1.Standardization of Prophylactic Measures Against Catheter-related Urinary Tract Infections
Yuka NAGAI ; Hitomi MAENO ; Yoko HOSHI ; Mayumi SATO ; Satomi YUHARA
Journal of the Japanese Association of Rural Medicine 2014;63(1):70-75
Urinary tract infections (UTIs) are among the most common entities in hospitals, accounting for about 40% of nosocomial infections. It is said that more than 80% of UTIs are associated with the use of catheters. The discharge opening of the Uro Bag, a type of urine storing bag, is alive with bacteria. The microorganisms can enter the bag and then bladder, causing UTIs. It can also be said that the longer the catheters are used, the greater the risk of catheter-related UTIs becomes. Furthermore, Pseudomonas aeruginosa, Staphylococcus aureas, Serratia mareescensand other kinds of bacteria that have acquired the resistance to drugs are increasing. The incidence of mixed infections with different organisms are on the rise. Such being the present situation, to prevent UTIS we think that the proper management of urinary catheterization and right use of urethral catheters are of the primary importance. Those health providers who handle catheters frequently need to take every precaution against inadvertently acting as intermediaries in the incidence of nosocomial infectious diseases including catheter-related UTIs. Recently, we reviewed the prophylactic measures which had been taken by our hospital, assessed the findings using the checklist made by the Nosocomial Infection Prevention Committee. Later, we held a seminar and discussed the standardization of prophylactic measures. As a result, the assessment items which were rated low in June marked 100% in September and March. Thus, our efforts have led the hospital employees to deepen their knowledge and understanding of the need to watch out nosocomial infection constantly. For the guidance of employees, we included in the educational program on-the-job training, which proved to be helpful for the trainees to have imagery. To maintain the effect of infection prevention and to keep up the interest awakened in the hospital staff, the holding of seminars and meetings for reviewing on a regular basis are called for.
2.Enhanced case finding and self-isolation measures in the early phase of SARS-CoV-2 Omicron transmission, Osaka, Japan, December 2021–January 2022
Miho Kobayashi ; Kensaku Kakimoto ; Yuichiro Yahata ; Yusuke Kobayashi ; Hitomi Nagai ; Chisato Tanikake ; Kazumi Fukumura ; Keiko Date ; Hiromi Murata ; Sae Kitagawa ; Yuki Yoshida ; Yui Kamoda ; Miho Akazaki ; Masaaki Tanabe ; Chika Shirai ; Tomoe Shimada ; Taro Kamigaki ; Tsuyoshi Sekizuka ; Makoto Kuroda ; Tomimasa Sunagawa
Western Pacific Surveillance and Response 2025;16(2):29-38
Objective: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant B.1.1.529 (Omicron) was first detected in Japan in November 2021. In Osaka, public health centres subsequently increased active case finding and encouraged self-isolation. This study investigated the effectiveness of these countermeasures.
Methods: Cases targeted for analysis were persons who had neither recently travelled abroad nor had contact with foreign tourists but tested positive for SARS-CoV-2 between 24 November 2021 and 4 January 2022 and were suspected or confirmed to have the Omicron variant. We performed a descriptive analysis and calculated the reproduction number (R) for each generation using the branching process method. Genomic sequencing data were analysed to plot a haplotype network.
Results: A total of 251 cases were analysed. The median age was 30 years, and 46% (115/251) were in their 20s or younger. The first Omicron case in Osaka was detected on 21 December 2021. Local public health centres conducted health monitoring and contact tracing. We analysed R, using information from six clusters, including 42 pairs with a clear relationship between the case and the infected contact (infector–infectee pairs); the clusters had 19, 21 and 2 cases in each subsequent generation. The basic R (t = 0) was estimated to be 3.2, and subsequent generations (t = 1, 2) of R decreased to 1.1 and 0.1, respectively. The haplotype network showed that these cases constituted a monophyletic group with others detected around Osaka, indicating that these case-related clusters had been contained and were not involved in the nationwide Omicron waves.
Discussion: Active case finding and self-isolation were found to be effective in limiting the spread of an emerging novel variant.