The serum activity levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are important biochemical indicators of changes in the liver and coronary system function. The correct determination of changes in the activity levels of the transferases is essential for differential diagnosis and appropriate treatment of the diseases. Goal: The aim of this study was to determine the mean activity levels of ALT and AST of the Mongolian population. Materials and Methods: Serum was separated from morning blood samples collected from 1732 individuals 15-64 years of age (706 males, 1026 females) from 21 aimags and Ulaanbaatar city, and stored at -30°C until analysis. Activity levels of alanine aminotransferase and aspartate aminotransferase were determined using photometric system. Results: The overall mean serum activity level of AST was 25.52 U/L and of ALT was 22.60 U/L. No statistically significant differences were observed between the surveyed from Ulaanbaatar and from rural area as well as between sexes (p>0.05 for both ALT and AST). When the survey participants were divided into five age groups (15-24 years, 25-34 years, 35-44 years, 45-54 years and 55-64 years of age) and their mean activity levels of AST and ALT were compared, it was observed that the activity of both enzymes increased with age (p<0.05)

Background: Reference values are very important for the clinical decisions in laboratory diagnosis and clinical management of patients. Method: A total of 340 adults (apparently healthy individuals) between 18 to 70 years resident in the Ulaanbaatar city were randomly selected and enrolled in this survey. 340 adults made up of 170 males, 170 females were assessed by a clinician to be healthy. About 5 ml of blood was collected with EDTA test tube and analyzed using automated analyser to enumerate the hematological parameters (red blood cell, white blood cell, hemoglobin and haematocrit). Reference values were determined at 2.5^th and 97.5^th percentiles. Results: Reference values estabilished include: red blood cell 4.69-6.04×1012/L, white blood cell 3.98-9.11×109/L, haemoglobin 145-176 g/L, haematocrit 42.6-52.9% for males and red blood cell 4.10-5.20×1012/L, white blood cell 3.50-9.08×109/L, haemoglobin 121.8-148.2 g/L, haematocrit 36-44.7% for females. Conclusion We were determined mean and reference range of haematological parameters (red blood cell, white blood cell, haemoglobin, haemotocrit) which are important for assessing the nutritional status of adults according to the international standard methodology. The international reference range shows that white blood cells counts do not indicate gender and our data (р=0.0964 are statistically insignificant) also offers no significant difference was found between samples for male and female subjects.