We should decide the dose in renal insufficiency according to an attachment document, estimated by Cockroft-Gault's formula. It is better not to decide the dose only byexcretion route. In addition, we should not administer the nephrotoxic drugs, especially NSAIDs, to renal insufficiency.
Also, it is necessary to pay enough attention to the overdose of drugs, which do not cause renal toxicity but cause dangerous side effects to the central nervous system.
Many attachment documents have a lot of lacks in the mention for renal insufficiency and need to be improved.