusion, to reduce the mortality of ruptured AAA, correct initial diagnosis and expeditious preoperative management are most important.
7.Outcome of Ruptured Abdominal Aortic Aneurysms in Patients over 80 Years Old.
Masayoshi Nishimoto ; Hitoshi Fukumoto ; Yasuhisa Nishimoto ; Hironaga Okawa ; Akira Fujiwara
Japanese Journal of Cardiovascular Surgery 1998;27(2):81-86
The hospital records of 59 patients treated for ruptured abdominal aortic aneurysms during the past eleven years were reviewed. The patients were classified into two groups: an elderly group aged 80 years old or wore (18 cases) and a control group aged under 80 years old (41 cases). Previous diagnoses of abdominal aortic aneurysm had been made more frequently in the aged group (44.4%) than in the control group (22%). Of the patients who fell into shock preoperatively, only 6 patients (60%) received graft replacements in the aged group, but all patients received graft replacements in the control group. Graft replacements were performed as safely in non-shock patients in the elderly group as in cases of non-ruptured abdominal aortic aneurysm. The overall survival rate including non-operative cases in the elderly group (38.9%) was lower than that in the control group (61%). The survival rates in patients receiving graft replacemes showed no significant difference between the elderly group (63.3%) and the control group (67.6%). Many of the aged patients who fell into shock due to aortic rupture died without receiving surgery. Hypovolemic shock which results in ischemia in vital organs is the most likely major cause of death in patients of advanced age. In conclusion, graft replacements should be performed electively and safely before aneurysmal rupture, particularly in elderly patients.
8.A Successful Case of Open Stent-Grafting for an Impending Ruptured Acute Type B Aortic Dissection
Kan Hamori ; Masayoshi Nishimoto ; Keiichi Furubayashi ; Hitoshi Fukumoto
Japanese Journal of Cardiovascular Surgery 2005;34(4):272-275
A 70-year-old man was admitted suffering from chest and back pain. He was assessed by enhanced computed tomography (eCT) and a thrombosed acute DeBakey type IIIb aortic dissection with an ulcer like projection (ULP) was diagnosed and treated medically. Five days later, he complained suddenly of dyspnea and was diagnosed by eCT as having a pulmonary thromboembolism. Anticoagulant therapy was started reluctantly. The patient's symptoms improved, however, 16 days later he complained of severe chest and back pain. Enhanced CT showed enlargement of the ULP, which was diagnosed as an impending aortic rupture. Open stent-grafting was selected as a less-invasive treatment method. A stent-graft was introduced into the descending aorta via the transected aortic arch and the entry of the ULP was closed. Postoperative course was smooth and uneventful. We consider that open stent-grafting via the aortic arch is an alternative method for repair of acute type B aortic dissection with an ULP in the descending aorta, in cases where direct closure of the intimal tear is difficult.
9.A Case of Early Progressive Aortic Valve Regurgitation after Coronary Artery Bypass Grafting in Aortitis Patient with Negative Findings for C-Reactive Protein and the Erythrocyte Sedimentation Rate
Kosuke Mukaihara ; Goichi Yotsumoto ; Tomoyuki Matsuba ; Kazuhisa Matsumoto ; Takayuki Ueno ; Yoshihiro Fukumoto ; Hitoshi Toyohira ; Masafumi Yamashita
Japanese Journal of Cardiovascular Surgery 2012;41(5):238-242
We report the case of a 55-year-old woman with aortitis syndrome. She was admitted to our hospital because of repeated chest pain and syncope. An electrocardiogram and the laboratory data suggested acute myocardial infarction, and coronary angiography showed severe bilateral coronary ostial stenosis. No valvular disease was observed. Aortitis syndrome was suspected because of the stenosis of the brachiocephalic artery in addition to the bilateral coronary ostial stenosis, while the patient did not have elevated C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Coronary artery bypass grafting was performed, and the patient's postoperative course was uneventful. However, she again experienced chest pain 9 months after surgery due to aortic regurgitation (AR) and diffuse narrowing change of the left internal thoracic artery graft. Aortic valve replacement and Re-CABG was performed, and the patient was treated with steroid therapy postoperatively. The postoperative course was uneventful, but the patient thereafter died due to bleeding of a malignant adrenal tumor at 21 months after the second surgery.
10.Type A Aortic Dissection during the Treatment of Tuberculous Pericarditis
Tomoyuki Matsuba ; Goichi Yotsumoto ; Kousuke Mukaihara ; Takayuki Ueno ; Kazuhisa Matsumoto ; Yoshihiro Fukumoto ; Hitoshi Toyohira ; Masafumi Yamashita
Japanese Journal of Cardiovascular Surgery 2012;41(1):16-20
A 69-year-old woman, who had undergone a right nephrectomy for renal tuberculosis in her teens, was admitted with a low grade fever, anorexia and progressive dyspnea. Transthoracic echocardiography showed cardiac tamponade and chest CT revealed an enlarged ascending aorta. She was treated with pericardiocentesis. Specimens of pericardial effusion failed to demonstrate any acid-fast bacilli, but they did reveal a high level of adnosine deaminase (72 IU/l). A diagnosis of tuberculous pericarditis was considered, and antituberculous chemotherapy was started. However, he presented with severe back pain 32 days later and CT revealed type A acute aortic dissection. We therefore replaced the ascending aorta and aortic root. A histopathological examination of the ascending aorta revealed evidence of a granulomatous inflammatory reaction with Langhans giant cells. She thereafter received antituberculous chemotherapy with 4 drugs for 2 months, with continued rifampicin and isoniazid treatment. There was no evidence of any graft infection after 70 days.