1.Construction of Anti-Doping Database for Pharmacist
Kensuke Usui ; Harutaka Komuro ; Chihiro Ito ; Michiyo Ito ; Koji Masubuchi ; Soichi Shibata ; Jun Kainuma ; Gaku Inoue ; Hiroyuki Nojima ; Koichiro Atsuda
Japanese Journal of Drug Informatics 2012;13(4):189-193
Objective: The sports community has placed its great hope on pharmacist since the establishment of the Accredited Sports Pharmacist System. Thus, we constructed an anti-doping database for pharmacist so that pharmacist can support appropriate drug use and contribute to the sports community.
Methods: The database was constructed by using Microsoft®Access 2007, based on our previously prepared anti-doping list.
Results: 686 prescription drugs and 268 ingredients for non-prescription drug were registered in the data base. It was able to retrieve the advisability of use for athlete, blood half-life and the other notes of the drugs easily and promptly.
Conclusion: We confirm that pharmacist can provide drug information easily, promptly and from the viewpoint of pharmaceutics by utilizing the database including necessary information for anti-doping.
2.Feasibility, Efficacy, and Predictive Factors for the Technical Success of Endoscopic Nasogallbladder Drainage: A Prospective Study.
Kei YANE ; Hiroyuki MAGUCHI ; Akio KATANUMA ; Kuniyuki TAKAHASHI ; Manabu OSANAI ; Toshifumi KIN ; Ryo TAKAKI ; Kazuyuki MATSUMOTO ; Katsushige GON ; Tomoaki MATSUMORI ; Akiko TOMONARI ; Masanori NOJIMA
Gut and Liver 2015;9(2):239-246
BACKGROUND/AIMS: Several studies have shown the usefulness of endoscopic nasogallbladder drainage (ENGBD) in patients with acute cholecystitis. However, the procedure is difficult, and factors that affect technical success have not yet been clarified. We conducted a prospective study to evaluate the technical feasibility, efficacy, and predictive factors for the technical success of ENGBD in patients with acute cholecystitis. METHODS: All patients with moderate or severe acute cholecystitis who were enrolled underwent ENGBD between April 2009 and April 2011. Patients with surgically altered anatomy or pancreatobiliary malignancies were excluded. The primary outcomes included technical success, clinical success, and complications. Factors that could affect the technical success were also examined. RESULTS: Of the 27 patients who underwent ENGBD during the study period, technical success was achieved in 21 (78%) and clinical improvement was achieved in 20 (95%). Early complications were encountered in four patients (15%). Gallbladder wall thickness (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.08 to 2.47) and age (OR, 1.16; 95% CI, 1.00 to 1.35) were effective predictors of technical failure. CONCLUSIONS: ENGBD was effective in resolving acute cholecystitis; however, this modality was technically challenging and had a limited success rate. Because of technical difficulties, ENGBD should be reserved for limited indications.
Age Factors
;
Aged
;
Aged, 80 and over
;
Cholecystitis, Acute/*surgery
;
Drainage/*methods
;
Endoscopy, Gastrointestinal/*methods
;
Feasibility Studies
;
Female
;
Gallbladder/pathology/*surgery
;
Humans
;
Male
;
Middle Aged
;
Odds Ratio
;
Postoperative Complications/epidemiology
;
Prospective Studies
;
Sphincterotomy, Endoscopic
;
Treatment Outcome
3.Feasibility, Efficacy, and Predictive Factors for the Technical Success of Endoscopic Nasogallbladder Drainage: A Prospective Study.
Kei YANE ; Hiroyuki MAGUCHI ; Akio KATANUMA ; Kuniyuki TAKAHASHI ; Manabu OSANAI ; Toshifumi KIN ; Ryo TAKAKI ; Kazuyuki MATSUMOTO ; Katsushige GON ; Tomoaki MATSUMORI ; Akiko TOMONARI ; Masanori NOJIMA
Gut and Liver 2015;9(2):239-246
BACKGROUND/AIMS: Several studies have shown the usefulness of endoscopic nasogallbladder drainage (ENGBD) in patients with acute cholecystitis. However, the procedure is difficult, and factors that affect technical success have not yet been clarified. We conducted a prospective study to evaluate the technical feasibility, efficacy, and predictive factors for the technical success of ENGBD in patients with acute cholecystitis. METHODS: All patients with moderate or severe acute cholecystitis who were enrolled underwent ENGBD between April 2009 and April 2011. Patients with surgically altered anatomy or pancreatobiliary malignancies were excluded. The primary outcomes included technical success, clinical success, and complications. Factors that could affect the technical success were also examined. RESULTS: Of the 27 patients who underwent ENGBD during the study period, technical success was achieved in 21 (78%) and clinical improvement was achieved in 20 (95%). Early complications were encountered in four patients (15%). Gallbladder wall thickness (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.08 to 2.47) and age (OR, 1.16; 95% CI, 1.00 to 1.35) were effective predictors of technical failure. CONCLUSIONS: ENGBD was effective in resolving acute cholecystitis; however, this modality was technically challenging and had a limited success rate. Because of technical difficulties, ENGBD should be reserved for limited indications.
Age Factors
;
Aged
;
Aged, 80 and over
;
Cholecystitis, Acute/*surgery
;
Drainage/*methods
;
Endoscopy, Gastrointestinal/*methods
;
Feasibility Studies
;
Female
;
Gallbladder/pathology/*surgery
;
Humans
;
Male
;
Middle Aged
;
Odds Ratio
;
Postoperative Complications/epidemiology
;
Prospective Studies
;
Sphincterotomy, Endoscopic
;
Treatment Outcome